Formation of the Legionella Replicative Compartment at the Crossroads of Retrograde Trafficking

Comparative Proteomics of Purified Pathogen Vacuoles Correlates Intracellular Replication ofLegionella pneumophilawith the Small GTPase Ras-related protein 1 (Rap1)

(2017) Johanna Schmölders et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5

(2017) Kevin Bärlocher et al.   Nature Communications

Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein

(2017) Jianhua Zhao et al.   PLoS Pathogens

Structural Mechanism for Cargo Recognition by the Retromer Complex

(2016) María Lucas et al.   CELL

Legionella pneumophila, armed to the hilt: justifying the largest arsenal of effectors in the bacterial world

(2016) Alexander W Ensminger   CURRENT OPINION IN MICROBIOLOGY

Bidirectional traffic between the Golgi and the endosomes – machineries and regulation

(2016) Cinzia Progida et al.   JOURNAL OF CELL SCIENCE

Probable Person-to-Person Transmission of Legionnaires’ Disease

(2016) Ana M. Correia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Subversion of Retrograde Trafficking by Translocated Pathogen Effectors

(2016) Nicolas Personnic et al.   TRENDS IN MICROBIOLOGY

Structural and mechanistic insights into regulation of the retromer coat by TBC1d5

(2016) Da Jia et al.   Nature Communications

The role of the Lowe syndrome protein OCRL in the endocytic pathway

(2015) Shruti Sharma et al.   BIOLOGICAL CHEMISTRY

Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection

(2015) Kathleen M. Mirrashidi et al.   Cell Host & Microbe

Formation of a pathogen vacuole according toLegionella pneumophila: how to kill one bird with many stones

(2015) Ivo Finsel et al.   CELLULAR MICROBIOLOGY

Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis

(2015) Andreas Jeschke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Proteome of the Isolated Chlamydia trachomatis Containing Vacuole Reveals a Complex Trafficking Platform Enriched for Retromer Components

(2015) Lukas Aeberhard et al.   PLoS Pathogens

Purification and proteomics of pathogen-modified vacuoles and membranes

(2015) Jo-Ana Herweg et al.   Frontiers in Cellular and Infection Microbiology

Subversion of Cell-Autonomous Immunity and Cell Migration by Legionella pneumophila Effectors

(2015) Sylvia Simon et al.   Frontiers in Immunology

A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer

(2014) M. Gallon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

From endosomes to the trans-Golgi network

(2014) Lei Lu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Live-Cell Imaging of Phosphoinositide Dynamics and Membrane Architecture during Legionella Infection

(2014) S. Weber et al.   mBio

Retromer: A Master Conductor of Endosome Sorting

(2014) C. Burd et al.   Cold Spring Harbor Perspectives in Biology

Rab Proteins and the Compartmentalization of the Endosomal System

(2014) A. Wandinger-Ness et al.   Cold Spring Harbor Perspectives in Biology

A Rab-Centric Perspective of Bacterial Pathogen-Occupied Vacuoles

(2013) Racquel Kim Sherwood et al.   Cell Host & Microbe

The Legionella Effector RidL Inhibits Retrograde Trafficking to Promote Intracellular Replication

(2013) Ivo Finsel et al.   Cell Host & Microbe

Snx3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation

(2013) Caiyong Chen et al.   Cell Metabolism

The natural alternative: protozoa as cellular models forLegionellainfection

(2013) Christine Hoffmann et al.   CELLULAR MICROBIOLOGY

Functional analysis of novel Rab GTPases identified in the proteome of purifiedLegionella-containing vacuoles from macrophages

(2013) Christine Hoffmann et al.   CELLULAR MICROBIOLOGY

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

A mechanism for retromer endosomal coat complex assembly with cargo

(2013) M. S. Harrison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host Pathways Important for Coxiella burnetii Infection Revealed by Genome-Wide RNA Interference Screening

(2013) J. A. McDonough et al.   mBio

Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection

(2013) Eva Rothmeier et al.   PLoS Pathogens

The Legionella pneumophila Effector DrrA Is Sufficient to Stimulate SNARE-Dependent Membrane Fusion

(2012) Kohei Arasaki et al.   Cell Host & Microbe

Molecular basis for SNX-BAR-mediated assembly of distinct endosomal sorting tubules

(2012) Jan R T van Weering et al.   EMBO JOURNAL

The retromer complex - endosomal protein recycling and beyond

(2012) M. N. J. Seaman   JOURNAL OF CELL SCIENCE

Coordination between RAB GTPase and phosphoinositide regulation and functions

(2012) Steve Jean et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Salmonella Inhibits Retrograde Trafficking of Mannose-6-Phosphate Receptors and Lysosome Function

(2012) K. McGourty et al.   SCIENCE

Dynamics of Rab7b-Dependent Transport of Sorting Receptors

(2012) Cinzia Progida et al.   TRAFFIC

Secretive Bacterial Pathogens and the Secretory Pathway

(2012) Hubert Hilbi et al.   TRAFFIC

Insights into the PX (phox-homology) domain and SNX (sorting nexin) protein families: structures, functions and roles in disease

(2011) Rohan D. Teasdale et al.   BIOCHEMICAL JOURNAL

Covalent Coercion by Legionella pneumophila

(2011) Aymelt Itzen et al.   Cell Host & Microbe

A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1

(2011) Xiaomin Hou et al.   EMBO JOURNAL

OCRL controls trafficking through early endosomes via PtdIns4,5P2-dependent regulation of endosomal actin

(2011) Mariella Vicinanza et al.   EMBO JOURNAL

The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway

(2011) Christopher J. Noakes et al.   MOLECULAR BIOLOGY OF THE CELL

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

Sorting nexins provide diversity for retromer-dependent trafficking events

(2011) Peter J. Cullen et al.   NATURE CELL BIOLOGY

Retrograde Transport: Two (or More) Roads Diverged in an Endosomal Tree?

(2011) Ludger Johannes et al.   TRAFFIC

Legionellaspp. outdoors: colonization, communication and persistence

(2011) Hubert Hilbi et al.   Environmental Microbiology Reports

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Molecular Pathogenesis of Infections Caused by Legionella pneumophila

(2010) H. J. Newton et al.   CLINICAL MICROBIOLOGY REVIEWS

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

(2010) M. E. Harbour et al.   JOURNAL OF CELL SCIENCE

Rab7b controls trafficking from endosomes to the TGN

(2010) C. Progida et al.   JOURNAL OF CELL SCIENCE

Legionella pneumophila Promotes Functional Interactions between Plasma Membrane Syntaxins and Sec22b

(2010) Kohei Arasaki et al.   TRAFFIC

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

The BAR Domain Superfamily: Membrane-Molding Macromolecules

(2009) Adam Frost et al.   CELL

The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network

(2009) Thomas Wassmer et al.   DEVELOPMENTAL CELL

A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting

(2009) Timothy S. Gomez et al.   DEVELOPMENTAL CELL

A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism

(2009) Yuxin Mao et al.   EMBO JOURNAL

Proteomic analysis of Legionella-containing phagosomes isolated from Dictyostelium

(2009) Olga Shevchuk et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

(2009) M. N. J. Seaman et al.   JOURNAL OF CELL SCIENCE

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Proteome Analysis of Legionella Vacuoles Purified by Magnetic Immunoseparation Reveals Secretory and Endosomal GTPases

(2009) Simon Urwyler et al.   TRAFFIC

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth ofLegionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE

(2008) Stefan S. Weber et al.   CELLULAR MICROBIOLOGY

Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7

(2008) Raul Rojas et al.   JOURNAL OF CELL BIOLOGY

Large Scale Screening for Novel Rab Effectors Reveals Unexpected Broad Rab Binding Specificity

(2008) Mitsunori Fukuda et al.   MOLECULAR & CELLULAR PROTEOMICS

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY