Enhancing NMDA Receptor Function: Recent Progress on Allosteric Modulators
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Title
Enhancing NMDA Receptor Function: Recent Progress on Allosteric Modulators
Authors
Keywords
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Journal
NEURAL PLASTICITY
Volume 2017, Issue -, Pages 1-11
Publisher
Hindawi Limited
Online
2017-01-10
DOI
10.1155/2017/2875904
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Note: Only part of the references are listed.- A double-blind randomized study assessing safety and efficacy following one-year adjunctive treatment with bitopertin, a glycine reuptake inhibitor, in Japanese patients with schizophrenia
- (2016) Yoshio Hirayasu et al. BMC Psychiatry
- D-cycloserine in Schizophrenia: New Strategies for Improving Clinical Outcomes by Enhancing Plasticity
- (2016) Donald Goff Current Neuropharmacology
- The Development of Rapastinel (Formerly GLYX-13); A Rapid Acting and Long Lasting Antidepressant
- (2016) Joseph Moskal et al. Current Neuropharmacology
- Cost-effectiveness of donepezil and memantine in moderate to severe Alzheimer's disease (the DOMINO-AD trial)
- (2016) Martin Knapp et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design
- (2016) Matthew Volgraf et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Functional and Molecular Properties, Physiological Functions, and Pathophysiological Roles of GluN2A in the Central Nervous System
- (2016) Yongjun Sun et al. MOLECULAR NEUROBIOLOGY
- NMDAR inhibition-independent antidepressant actions of ketamine metabolites
- (2016) Panos Zanos et al. NATURE
- Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants
- (2016) Ronald S Duman et al. NATURE MEDICINE
- Modulating NMDA Receptor Function with d-Amino Acid Oxidase Inhibitors: Understanding Functional Activity in PCP-Treated Mouse Model
- (2016) Henry Sershen et al. NEUROCHEMICAL RESEARCH
- Advances in understanding the functions of native GlyT1 and GlyT2 neuronal glycine transporters
- (2016) Cristina Romei et al. NEUROCHEMISTRY INTERNATIONAL
- Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function
- (2016) David H. Hackos et al. NEURON
- An NMDA Receptor-Dependent Mechanism Underlies Inhibitory Synapse Development
- (2016) Xinglong Gu et al. Cell Reports
- Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics
- (2015) Chadi G. Abdallah et al. Annual Review of Medicine
- Rapastinel (GLYX-13) has therapeutic potential for the treatment of post-traumatic stress disorder: Characterization of a NMDA receptor-mediated metaplasticity process in the medial prefrontal cortex of rats
- (2015) Jeffrey Burgdorf et al. BEHAVIOURAL BRAIN RESEARCH
- Allosteric modulators of NMDA receptors: multiple sites and mechanisms
- (2015) Shujia Zhu et al. CURRENT OPINION IN PHARMACOLOGY
- The NMDA receptor ‘glycine modulatory site’ in schizophrenia: d-serine, glycine, and beyond
- (2015) Darrick T Balu et al. CURRENT OPINION IN PHARMACOLOGY
- Tonically active NMDA receptors - a signalling mechanism critical for interneuronal excitability in the CA1 stratum radiatum
- (2015) Ilse Riebe et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Impaired Attention and Synaptic Senescence of the Prefrontal Cortex Involves Redox Regulation of NMDA Receptors
- (2015) M. Guidi et al. JOURNAL OF NEUROSCIENCE
- Randomized Proof of Concept Trial of GLYX-13, an N-Methyl-D-Aspartate Receptor Glycine Site Partial Agonist, in Major Depressive Disorder Nonresponsive to a Previous Antidepressant Agent
- (2015) SHELDON PRESKORN et al. Journal of Psychiatric Practice
- Efficacy and adverse effects of memantine treatment for Alzheimer’s disease from randomized controlled trials
- (2015) Jue Jiang et al. NEUROLOGICAL SCIENCES
- The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus
- (2015) J. Burgdorf et al. NEUROSCIENCE
- Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain
- (2015) Jennifer K. Forsyth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The impact of NMDA receptor hypofunction on GABAergic neurons in the pathophysiology of schizophrenia
- (2015) Samuel M. Cohen et al. SCHIZOPHRENIA RESEARCH
- GluN2D-containing NMDA receptors-mediate synaptic currents in hippocampal interneurons and pyramidal cells in juvenile mice
- (2015) Jakob von Engelhardt et al. Frontiers in Cellular Neuroscience
- Allosteric modulation of GluN2C/GluN2D-containing NMDA receptors bidirectionally modulates dopamine release: implication for Parkinson's disease
- (2014) X Zhang et al. BRITISH JOURNAL OF PHARMACOLOGY
- NMDA receptor structures reveal subunit arrangement and pore architecture
- (2014) Chia-Hsueh Lee et al. NATURE
- Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA Receptors
- (2014) Kasper B. Hansen et al. NEURON
- Crystal structure of a heterotetrameric NMDA receptor ion channel
- (2014) E. Karakas et al. SCIENCE
- Inhibition of Glycine Transporter-I as a Novel Mechanism for the Treatment of Depression
- (2013) Chih-Chia Huang et al. BIOLOGICAL PSYCHIATRY
- Enhanced hippocampal neuronal excitability and LTP persistence associated with reduced behavioral flexibility in the maternal immune activation model of schizophrenia
- (2013) Shakuntala Savanthrapadian et al. HIPPOCAMPUS
- Triheteromeric NMDA Receptors at Hippocampal Synapses
- (2013) K. R. Tovar et al. JOURNAL OF NEUROSCIENCE
- Glycine transporters as novel therapeutic targets in schizophrenia, alcohol dependence and pain
- (2013) Robert J. Harvey et al. NATURE REVIEWS DRUG DISCOVERY
- NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
- (2013) Pierre Paoletti et al. NATURE REVIEWS NEUROSCIENCE
- NMDA receptors in nervous system diseases
- (2013) Qiang Zhou et al. NEUROPHARMACOLOGY
- Add-on Treatment of Benzoate for Schizophrenia
- (2013) Hsien-Yuan Lane et al. JAMA Psychiatry
- Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression
- (2012) James W. Murrough et al. BIOLOGICAL PSYCHIATRY
- Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists
- (2012) Thomas Papouin et al. CELL
- Opposing Roles of Synaptic and Extrasynaptic NMDA Receptor Signaling in Cocultured Striatal and Cortical Neurons
- (2012) A. M. Kaufman et al. JOURNAL OF NEUROSCIENCE
- Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-d-aspartate receptors
- (2012) Mark W. Irvine et al. NEUROCHEMISTRY INTERNATIONAL
- Pharmacological modulation of NMDA receptor activity and the advent of negative and positive allosteric modulators
- (2012) Daniel T. Monaghan et al. NEUROCHEMISTRY INTERNATIONAL
- The NMDA receptor as a target for cognitive enhancement
- (2012) Graham L. Collingridge et al. NEUROPHARMACOLOGY
- A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior
- (2011) M Carlén et al. MOLECULAR PSYCHIATRY
- GABAergic interneuron origin of schizophrenia pathophysiology
- (2011) Kazu Nakazawa et al. NEUROPHARMACOLOGY
- NMDA receptors, cognition and schizophrenia – Testing the validity of the NMDA receptor hypofunction hypothesis
- (2011) Gary Gilmour et al. NEUROPHARMACOLOGY
- Stroke intervention pathways: NMDA receptors and beyond
- (2011) Ted Weita Lai et al. TRENDS IN MOLECULAR MEDICINE
- Strategies to Enhance N-Methyl-D-Aspartate Receptor-Mediated Neurotransmission in Schizophrenia, a Critical Review and Meta-Analysis
- (2010) Guochuan Tsai et al. CURRENT PHARMACEUTICAL DESIGN
- Triheteromeric NR1/NR2A/NR2B Receptors Constitute the MajorN-Methyl-d-aspartate Receptor Population in Adult Hippocampal Synapses
- (2010) Claudia Rauner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Family of Negative and Positive Allosteric Modulators of NMDA Receptors
- (2010) B. M. Costa et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
- (2010) Giles E. Hardingham et al. NATURE REVIEWS NEUROSCIENCE
- Long-term depression in the CNS
- (2010) Graham L. Collingridge et al. NATURE REVIEWS NEUROSCIENCE
- Glutamate Receptor Ion Channels: Structure, Regulation, and Function
- (2010) S. F. Traynelis et al. PHARMACOLOGICAL REVIEWS
- A randomized, double-blind, placebo-controlled comparison study of sarcosine ( N-methylglycine) and d-serine add-on treatment for schizophrenia
- (2009) Hsien-Yuan Lane et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain
- (2009) H. Yuan et al. JOURNAL OF NEUROSCIENCE
- Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes
- (2009) Juan E Belforte et al. NATURE NEUROSCIENCE
- Cell Type-Specific Development of NMDA Receptors in the Interneurons of Rat Prefrontal Cortex
- (2009) Huai-Xing Wang et al. NEUROPSYCHOPHARMACOLOGY
- The involvement of the NMDA receptor d-serine/glycine site in the pathophysiology and treatment of schizophrenia
- (2009) Viviane Labrie et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- d-Amino acids in the brain: d-serine in neurotransmission and neurodegeneration
- (2008) Herman Wolosker et al. FEBS Journal
- NMDA receptors in clinical neurology: excitatory times ahead
- (2008) Lorraine V Kalia et al. LANCET NEUROLOGY
- Allosteric modulation of NMDA receptor via elevation of brain glycine and d-serine: The therapeutic potentials for schizophrenia
- (2008) Charles R. Yang et al. PHARMACOLOGY & THERAPEUTICS
- Glycine and d-serine, but not d-cycloserine, attenuate prepulse inhibition deficits induced by NMDA receptor antagonist MK-801
- (2008) Nobuhisa Kanahara et al. PSYCHOPHARMACOLOGY
- Differential Roles of NMDA Receptor Subtypes in Ischemic Neuronal Cell Death and Ischemic Tolerance
- (2008) Min Chen et al. STROKE
- Sarcosine (N-Methylglycine) Treatment for Acute Schizophrenia: A Randomized, Double-Blind Study
- (2007) Hsien-Yuan Lane et al. BIOLOGICAL PSYCHIATRY
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