Anaplasma phagocytophilumincreases the levels of histone modifying enzymes to inhibit cell apoptosis and facilitate pathogen infection in the tick vectorIxodes scapularis

Anaplasma phagocytophilum Uses Common Strategies for Infection of Ticks and Vertebrate Hosts

(2016) José de la Fuente et al.   TRENDS IN MICROBIOLOGY

Genomic insights into the Ixodes scapularis tick vector of Lyme disease

(2016) Monika Gulia-Nuss et al.   Nature Communications

MOZ and MORF acetyltransferases: Molecular interaction, animal development and human disease

(2015) Xiang-Jiao Yang   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Host-parasite interactions: an intimate epigenetic relationship

(2015) Kevin Cheeseman et al.   CELLULAR MICROBIOLOGY

Chromatin-bound bacterial effector ankyrin A recruits histone deacetylase 1 and modifies host gene expression

(2015) Kristen E. Rennoll-Bankert et al.   CELLULAR MICROBIOLOGY

Schistosome sirtuins as drug targets

(2015) Julien Lancelot et al.   Future Medicinal Chemistry

A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth

(2015) Alessia Peserico et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrated Metabolomics, Transcriptomics and Proteomics Identifies Metabolic Pathways Affected byAnaplasma phagocytophilumInfection in Tick Cells

(2015) Margarita Villar et al.   MOLECULAR & CELLULAR PROTEOMICS

Sound of silence: the properties and functions of repressive Lys methyltransferases

(2015) Chiara Mozzetta et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HDAC8: a multifaceted target for therapeutic interventions

(2015) Alokta Chakrabarti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Tissue- and time-dependent transcription in Ixodes ricinus salivary glands and midguts when blood feeding on the vertebrate host

(2015) Michalis Kotsyfakis et al.   Scientific Reports

Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis

(2015) Nieves Ayllón et al.   PLoS Genetics

Global DNA methylation changes and differential gene expression in Anaplasma phagocytophilum-infected human neutrophils

(2015) Sara H. G. Sinclair et al.   Clinical Epigenetics

Structures and functions of insect arylalkylamine N-acetyltransferase (iaaNAT); a key enzyme for physiological and behavioral switch in arthropods

(2015) Susumu Hiragaki et al.   Frontiers in Physiology

Chromatin Dynamics in Vivo: A Game of Musical Chairs

(2015) Daniël Melters et al.   Genes

HDAC8, A Potential Therapeutic Target for the Treatment of Malignant Peripheral Nerve Sheath Tumors (MPNST)

(2015) Gonzalo Lopez et al.   PLoS One

Nuclease Tudor-SN Is Involved in Tick dsRNA-Mediated RNA Interference and Feeding but Not in Defense against Flaviviral or Anaplasma phagocytophilum Rickettsial Infection

(2015) Nieves Ayllón et al.   PLoS One

Pathogens Hijack the Epigenome

(2014) Natalie C. Silmon de Monerri et al.   AMERICAN JOURNAL OF PATHOLOGY

Regulation of histone modifying enzymes by the ubiquitin–proteasome system

(2014) Chunbin Zou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cryptosporidium parvum induces SIRT1 expression in host epithelial cells through downregulating let-7i

(2014) Hongguan Xie et al.   HUMAN IMMUNOLOGY

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes

(2014) J. M. Hill et al.   Science Translational Medicine

Release and activity of histone in diseases

(2014) R Chen et al.   Cell Death & Disease

CD86 expression as a surrogate cellular biomarker for pharmacological inhibition of the histone demethylase lysine-specific demethylase 1

(2013) James T. Lynch et al.   ANALYTICAL BIOCHEMISTRY

Anaplasma phagocytophilum Inhibits Apoptosis and Promotes Cytoskeleton Rearrangement for Infection of Tick Cells

(2013) Nieves Ayllón et al.   INFECTION AND IMMUNITY

The E3 Ubiquitin Ligase XIAP Restricts Anaplasma phagocytophilum Colonization of Ixodes scapularis Ticks

(2013) Maiara S. Severo et al.   JOURNAL OF INFECTIOUS DISEASES

The 2.5 Å Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD+) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition

(2013) Xun Zhao et al.   JOURNAL OF MEDICINAL CHEMISTRY

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Jumonji C Domain Protein JMJ705-Mediated Removal of Histone H3 Lysine 27 Trimethylation Is Involved in Defense-Related Gene Activation in Rice

(2013) T. Li et al.   PLANT CELL

Tryptogalinin Is a Tick Kunitz Serine Protease Inhibitor with a Unique Intrinsic Disorder

(2013) James J. Valdés et al.   PLoS One

Knockdown of Selenocysteine-Specific Elongation Factor in Amblyomma maculatum Alters the Pathogen Burden of Rickettsia parkeri with Epigenetic Control by the Sin3 Histone Deacetylase Corepressor Complex

(2013) Steven W. Adamson et al.   PLoS One

A Role for SIRT2-Dependent Histone H3K18 Deacetylation in Bacterial Infection

(2013) H. A. Eskandarian et al.   SCIENCE

Schistosoma mansoni Sirtuins: Characterization and Potential as Chemotherapeutic Targets

(2013) Julien Lancelot et al.   PLoS Neglected Tropical Diseases

Anaplasma phagocytophilum—a widespread multi-host pathogen with highly adaptive strategies

(2013) Snorre Stuen et al.   Frontiers in Cellular and Infection Microbiology

Histone acetylation mediates epigenetic regulation of transcriptional reprogramming in insects during metamorphosis, wounding and infection

(2012) Krishnendu Mukherjee et al.   Frontiers in Zoology

Resolution-by-proxy: a simple measure for assessing and comparing the overall quality of NMR protein structures

(2012) Mark Berjanskii et al.   JOURNAL OF BIOMOLECULAR NMR

p300 Exerts an Epigenetic Role in Chronic Neuropathic Pain through its Acetyltransferase Activity in Rats following Chronic Constriction Injury (CCI)

(2012) Xiao-Yan Zhu et al.   Molecular Pain

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

EvolView, an online tool for visualizing, annotating and managing phylogenetic trees

(2012) Huangkai Zhang et al.   NUCLEIC ACIDS RESEARCH

Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development

(2012) P. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic reprogramming by class I and II histone deacetylases

(2012) Maria M. Mihaylova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Epigenetics of Host–Pathogen Interactions: The Road Ahead and the Road Behind

(2012) Elena Gómez-Díaz et al.   PLoS Pathogens

KSHV PAN RNA Associates with Demethylases UTX and JMJD3 to Activate Lytic Replication through a Physical Interaction with the Virus Genome

(2012) Cyprian C. Rossetto et al.   PLoS Pathogens

Mechanisms of Obligatory Intracellular Infection with Anaplasma phagocytophilum

(2011) Y. Rikihisa   CLINICAL MICROBIOLOGY REVIEWS

Structure and Biochemical Functions of SIRT6

(2011) Patricia W. Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microreview: Type IV secretion in the obligatory intracellular bacterium Anaplasma phagocytophilum

(2010) Yasuko Rikihisa et al.   CELLULAR MICROBIOLOGY

Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294

(2010) Kenichi Imai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anaplasma phagocytophilum APH_0032 is expressed late during infection and localizes to the pathogen-occupied vacuolar membrane

(2010) Bernice Huang et al.   MICROBIAL PATHOGENESIS

Lessons on longevity from budding yeast

(2010) Matt Kaeberlein   NATURE

Epigenetic modifications and human disease

(2010) Anna Portela et al.   NATURE BIOTECHNOLOGY

Anaplasma phagocytophilum and Ehrlichia chaffeensis: subversive manipulators of host cells

(2010) Yasuko Rikihisa   NATURE REVIEWS MICROBIOLOGY

Arabidopsis Histone Methyltransferase SET DOMAIN GROUP8 Mediates Induction of the Jasmonate/Ethylene Pathway Genes in Plant Defense Response to Necrotrophic Fungi

(2010) A. Berr et al.   PLANT PHYSIOLOGY

Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer

(2010) Daniel Herranz et al.   Nature Communications

Histone Methylation by NUE, a Novel Nuclear Effector of the Intracellular Pathogen Chlamydia trachomatis

(2010) Meghan E. Pennini et al.   PLoS Pathogens

Moz and Retinoic Acid Coordinately Regulate H3K9 Acetylation, Hox Gene Expression, and Segment Identity

(2009) Anne K. Voss et al.   DEVELOPMENTAL CELL

Red wine triggers cell death and thioredoxin reductase inhibition: Effects beyond resveratrol and SIRT1

(2009) Karolina Wallenborg et al.   EXPERIMENTAL CELL RESEARCH

An operational definition of epigenetics

(2009) S. L. Berger et al.   GENES & DEVELOPMENT

Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes

(2009) Lei Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin/Sir2 phylogeny, evolutionary considerations and structural conservation

(2009) Sebastian Greiss et al.   MOLECULES AND CELLS

Molecular events involved in cellular invasion by Ehrlichia chaffeensis and Anaplasma phagocytophilum

(2009) Yasuko Rikihisa   VETERINARY PARASITOLOGY

Epigenetic Silencing of Host Cell Defense Genes Enhances Intracellular Survival of the Rickettsial Pathogen Anaplasma phagocytophilum

(2009) Jose C. Garcia-Garcia et al.   PLoS Pathogens

Recent developments in the MAFFT multiple sequence alignment program

(2008) K. Katoh et al.   BRIEFINGS IN BIOINFORMATICS

Overview: Ticks as vectors of pathogens that cause disease in humans and animals

(2008) Jose de la Fuente   Frontiers in Bioscience-Landmark

Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes

(2008) M. Ullah et al.   MOLECULAR AND CELLULAR BIOLOGY

Inoculation of White-Tailed Deer (Odocoileus Virginianus) with Ap-V1 Or NY-18 Strains of Anaplasma Phagocytophilum and Microscopic Demonstration of Ap-V1 In Ixodes Scapularis Adults that Acquired Infection from Deer as Nymphs

(2008) Mason V. Reichard et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

QMEAN: A comprehensive scoring function for model quality assessment

(2007) Pascal Benkert et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS