Elucidating the role of T cells in protection against and pathogenesis of dengue virus infections

Dengue vaccines: recent developments, ongoing challenges and current candidates

(2013) Monica A McArthur et al.   Expert Review of Vaccines

Distinct activation phenotype of a highly conserved novel HLA-B57-restricted epitope during dengue virus infection

(2013) Elizabeth Townsley et al.   IMMUNOLOGY

Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

(2013) D. Weiskopf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of serotype-specific T cell responses to highly conserved regions of the dengue viruses

(2012) G. N. Malavige et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice

(2012) Smita Jaiswal et al.   IMMUNOLOGY

Conserved MHC Class I–Presented Dengue Virus Epitopes Identified by Immunoproteomics Analysis Are Targets for Cross-Serotype Reactive T-Cell Response

(2012) James S. Testa et al.   JOURNAL OF INFECTIOUS DISEASES

Differential Targeting of Viral Components by CD4+ versus CD8+ T Lymphocytes in Dengue Virus Infection

(2012) L. Rivino et al.   JOURNAL OF VIROLOGY

Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

(2012) Arunee Sabchareon et al.   LANCET

Broadly Neutralizing Antibodies Present New Prospects to Counter Highly Antigenically Diverse Viruses

(2012) D. R. Burton et al.   SCIENCE

Molecular Mechanisms Involved in Antibody-Dependent Enhancement of Dengue Virus Infection in Humans

(2012) Jacky Flipse et al.   TRAFFIC

Animal Models of Dengue Virus Infection

(2012) Simona Zompi et al.   Viruses-Basel

Primary Vaccination with Low Dose Live Dengue 1 Virus Generates a Proinflammatory, Multifunctional T Cell Response in Humans

(2012) Janet C. Lindow et al.   PLoS Neglected Tropical Diseases

Immune Response to Dengue Virus and Prospects for a Vaccine

(2011) Brian R. Murphy et al.   Annual Review of Immunology

Critical issues in dengue vaccine development

(2011) Stephen J. Thomas et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Dengue virus-specific CD4+ and CD8+ T lymphocytes target NS1, NS3 and NS5 in infected Indian rhesus macaques

(2011) Katherine M. Mladinich et al.   IMMUNOGENETICS

Insights into HLA-Restricted T Cell Responses in a Novel Mouse Model of Dengue Virus Infection Point toward New Implications for Vaccine Design

(2011) Daniela Weiskopf et al.   JOURNAL OF IMMUNOLOGY

Intracellular Cytokine Production by Dengue Virus–specific T cells Correlates with Subclinical Secondary Infection

(2011) Steven Hatch et al.   JOURNAL OF INFECTIOUS DISEASES

HLA Class I and Class II Associations in Dengue Viral Infections in a Sri Lankan Population

(2011) Gathsaurie Neelika Malavige et al.   PLoS One

A human challenge model for dengue infection reveals a possible protective role for sustained interferon gamma levels during the acute phase of illness

(2011) V.J. Gunther et al.   VACCINE

Antibody-mediated neutralization of flaviviruses: A reductionist view

(2011) Kimberly A. Dowd et al.   VIROLOGY

Cross-Reactivity and Expansion of Dengue-Specific T cells During Acute Primary and Secondary Infections in Humans

(2011) Heather Friberg et al.   Scientific Reports

Tumor necrosis factor–alpha, transforming growth factor–β1, and interleukin-10 gene polymorphisms: implication in protection or susceptibility to dengue hemorrhagic fever

(2010) Ana B. Perez et al.   HUMAN IMMUNOLOGY

Memory CD8+ T cells from naturally acquired primary dengue virus infection are highly cross-reactive

(2010) Heather Friberg et al.   IMMUNOLOGY AND CELL BIOLOGY

Timing of CD8+ T Cell Responses in Relation to Commencement of Capillary Leakage in Children with Dengue

(2010) N. T. P. Dung et al.   JOURNAL OF IMMUNOLOGY

CD4+ T Cells Are Not Required for the Induction of Dengue Virus-Specific CD8+ T Cell or Antibody Responses but Contribute to Protection after Vaccination

(2010) L. E. Yauch et al.   JOURNAL OF IMMUNOLOGY

Identification of a dengue virus-specific HLA-A*0201-restricted CD8+T cell epitope

(2010) Jinsheng Wen et al.   JOURNAL OF MEDICAL VIROLOGY

Immunodominant T-cell responses to dengue virus NS3 are associated with DHF

(2010) T. Duangchinda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant nucleocapsid-like particles from dengue-2 virus induce protective CD4+ and CD8+ cells against viral encephalitis in mice

(2009) L. Gil et al.   INTERNATIONAL IMMUNOLOGY

The Yellow Fever Virus Vaccine Induces a Broad and Polyfunctional Human Memory CD8+ T Cell Response

(2009) R. S. Akondy et al.   JOURNAL OF IMMUNOLOGY

A Protective Role for Dengue Virus-Specific CD8+ T Cells

(2009) L. E. Yauch et al.   JOURNAL OF IMMUNOLOGY

TNFandLTAGene, Allele, and Extended HLA Haplotype Associations with Severe Dengue Virus Infection in Ethnic Thais

(2009) Sasijit Vejbaesya et al.   JOURNAL OF INFECTIOUS DISEASES

Dengue Virus Infection and Virus-Specific HLA-A2 Restricted Immune Responses in Humanized NOD-scid IL2rγnull Mice

(2009) Smita Jaiswal et al.   PLoS One

The Cellular Immune Response Plays an Important Role in Protecting Against Dengue Virus in the Mouse Encephalitis Model

(2009) Lázaro Gil et al.   VIRAL IMMUNOLOGY

Mouse models of dengue virus infection and disease

(2008) L YAUCH et al.   ANTIVIRAL RESEARCH

Human Effector and Memory CD8+ T Cell Responses to Smallpox and Yellow Fever Vaccines

(2008) Joseph D. Miller et al.   IMMUNITY

Understanding the contribution of cellular immunity to dengue disease pathogenesis

(2008) Anuja Mathew et al.   IMMUNOLOGICAL REVIEWS

Dengue in Vietnamese Infants—Results of Infection‐Enhancement Assays Correlate with Age‐Related Disease Epidemiology, and Cellular Immune Responses Correlate with Disease Severity

(2008) Tran Nguyen Bich Chau et al.   JOURNAL OF INFECTIOUS DISEASES

Cell-mediated immunity induced by chimeric tetravalent dengue vaccine in naive or flavivirus-primed subjects

(2008) Bruno Guy et al.   VACCINE

Antibodies play a greater role than immune cells in heterologous protection against secondary dengue virus infection in a mouse model

(2008) Jennifer L. Kyle et al.   VIROLOGY

Conservation and Variability of Dengue Virus Proteins: Implications for Vaccine Design

(2008) Asif M. Khan et al.   PLoS Neglected Tropical Diseases