Dietary and Microbial Metabolites in the Regulation of Host Immunity

Treating inflammation and infection in the 21st century: new hints from decoding resolution mediators and mechanisms

(2017) Charles N. Serhan   FASEB JOURNAL

Transmission of the gut microbiota: spreading of health

(2017) Hilary P. Browne et al.   NATURE REVIEWS MICROBIOLOGY

Gut microbiome, metabolome, and allergic diseases

(2017) So-ichiro Hirata et al.   ALLERGOLOGY INTERNATIONAL

The Specific Roles of Vitamins in the Regulation of Immunosurveillance and Maintenance of Immunologic Homeostasis in the Gut

(2017) Koji Hosomi et al.   Immune Network

Metabolic changes during B cell differentiation for the production of intestinal IgA antibody

(2016) Jun Kunisawa   CELLULAR AND MOLECULAR LIFE SCIENCES

Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43

(2016) W Wu et al.   Mucosal Immunology

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways

(2016) Jian Tan et al.   Cell Reports

Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions

(2015) Ashish Gurav et al.   BIOCHEMICAL JOURNAL

Lactate and short chain fatty acids produced by microbial fermentation downregulate proinflammatory responses in intestinal epithelial cells and myeloid cells

(2015) Carolina Iraporda et al.   IMMUNOBIOLOGY

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome

(2015) Laurence Macia et al.   Nature Communications

Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut

(2015) Jun Kunisawa et al.   Scientific Reports

Mode of Bioenergetic Metabolism during B Cell Differentiation in the Intestine Determines the Distinct Requirement for Vitamin B 1

(2015) Jun Kunisawa et al.   Cell Reports

Vitamin-mediated immune regulation in the development of inflammatory diseases

(2015) Hidehiko Suzuki et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Vitamins Mediate Immunological Homeostasis and Diseases at the Surface of the Body

(2015) Jun Kunisawa et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Redirection of Epithelial Immune Responses by Short-Chain Fatty Acids through Inhibition of Histone Deacetylases

(2015) May Young Lin et al.   Frontiers in Immunology

Systematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes

(2015) Stefanía Magnúsdóttir et al.   Frontiers in Genetics

TLR5-Mediated Sensing of Gut Microbiota Is Necessary for Antibody Responses to Seasonal Influenza Vaccination

(2014) Jason Z. Oh et al.   IMMUNITY

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy-cis-12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway

(2014) Junki Miyamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells

(2014) Sidonia B.G. Eckle et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Histone Deacetylase Inhibitors Upregulate B Cell microRNAs That Silence AID and Blimp-1 Expression for Epigenetic Modulation of Antibody and Autoantibody Responses

(2014) Clayton A. White et al.   JOURNAL OF IMMUNOLOGY

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

(2014) Aurélien Trompette et al.   NATURE MEDICINE

Regulation of Intestinal Immune Responses through TLR Activation: Implications for Pro- and Prebiotics

(2014) Sander de Kivit et al.   Frontiers in Immunology

MAIT cells, surveyors of a new class of antigen: development and functions

(2013) Lionel Le Bourhis et al.   CURRENT OPINION IN IMMUNOLOGY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Polyunsaturated fatty acid saturation by gut lactic acid bacteria affecting host lipid composition

(2013) S. Kishino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Recognition of vitamin B metabolites by mucosal-associated invariant T cells

(2013) Onisha Patel et al.   Nature Communications

Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms

(2012) Janet E. Digby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mediator lipidomics in acute inflammation and resolution

(2012) M. Arita   JOURNAL OF BIOCHEMISTRY

Infection regulates pro-resolving mediators that lower antibiotic requirements

(2012) Nan Chiang et al.   NATURE

MR1 presents microbial vitamin B metabolites to MAIT cells

(2012) Lars Kjer-Nielsen et al.   NATURE

Probiotic Bacteria Produce Conjugated Linoleic Acid Locally in the Gut That Targets Macrophage PPAR γ to Suppress Colitis

(2012) Josep Bassaganya-Riera et al.   PLoS One

Short-Chain Fatty Acids Induce Pro-Inflammatory Cytokine Production Alone and in Combination with Toll-Like Receptor Ligands

(2011) Paria Mirmonsef et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Panorganismal Gut Microbiome−Host Metabolic Crosstalk

(2009) Francois-Pierre J. Martin et al.   JOURNAL OF PROTEOME RESEARCH

Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis

(2009) Matthew Spite et al.   NATURE

Peroxisome Proliferator-Activated Receptor γ Negatively Regulates Allergic Rhinitis in Mice

(2009) Naoko Fukui et al.   ALLERGOLOGY INTERNATIONAL

Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes

(2008) Sandrine P Claus et al.   Molecular Systems Biology

Enterococcus faecalis from newborn babies regulate endogenous PPAR  activity and IL-10 levels in colonic epithelial cells

(2008) A. Are et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA