Discovery of T-cell Driven Subunit Vaccines from Zika Virus Genome: An Immunoinformatics Approach

Zika Virus on the Move

(2016)   CELL

Zika virus: a new global threat for 2016

(2016) The Lancet   LANCET

Zika virus genome from the Americas

(2016) Antoine Enfissi et al.   LANCET

Zika virus: time to move from case reports to case control

(2016) Didier Musso et al.   LANCET INFECTIOUS DISEASES

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

(2016) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Zika Virus in the Americas — Yet Another Arbovirus Threat

(2016) Anthony S. Fauci et al.   NEW ENGLAND JOURNAL OF MEDICINE

A race to explain Brazil's spike in birth defects

(2016) G. Vogel   SCIENCE

Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic

(2016) Zheng Zhu et al.   Emerging Microbes & Infections

Gapped sequence alignment using artificial neural networks: application to the MHC class I system

(2015) Massimo Andreatta et al.   BIOINFORMATICS

Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification

(2015) Massimo Andreatta et al.   IMMUNOGENETICS

Identification of cytotoxic T lymphocyte epitopes in dengue virus serotype 1

(2015) Zhiliang Duan et al.   JOURNAL OF MEDICAL VIROLOGY

Biology of Zika Virus Infection in Human Skin Cells

(2015) Rodolphe Hamel et al.   JOURNAL OF VIROLOGY

First report of autochthonous transmission of Zika virus in Brazil

(2015) Camila Zanluca et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Epitope-based peptide vaccine design and target site depiction against Ebola viruses: an immunoinformatics study

(2015) M. A. Khan et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Identification of conserved and HLA-A*2402-restricted epitopes in Dengue virus serotype 2

(2015) Zhi-Liang Duan et al.   VIRUS RESEARCH

Inferring Protective CD8+ T-Cell Epitopes for NS5 Protein of Four Serotypes of Dengue Virus Chinese Isolates Based on HLA-A, -B and -C Allelic Distribution: Implications for Epitope-Based Universal Vaccine Design

(2015) Jiandong Shi et al.   PLoS One

The Immunodominance Change and Protection of CD4+ T-Cell Responses Elicited by an Envelope Protein Domain III-Based Tetravalent Dengue Vaccine in Mice

(2015) Hsin-Wei Chen et al.   PLoS One

Dengue virus specific dual HLA binding T cell epitopes induce CD8+ T cell responses in seropositive individuals

(2015) Joseph D Comber et al.   Human Vaccines & Immunotherapeutics

Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases

(2014) Frances E Terry et al.   Expert Review of Vaccines

Elucidating the role of T cells in protection against and pathogenesis of dengue virus infections

(2014) Anuja Mathew et al.   Future Microbiology

The immune epitope database (IEDB) 3.0

(2014) Randi Vita et al.   NUCLEIC ACIDS RESEARCH

Peptide-pulsed dendritic cells induce the hepatitis C viral epitope-specific responses of naïve human T cells

(2014) Sasmita Mishra et al.   VACCINE

Cross-conservation of T-cell epitopes

(2014) Anne S De Groot et al.   Human Vaccines & Immunotherapeutics

PREDIVAC: CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity

(2013) Patricio Oyarzún et al.   BMC BIOINFORMATICS

Genome-based approaches to develop epitope-driven subunit vaccines against pathogens of infective endocarditis

(2013) Vani Priyadarshini et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Yellow Fever Vaccination Elicits Broad Functional CD4+T Cell Responses That Recognize Structural and Nonstructural Proteins

(2013) Eddie A. James et al.   JOURNAL OF VIROLOGY

Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

(2013) D. Weiskopf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T-Cell Memory Responses Elicited by Yellow Fever Vaccine are Targeted to Overlapping Epitopes Containing Multiple HLA-I and -II Binding Motifs

(2013) Andréa Barbosa de Melo et al.   PLoS Neglected Tropical Diseases

Computational approaches to identify common subunit vaccine candidates against bacterial meningitis

(2013) Manne Munikumar et al.   Interdisciplinary Sciences-Computational Life Sciences

Computer aided subunit vaccine design against pathogenic Leptospira serovars

(2012) Amineni Umamaheswari et al.   Interdisciplinary Sciences-Computational Life Sciences

Human Leukocyte Antigen (HLA) Class I Restricted Epitope Discovery in Yellow Fewer and Dengue Viruses: Importance of HLA Binding Strength

(2011) Ole Lund et al.   PLoS One

Peptide binding predictions for HLA DR, DP and DQ molecules

(2010) Peng Wang et al.   BMC BIOINFORMATICS

Selection and identification of B-cell epitope on NS1 protein of dengue virus type 2

(2010) Lan Jiang et al.   VIRUS RESEARCH

Identification of Continuous Human B-Cell Epitopes in the Envelope Glycoprotein of Dengue Virus Type 3 (DENV-3)

(2009) Andréa N. M. Rangel da Silva et al.   PLoS One

A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach

(2008) Peng Wang et al.   PLoS Computational Biology

Conservation and Variability of Dengue Virus Proteins: Implications for Vaccine Design

(2008) Asif M. Khan et al.   PLoS Neglected Tropical Diseases