A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Multiple Host Proteins That Function in Phosphatidylinositol-4-Phosphate Metabolism Are Recruited to the Chlamydial Inclusion

(2010) A. M. Moorhead et al.   INFECTION AND IMMUNITY

Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1

(2010) Laura E. Swan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for Rab GTPase recognition and endosome tethering by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)

(2010) A. Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GTPases involved in vesicular trafficking: Structures and mechanisms

(2010) Aymelt Itzen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

(2009) Lisa M. Ooms et al.   BIOCHEMICAL JOURNAL

A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism

(2009) Yuxin Mao et al.   EMBO JOURNAL

Lowe syndrome patient fibroblasts display Ocrl1-specific cell migration defects that cannot be rescued by the homologous Inpp5b phosphatase

(2009) Brian G. Coon et al.   HUMAN MOLECULAR GENETICS

Differential Clathrin Binding and Subcellular Localization of OCRL1 Splice Isoforms

(2009) Rawshan Choudhury et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

OCRL1 Mutations in Dent 2 Patients Suggest a Mechanism for Phenotypic Variability

(2009) Antony E. Shrimpton et al.   NEPHRON PHYSIOLOGY

Structural Basis for Recruitment of Rab6-Interacting Protein 1 to Golgi via a RUN Domain

(2009) Rosario Recacha et al.   STRUCTURE

Structural Mechanisms for Regulation of Membrane Traffic by Rab GTPases

(2009) Meng-Tse Gabe Lee et al.   TRAFFIC

Rab and Arl GTPase Family Members Cooperate in the Localization of the Golgin GCC185

(2008) Alondra Schweizer Burguete et al.   CELL

Fanconi or not Fanconi? Lowe Syndrome Revisited

(2008) R. Kleta   Clinical Journal of the American Society of Nephrology

Large Scale Screening for Novel Rab Effectors Reveals Unexpected Broad Rab Binding Specificity

(2008) Mitsunori Fukuda et al.   MOLECULAR & CELLULAR PROTEOMICS

Coordinated protein sorting, targeting and distribution in polarized cells

(2008) Ira Mellman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chaperone-assisted production of active human Rab8A GTPase in Escherichia coli

(2008) Nathalie Bleimling et al.   PROTEIN EXPRESSION AND PURIFICATION

Structural Basis for the Exclusive Specificity of Slac2-a/Melanophilin for the Rab27 GTPases

(2008) Mutsuko Kukimoto-Niino et al.   STRUCTURE

Elucidation of Rab27 Recruitment by Its Effectors: Structure of Rab27a Bound to Exophilin4/Slp2-a

(2008) Leonard M.G. Chavas et al.   STRUCTURE