The natural alternative: protozoa as cellular models forLegionellainfection

The Legionella Effector RidL Inhibits Retrograde Trafficking to Promote Intracellular Replication

(2013) Ivo Finsel et al.   Cell Host & Microbe

Multiple Legionella pneumophila Type II Secretion Substrates, Including a Novel Protein, Contribute to Differential Infection of the Amoebae Acanthamoeba castellanii, Hartmannella vermiformis, and Naegleria lovaniensis

(2013) Jessica Y. Tyson et al.   INFECTION AND IMMUNITY

TheLegionella pneumophilaDot/Icm-secreted Effector PlcC/CegC1 Together with PlcA and PlcB Promotes Virulence and Belongs to a Novel Zinc Metallophospholipase C Family Present in Bacteria and Fungi

(2013) Philipp Aurass et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exploring Anti-Bacterial Compounds against Intracellular Legionella

(2013) Christopher F. Harrison et al.   PLoS One

Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal

(2013) Z. Lifshitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection

(2013) Eva Rothmeier et al.   PLoS Pathogens

Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling

(2013) Michael Clarke et al.   GENOME BIOLOGY

Domain organization of Legionella effector SetA

(2012) Thomas Jank et al.   CELLULAR MICROBIOLOGY

TheLegionella pneumophilaorphan sensor kinase LqsT regulates competence and pathogen-host interactions as a component of the LAI-1 circuit

(2012) Aline Kessler et al.   ENVIRONMENTAL MICROBIOLOGY

Zinc Metalloproteinase ProA Directly ActivatesLegionella pneumophilaPlaC Glycerophospholipid:cholesterol Acyltransferase

(2012) Christina Lang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nramp (Slc11) proteins regulate development, resistance to pathogenic bacteria and iron homeostasis in Dictyostelium discoideum

(2012) Barbara Peracino et al.   JOURNAL OF CELL SCIENCE

Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase

(2012) F. Hsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deep sequencing defines the transcriptional map ofL. pneumophilaand identifies growth phase-dependent regulated ncRNAs implicated in virulence

(2012) Tobias Sahr et al.   RNA Biology

The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation

(2012) A. Choy et al.   SCIENCE

Secretive Bacterial Pathogens and the Secretory Pathway

(2012) Hubert Hilbi et al.   TRAFFIC

VipD of Legionella pneumophila Targets Activated Rab5 and Rab22 to Interfere with Endosomal Trafficking in Macrophages

(2012) Bonsu Ku et al.   PLoS Pathogens

Covalent Coercion by Legionella pneumophila

(2011) Aymelt Itzen et al.   Cell Host & Microbe

Lcl of Legionella pneumophila Is an Immunogenic GAG Binding Adhesin That Promotes Interactions with Lung Epithelial Cells and Plays a Crucial Role in Biofilm Formation

(2011) Carla Duncan et al.   INFECTION AND IMMUNITY

Sequencing Illustrates the Transcriptional Response of Legionella pneumophila during Infection and Identifies Seventy Novel Small Non-Coding RNAs

(2011) Barbara A. Weissenmayer et al.   PLoS One

Comprehensive Identification of Protein Substrates of the Dot/Icm Type IV Transporter of Legionella pneumophila

(2011) Wenhan Zhu et al.   PLoS One

Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion

(2011) T. J. O'Connor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Legionellaspp. outdoors: colonization, communication and persistence

(2011) Hubert Hilbi et al.   Environmental Microbiology Reports

Legionella Pneumophila Transcriptome during Intracellular Multiplication in Human Macrophages

(2011) Sébastien P. Faucher et al.   Frontiers in Microbiology

Innate Immunity to Legionella Pneumophila

(2011) Liliana M. Massis et al.   Frontiers in Microbiology

Anchors for Effectors: Subversion of Phosphoinositide Lipids by Legionella

(2011) Hubert Hilbi et al.   Frontiers in Microbiology

Modulation of Host Cell Function byLegionella pneumophilaType IV Effectors

(2010) Andree Hubber et al.   Annual Review of Cell and Developmental Biology

Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila

(2010) Sze Man Tung et al.   CELLULAR MICROBIOLOGY

Molecular Pathogenesis of Infections Caused by Legionella pneumophila

(2010) H. J. Newton et al.   CLINICAL MICROBIOLOGY REVIEWS

The autoinducer synthase LqsA and putative sensor kinase LqsS regulate phagocyte interactions, extracellular filaments and a genomic island of Legionella pneumophila

(2010) André Tiaden et al.   ENVIRONMENTAL MICROBIOLOGY

Phosphoinositides differentially regulate bacterial uptake and Nramp1-induced resistance to Legionella infection in Dictyostelium

(2010) Barbara Peracino et al.   JOURNAL OF CELL SCIENCE

Inhibition of Host Vacuolar H+-ATPase Activity by a Legionella pneumophila Effector

(2010) Li Xu et al.   PLoS Pathogens

bdhA-patD Operon as a Virulence Determinant, Revealed by a Novel Large-Scale Approach for Identification of Legionella pneumophila Mutants Defective for Amoeba Infection

(2009) P. Aurass et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

ALegionellaeffector acquired from protozoa is involved in sphingolipids metabolism and is targeted to the host cell mitochondria

(2009) Elena Degtyar et al.   CELLULAR MICROBIOLOGY

Modulation of caspases and their non-apoptotic functions byLegionella pneumophila

(2009) Amal O. Amer   CELLULAR MICROBIOLOGY

Temporal and spatial trigger of post-exponential virulence-associated regulatory cascades byLegionella pneumophilaafter bacterial escape into the host cell cytosol

(2009) Maëlle Molmeret et al.   ENVIRONMENTAL MICROBIOLOGY

Proteomic analysis of Legionella-containing phagosomes isolated from Dictyostelium

(2009) Olga Shevchuk et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Phospholipase PlaB ofLegionella pneumophilaRepresents a Novel Lipase Family

(2009) Jennifer Bender et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathogen trafficking pathways and host phosphoinositide metabolism

(2009) Stefan S. Weber et al.   MOLECULAR MICROBIOLOGY

A Legionella type IV effector activates the NF- B pathway by phosphorylating the I B family of inhibitors

(2009) J. Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proteome Analysis of Legionella Vacuoles Purified by Magnetic Immunoseparation Reveals Secretory and Endosomal GTPases

(2009) Simon Urwyler et al.   TRAFFIC

Temperature-Dependent Parasitic Relationship between Legionella pneumophila and a Free-Living Amoeba (Acanthamoeba castellanii)

(2008) A. Ohno et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Packaging of Live Legionella pneumophila into Pellets Expelled by Tetrahymena spp. Does Not Require Bacterial Replication and Depends on a Dot/Icm-Mediated Survival Mechanism

(2008) S. G. Berk et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

TheLegionella pneumophilaphosphatidylinositol-4 phosphate-binding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replication-permissive vacuole

(2008) Curdin Ragaz et al.   CELLULAR MICROBIOLOGY

The inositol polyphosphate 5-phosphatase OCRL1 restricts intracellular growth ofLegionella, localizes to the replicative vacuole and binds to the bacterial effector LpnE

(2008) Stefan S. Weber et al.   CELLULAR MICROBIOLOGY

Significant Role for ladC in Initiation of Legionella pneumophila Infection

(2008) H. J. Newton et al.   INFECTION AND IMMUNITY

Heterogeneity in chlorine susceptibility forLegionella pneumophilareleased fromAcanthamoebaandHartmannella

(2008) C.-W. Chang et al.   JOURNAL OF APPLIED MICROBIOLOGY

Synergistic Contribution of the Legionella pneumophila lqs Genes to Pathogen-Host Interactions

(2008) A. Tiaden et al.   JOURNAL OF BACTERIOLOGY

Passage through Tetrahymena tropicalis Triggers a Rapid Morphological Differentiation in Legionella pneumophila

(2008) G. Faulkner et al.   JOURNAL OF BACTERIOLOGY

TheLegionellaAutoinducer Synthase LqsA Produces an α-Hydroxyketone Signaling Molecule

(2008) Thomas Spirig et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab1 Guanine Nucleotide Exchange Factor SidM Is a Major Phosphatidylinositol 4-Phosphate-binding Effector Protein ofLegionella pneumophila

(2008) Eva Brombacher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Legionella pneumophila replication vacuole: making a cosy niche inside host cells

(2008) Ralph R. Isberg et al.   NATURE REVIEWS MICROBIOLOGY

Icm/Dot-dependent upregulation of phagocytosis by Legionella pneumophila

(2003) Hubert Hilbi et al.   MOLECULAR MICROBIOLOGY