Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases

Protein Interactions during the Flavivirus and Hepacivirus Life Cycle

(2017) Gisa Gerold et al.   MOLECULAR & CELLULAR PROTEOMICS

Tick-borne pathogens induce differential expression of genes promoting cell survival and host resistance in Ixodes ricinus cells

(2017) Karen L. Mansfield et al.   Parasites & Vectors

Pathogen-mediated manipulation of arthropod microbiota to promote infection

(2017) Nabil M. Abraham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infection-derived lipids elicit an immune deficiency circuit in arthropods

(2017) Dana K. Shaw et al.   Nature Communications

Tick-Pathogen Ensembles: Do Molecular Interactions Lead Ecological Innovation?

(2017) Alejandro Cabezas-Cruz et al.   Frontiers in Cellular and Infection Microbiology

Analysis of the entry mechanism of Crimean-Congo hemorrhagic fever virus, using a vesicular stomatitis virus pseudotyping system

(2016) Yuto Suda et al.   ARCHIVES OF VIROLOGY

Cross-Species Interferon Signaling Boosts Microbicidal Activity within the Tick Vector

(2016) Alexis A. Smith et al.   Cell Host & Microbe

Anaplasma phagocytophilumincreases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vectorIxodes scapularis

(2016) Alejandro Cabezas-Cruz et al.   Epigenetics

Apoptosis-related genes control autophagy and influence DENV-2 infection in the mosquito vector, Aedes aegypti

(2016) Matthew W. Eng et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Anti-complement activity of the Ixodes scapularis salivary protein Salp20

(2016) Dennis E. Hourcade et al.   MOLECULAR IMMUNOLOGY

AnIxodes ricinusTick Salivary Lectin Pathway Inhibitor ProtectsBorrelia burgdorferisensu lato from Human Complement

(2016) Alex Wagemakers et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Innate and adaptive immune responses to tick-borne flavivirus infection in sheep

(2016) Karen L. Mansfield et al.   VETERINARY MICROBIOLOGY

De novo assembly and annotation of the salivary gland transcriptome of Rhipicephalus appendiculatus male and female ticks during blood feeding

(2016) Minique H. de Castro et al.   Ticks and Tick-Borne Diseases

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

(2016) Monika Gulia-Nuss et al.   Nature Communications

Tissue-Specific Signatures in the Transcriptional Response to Anaplasma phagocytophilum Infection of Ixodes scapularis and Ixodes ricinus Tick Cell Lines

(2016) Pilar Alberdi et al.   Frontiers in Cellular and Infection Microbiology

Arsenophonus nasoniae and Rickettsiae Infection of Ixodes ricinus Due to Parasitic Wasp Ixodiphagus hookeri

(2016) Monika Bohacsova et al.   PLoS One

Integration of Ixodes ricinus genome sequencing with transcriptome and proteome annotation of the naïve midgut

(2015) Wibke J. Cramaro et al.   BMC GENOMICS

Chromatin-bound bacterial effector ankyrin A recruits histone deacetylase 1 and modifies host gene expression

(2015) Kristen E. Rennoll-Bankert et al.   CELLULAR MICROBIOLOGY

RNA interference and the vaccine effect of a subolesin homolog from the tick Rhipicephalus haemaphysaloides

(2015) Pengyun Lu et al.   EXPERIMENTAL AND APPLIED ACAROLOGY

Tick vaccines: current status and future directions

(2015) José de la Fuente et al.   Expert Review of Vaccines

Emerging horizons for tick-borne pathogens: from the ‘one pathogen–one disease’ vision to the pathobiome paradigm

(2015) Muriel Vayssier-Taussat et al.   Future Microbiology

Ixodes scapularis dystroglycan-like protein promotes Borrelia burgdorferi migration from the gut

(2015) Jeroen Coumou et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Integrated Metabolomics, Transcriptomics and Proteomics Identifies Metabolic Pathways Affected byAnaplasma phagocytophilumInfection in Tick Cells

(2015) Margarita Villar et al.   MOLECULAR & CELLULAR PROTEOMICS

Concordance of bacterial communities of two tick species and blood of their shared rodent host

(2015) Evelyn C. Rynkiewicz et al.   MOLECULAR ECOLOGY

Flying ticks: anciently evolved associations that constitute a risk of infectious disease spread

(2015) José de la Fuente et al.   Parasites & Vectors

Ixodes scapularis and Ixodes ricinus tick cell lines respond to infection with tick-borne encephalitis virus: transcriptomic and proteomic analysis

(2015) Sabine Weisheit et al.   Parasites & Vectors

Tissue- and time-dependent transcription in Ixodes ricinus salivary glands and midguts when blood feeding on the vertebrate host

(2015) Michalis Kotsyfakis et al.   Scientific Reports

Interactions between tick and transmitted pathogens evolved to minimise competition through nested and coherent networks

(2015) Agustín Estrada-Peña et al.   Scientific Reports

Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis

(2015) Nieves Ayllón et al.   PLoS Genetics

Infection and Co-infection Rates of Anaplasma phagocytophilum Variants, Babesia spp., Borrelia burgdorferi, and the Rickettsial Endosymbiont in Ixodes scapularis (Acari: Ixodidae) from Sites in Indiana, Maine, Pennsylvania, and Wisconsin

(2015) F. E. Steiner et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Identification and Characterization of Anaplasma phagocytophilum Proteins Involved in Infection of the Tick Vector, Ixodes scapularis

(2015) Margarita Villar et al.   PLoS One

Nuclease Tudor-SN Is Involved in Tick dsRNA-Mediated RNA Interference and Feeding but Not in Defense against Flaviviral or Anaplasma phagocytophilum Rickettsial Infection

(2015) Nieves Ayllón et al.   PLoS One

Plasmodium falciparumevades mosquito immunity by disrupting JNK-mediated apoptosis of invaded midgut cells

(2015) Urvashi N. Ramphul et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gut Microbiota of the Tick Vector Ixodes scapularis Modulate Colonization of the Lyme Disease Spirochete

(2014) Sukanya Narasimhan et al.   Cell Host & Microbe

Microbial Population Analysis of the Salivary Glands of Ticks; A Possible Strategy for the Surveillance of Bacterial Pathogens

(2014) Yongjin Qiu et al.   PLoS One

Crimean-Congo Hemorrhagic Fever Virus Entry into Host Cells Occurs through the Multivesicular Body and Requires ESCRT Regulators

(2014) Olena Shtanko et al.   PLoS Pathogens

Symbionts Commonly Provide Broad Spectrum Resistance to Viruses in Insects: A Comparative Analysis of Wolbachia Strains

(2014) Julien Martinez et al.   PLoS Pathogens

Blocking pathogen transmission at the source: reservoir targeted OspA-based vaccines against Borrelia burgdorferi

(2014) Maria Gomes-Solecki   Frontiers in Cellular and Infection Microbiology

“Candidatus Midichloriaceae” fam. nov. (Rickettsiales), an Ecologically Widespread Clade of Intracellular Alphaproteobacteria

(2013) Matteo Montagna et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Hard ticks and their bacterial endosymbionts (or would be pathogens)

(2013) Arunee Ahantarig et al.   FOLIA MICROBIOLOGICA

Anaplasma phagocytophilum Inhibits Apoptosis and Promotes Cytoskeleton Rearrangement for Infection of Tick Cells

(2013) Nieves Ayllón et al.   INFECTION AND IMMUNITY

The E3 Ubiquitin Ligase XIAP Restricts Anaplasma phagocytophilum Colonization of Ixodes scapularis Ticks

(2013) Maiara S. Severo et al.   JOURNAL OF INFECTIOUS DISEASES

Effects of Infection byArsenophonusandRickettsiaBacteria on the Locomotive Ability of the TicksAmblyomma americanum,Dermacentor variabilis, andIxodes scapularis

(2013) Jonathan Kagemann et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Differential expression of Ixodes ricinus salivary gland proteins in the presence of the Borrelia burgdorferi sensu lato complex

(2013) Violaine Cotté et al.   Journal of Proteomics

Microbial communities and symbionts in the hard tick Haemaphysalis longicornis (Acari: Ixodidae) from north China

(2013) Li-Meng Liu et al.   Parasites & Vectors

The ovarian transcriptome of the cattle tick, Rhipicephalus (Boophilus) microplus, feeding upon a bovine host infected with Babesia bovis

(2013) Andrew M Heekin et al.   Parasites & Vectors

Dicer-2 Processes Diverse Viral RNA Species

(2013) Leah R. Sabin et al.   PLoS One

Reciprocal Regulation of NF-kB (Relish) and Subolesin in the Tick Vector, Ixodes scapularis

(2013) Victoria Naranjo et al.   PLoS One

Vaccination with proteins involved in tick–pathogen interactions reduces vector infestations and pathogen infection

(2013) Octavio Merino et al.   VACCINE

Prevalence of Tick-Borne Pathogens in Adult Dermacentor spp. Ticks from Nine Collection Sites in France

(2013) S. Bonnet et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Discriminating Francisella tularensis and Francisella-like endosymbionts in Dermacentor reticulatus ticks: Evaluation of current molecular techniques

(2013) Lorraine Michelet et al.   VETERINARY MICROBIOLOGY

Crimean–Congo hemorrhagic fever virus utilizes a clathrin- and early endosome-dependent entry pathway

(2013) Aura R. Garrison et al.   VIROLOGY

Molecular mechanisms of cell-cell spread of intracellular bacterial pathogens

(2013) K. Ireton   Open Biology

Interaction of the tick immune system with transmitted pathogens

(2013) Ondřej Hajdušek et al.   Frontiers in Cellular and Infection Microbiology

Presence, genetic variability, and potential significance of “Candidatus Midichloria mitochondrii” in the lone star tick Amblyomma americanum

(2012) Amanda Jo Williams-Newkirk et al.   EXPERIMENTAL AND APPLIED ACAROLOGY

Borrelia burgdorferiand tick proteins supporting pathogen persistence in the vector

(2012) Faith Kung et al.   Future Microbiology

Babesia: A world emerging

(2012) Leonhard Schnittger et al.   INFECTION GENETICS AND EVOLUTION

Functional genomics studies of Rhipicephalus (Boophilus) annulatus ticks in response to infection with the cattle protozoan parasite, Babesia bigemina

(2012) Sandra Antunes et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

(2012) Justin D. Radolf et al.   NATURE REVIEWS MICROBIOLOGY

Analysis of Babesia bovis infection-induced gene expression changes in larvae from the cattle tick, Rhipicephalus (Boophilus) microplus

(2012) Andrew M Heekin et al.   Parasites & Vectors

Do the level of energy reserves, hydration status and Borrelia infection influence walking by Ixodes ricinus (Acari: Ixodidae) ticks?

(2012) C. HERRMANN et al.   PARASITOLOGY

Detection of Wolbachia in the Tick Ixodes ricinus is Due to the Presence of the Hymenoptera Endoparasitoid Ixodiphagus hookeri

(2012) Olivier Plantard et al.   PLoS One

Detection of Coxiella burnetii DNA in Wildlife and Ticks in Northern Queensland, Australia

(2012) A. Cooper et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Transovarial transmission of Borrelia spirochetes by Ixodes scapularis: A summary of the literature and recent observations

(2012) Lindsay Rollend et al.   Ticks and Tick-Borne Diseases

Epigenetics of Host–Pathogen Interactions: The Road Ahead and the Road Behind

(2012) Elena Gómez-Díaz et al.   PLoS Pathogens

Correlation of Borrelia burgdorferi Sensu Lato Prevalence in Questing Ixodes ricinus Ticks with Specific Abiotic Traits in the Western Palearctic

(2011) Agustín Estrada-Peña et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Detection of New Francisella-Like Tick Endosymbionts in Hyalomma spp. and Rhipicephalus spp. (Acari: Ixodidae) from Bulgaria

(2011) Ivan N. Ivanov et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Assessment of bacterial diversity in the cattle tick Rhipicephalus (Boophilus) microplus through tag-encoded pyrosequencing

(2011) Renato Andreotti et al.   BMC MICROBIOLOGY

A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent

(2011) Tim J. Schuijt et al.   Cell Host & Microbe

Endosymbiotic bacteria associated with nematodes, ticks and amoebae

(2011) Mark Taylor et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Distribution and molecular characterization of Wolbachia endosymbionts and filarial nematodes in Maryland populations of the lone star tick (Amblyomma americanum)

(2011) Xing Zhang et al.   FEMS MICROBIOLOGY ECOLOGY

Rapid Molecular Detection Methods for Arboviruses of Livestock of Importance to Northern Europe

(2011) Nicholas Johnson et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Cell death and infection: A double-edged sword for host and pathogen survival

(2011) Hiroshi Ashida et al.   JOURNAL OF CELL BIOLOGY

Expression of heat shock proteins and subolesin affects stress responses, Anaplasma phagocytophilum infection and questing behaviour in the tick, Ixodes scapularis

(2011) A. T. BUSBY et al.   MEDICAL AND VETERINARY ENTOMOLOGY

Male Killing and Incomplete Inheritance of a Novel Spiroplasma in the Moth Ostrinia zaguliaevi

(2011) Jun Tabata et al.   MICROBIAL ECOLOGY

Identification and Characterization of Ixodes scapularis Antigens That Elicit Tick Immunity Using Yeast Surface Display

(2011) Tim J. Schuijt et al.   PLoS One

Molecular Interactions that Enable Movement of the Lyme Disease Agent from the Tick Gut into the Hemolymph

(2011) Lili Zhang et al.   PLoS Pathogens

Molecular detection of Ehrlichia canis, Anaplasma bovis, Anaplasma platys, Candidatus Midichloria mitochondrii and Babesia canis vogeli in ticks from Israel

(2010) S. Harrus et al.   CLINICAL MICROBIOLOGY AND INFECTION

Detection of a new Arsenophonus-type bacterium in Canadian populations of the Rocky Mountain wood tick, Dermacentor andersoni

(2010) Shaun J. Dergousoff et al.   EXPERIMENTAL AND APPLIED ACAROLOGY

Anaplasma phagocytophilum induces Ixodes scapularis ticks to express an antifreeze glycoprotein gene that enhances their survival in the cold

(2010) Girish Neelakanta et al.   JOURNAL OF CLINICAL INVESTIGATION

Anaplasma phagocytophiluminduces actin phosphorylation to selectively regulate gene transcription inIxodes scapularisticks

(2010) Hameeda Sultana et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Survival of Ixodes ricinus (Acari: Ixodidae) Under Challenging Conditions of Temperature and Humidity Is Influenced by Borrelia burgdorferi sensu lato Infection

(2010) Coralie Herrmann et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Questing Ticks in Suburban Forest Are Infected by at Least Six Tick-Borne Pathogens

(2010) Caroline Reis et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Roles of Small GTPase Rac1 in the Regulation of Actin Cytoskeleton during Dengue Virus Infection

(2010) Jia-Li Wang et al.   PLoS Neglected Tropical Diseases

Tick Histamine Release Factor Is Critical for Ixodes scapularis Engorgement and Transmission of the Lyme Disease Agent

(2010) Jianfeng Dai et al.   PLoS Pathogens

Piroplasmids and ticks: a long-lasting intimate relationship

(2009) Monica Florin-Christensen   Frontiers in Bioscience-Landmark

Silencing of Host Cell CYBB Gene Expression by the Nuclear Effector AnkA of the Intracellular Pathogen Anaplasma phagocytophilum

(2009) J. C. Garcia-Garcia et al.   INFECTION AND IMMUNITY

Babesia and its hosts: adaptation to long-lasting interactions as a way to achieve efficient transmission

(2009) Alain Chauvin et al.   VETERINARY RESEARCH

Epigenetic Silencing of Host Cell Defense Genes Enhances Intracellular Survival of the Rickettsial Pathogen Anaplasma phagocytophilum

(2009) Jose C. Garcia-Garcia et al.   PLoS Pathogens

Overview: Ticks as vectors of pathogens that cause disease in humans and animals

(2008) Jose de la Fuente   Frontiers in Bioscience-Landmark

Crimean-Congo hemorrhagic fever virus entry and replication is clathrin-, pH- and cholesterol-dependent

(2008) M. Simon et al.   JOURNAL OF GENERAL VIROLOGY

Microbial communities and interactions in the lone star tick,Amblyomma americanum

(2008) K. CLAY et al.   MOLECULAR ECOLOGY

Amblyomma triste Koch, 1844 (Acari: Ixodidae): Hosts and seasonality of the vector of Rickettsia parkeri in Uruguay

(2008) J.M. Venzal et al.   VETERINARY PARASITOLOGY