Box C/D small nucleolar RNA genes and the Prader-Willi syndrome: a complex interplay

Oligonucleotide‐induced alternative splicing of serotonin 2C receptor reduces food intake

(2016) Zhaiyi Zhang et al.   EMBO Molecular Medicine

Working-for-Food Behaviors: A Preclinical Study in Prader-Willi Mutant Mice

(2016) G. Lassi et al.   GENETICS

The phenotypic spectrum of Schaaf-Yang syndrome: 18 new affected individuals from 14 families

(2016) Michael D. Fountain et al.   GENETICS IN MEDICINE

Rpl13a small nucleolar RNAs regulate systemic glucose metabolism

(2016) Jiyeon Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Deficiency in prohormone convertase PC1 impairs prohormone processing in Prader-Willi syndrome

(2016) Lisa C. Burnett et al.   JOURNAL OF CLINICAL INVESTIGATION

Unusual Processing Generates SPA LncRNAs that Sequester Multiple RNA Binding Proteins

(2016) Huang Wu et al.   MOLECULAR CELL

Global Mapping of Human RNA-RNA Interactions

(2016) Eesha Sharma et al.   MOLECULAR CELL

Mutations in SNORD118 cause the cerebral microangiopathy leukoencephalopathy with calcifications and cysts

(2016) Emma M Jenkinson et al.   NATURE GENETICS

Profiling of 2′-O-Me in human rRNA reveals a subset of fractionally modified positions and provides evidence for ribosome heterogeneity

(2016) Nicolai Krogh et al.   NUCLEIC ACIDS RESEARCH

Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing

(2016) Marina Falaleeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory links between imprinted genes: evolutionary predictions and consequences

(2016) Manus M. Patten et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

(2016) Katherine E. Sloan et al.   RNA Biology

Assembly and trafficking of box C/D and H/ACA snoRNPs

(2016) Séverine Massenet et al.   RNA Biology

Deletion of the Snord116/SNORD116 Alters Sleep in Mice and Patients with Prader-Willi Syndrome

(2016) Glenda Lassi et al.   SLEEP

Induced pluripotent stem cells (iPSC) created from skin fibroblasts of patients with Prader-Willi syndrome (PWS) retain the molecular signature of PWS

(2016) Lisa C. Burnett et al.   Stem Cell Research

The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis

(2016) Jean-Louis Langhendries et al.   Oncotarget

Maternal transcription of non-protein coding RNAs from the PWS-critical region rescues growth retardation in mice

(2016) Timofey S. Rozhdestvensky et al.   Scientific Reports

Increased alternate splicing of Htr2c in a mouse model for Prader-Willi syndrome leads disruption of 5HT2C receptor mediated appetite

(2016) Alastair S. Garfield et al.   Molecular Brain

Deletion of the Snord116/SNORD116 Alters Sleep in Mice and Patients with Prader-Willi Syndrome

(2016) Glenda Lassi et al.   SLEEP

Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome

(2016) Ee-Cheng Khor et al.   PLoS One

Snord116 is critical in the regulation of food intake and body weight

(2016) Yue Qi et al.   Scientific Reports

Translating the Genome in Time and Space: Specialized Ribosomes, RNA Regulons, and RNA-Binding Proteins

(2015) Zhen Shi et al.   Annual Review of Cell and Developmental Biology

Ribosomopathies: how a common root can cause a tree of pathologies

(2015) Nadia Danilova et al.   Disease Models & Mechanisms

SNORD116 and SNORD115 change expression of multiple genes and modify each other's activity

(2015) Marina Falaleeva et al.   GENE

The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer

(2015) Zurab Siprashvili et al.   NATURE GENETICS

Behavioural characteristics of the Prader–Willi syndrome related biallelic Snord116 mouse model

(2015) Jerzy Zieba et al.   NEUROPEPTIDES

The early days of RNomics

(2015) Alexander Hüttenhofer   RNA

The emerging landscape of small nucleolar RNAs in cell biology

(2015) Fabien Dupuis-Sandoval et al.   Wiley Interdisciplinary Reviews-RNA

Phenotypic Outcomes of Imprinted Gene Models in Mice: Elucidation of Pre- and Postnatal Functions of Imprinted Genes

(2014) Mary A.M. Cleaton et al.   Annual Review of Genomics and Human Genetics

Species-specific alternative splicing leads to unique expression of sno-lncRNAs

(2014) Xiao-Ou Zhang et al.   BMC GENOMICS

Abnormal Response to the Anorexic Effect of GHS-R Inhibitors and Exenatide in MaleSnord116Deletion Mouse Model for Prader-Willi Syndrome

(2014) Dahe Lin et al.   ENDOCRINOLOGY

Highly restricted deletion of the SNORD116 region is implicated in Prader–Willi Syndrome

(2014) Eric Bieth et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Prevention of 5-hydroxytryptamine2Creceptor RNA editing and alternate splicing in C57BL/6 mice activates the hypothalamic-pituitary-adrenal axis and alters mood

(2014) Vincent Bombail et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Reactivation of maternal SNORD116 cluster via SETDB1 knockdown in Prader-Willi syndrome iPSCs

(2014) E. Cruvinel et al.   HUMAN MOLECULAR GENETICS

Temple syndrome: improving the recognition of an underdiagnosed chromosome 14 imprinting disorder: an analysis of 51 published cases

(2014) Yiannis Ioannides et al.   JOURNAL OF MEDICAL GENETICS

The noncoding RNA IPW regulates the imprinted DLK1-DIO3 locus in an induced pluripotent stem cell model of Prader-Willi syndrome

(2014) Yonatan Stelzer et al.   NATURE GENETICS

Rapid Birth-and-Death Evolution of Imprinted snoRNAs in the Prader-Willi Syndrome Locus: Implications for Neural Development in Euarchontoglires

(2014) Yi-Jun Zhang et al.   PLoS One

The snoRNA MBII-52 Regulates Cocaine-Induced Conditioned Place Preference and Locomotion in Mice

(2014) Hongjie Chen et al.   PLoS One

Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9

(2014) Jinxiong Han et al.   RNA Biology

Genomic Imprinting in Mammals

(2014) D. P. Barlow et al.   Cold Spring Harbor Perspectives in Biology

Differential regulation of non-protein coding RNAs from Prader-Willi Syndrome locus

(2014) Chenna R. Galiveti et al.   Scientific Reports

Considerations when investigating lncRNA function in vivo

(2014) Andrew R Bassett et al.   eLife

Mouse models of Prader–Willi Syndrome: A systematic review

(2013) Sandrina Bervini et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Imprinted expression of UBE3A in non-neuronal cells from a Prader–Willi syndrome patient with an atypical deletion

(2013) Kristen Martins-Taylor et al.   HUMAN MOLECULAR GENETICS

A Prader–Willi locus lncRNA cloud modulates diurnal genes and energy expenditure

(2013) Weston T. Powell et al.   HUMAN MOLECULAR GENETICS

Box C/D Small Nucleolar RNA (snoRNA) U60 Regulates Intracellular Cholesterol Trafficking

(2013) Katrina A. Brandis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matching of Soulmates: Coevolution of snoRNAs and Their Targets

(2013) S. Kehr et al.   MOLECULAR BIOLOGY AND EVOLUTION

R-loop formation atSnord116mediates topotecan inhibition ofUbe3a-antisenseand allele-specific chromatin decondensation

(2013) Weston T. Powell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Truncation of Ube3a-ATS Unsilences Paternal Ube3a and Ameliorates Behavioral Defects in the Angelman Syndrome Mouse Model

(2013) Linyan Meng et al.   PLoS Genetics

Serotonin2C receptors and drug addiction: focus on cocaine

(2013) Céline Devroye et al.   EXPERIMENTAL BRAIN RESEARCH

The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis

(2012) Leonidas Benetatos et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Small regulatory RNAs controlled by genomic imprinting and their contribution to human disease

(2012) Michael Girardot et al.   Epigenetics

Prader-Willi syndrome

(2012) Suzanne B. Cassidy et al.   GENETICS IN MEDICINE

Hypothalamic expression of snoRNA Snord116 is consistent with a link to the hyperphagia and obesity symptoms of Prader–Willi syndrome

(2012) Qian Zhang et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Long Noncoding RNAs with snoRNA Ends

(2012) Qing-Fei Yin et al.   MOLECULAR CELL

RNA splicing and editing modulation of 5-HT2C receptor function: relevance to anxiety and aggression in VGV mice

(2012) C B P Martin et al.   MOLECULAR PSYCHIATRY

Specialized ribosomes: a new frontier in gene regulation and organismal biology

(2012) Shifeng Xue et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The SNORD115 (H/MBII-52) and SNORD116 (H/MBII-85) gene clusters at the imprinted Prader-Willi locus generate canonical box C/D snoRNAs

(2012) M.-L. Bortolin-Cavaille et al.   NUCLEIC ACIDS RESEARCH

RNAs of the human chromosome 15q11-q13 imprinted region

(2012) Stormy J. Chamberlain   Wiley Interdisciplinary Reviews-RNA

Do repeated arrays of regulatory small-RNA genes elicit genomic imprinting?

(2011) Stéphane Labialle et al.   BIOESSAYS

Genomic imprinting: the emergence of an epigenetic paradigm

(2011) Anne C. Ferguson-Smith   NATURE REVIEWS GENETICS

Loss of ribosomal RNA modification causes developmental defects in zebrafish

(2011) Sayomi Higa-Nakamine et al.   NUCLEIC ACIDS RESEARCH

Direct cloning of double-stranded RNAs from RNase protection analysis reveals processing patterns of C/D box snoRNAs and provides evidence for widespread antisense transcript expression

(2011) Manli Shen et al.   NUCLEIC ACIDS RESEARCH

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA

(2011) Nicholas J. Watkins et al.   Wiley Interdisciplinary Reviews-RNA

Prader-Willi syndrome and Angelman syndrome

(2010) Karin Buiting   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

PLEXY: efficient target prediction for box C/D snoRNAs

(2010) Stephanie Kehr et al.   BIOINFORMATICS

Paternally inherited microdeletion at 15q11.2 confirms a significant role for the SNORD116 C/D box snoRNA cluster in Prader–Willi syndrome

(2010) Angela L Duker et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing

(2010) Shivendra Kishore et al.   HUMAN MOLECULAR GENETICS

Development of the eating behaviour in Prader–Willi Syndrome: advances in our understanding

(2010) C J McAllister et al.   INTERNATIONAL JOURNAL OF OBESITY

Induced Pluripotent Stem Cells Can Be Used to Model the Genomic Imprinting Disorder Prader-Willi Syndrome

(2010) Jiayin Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serotonin 2C Receptor (5-HT2CR) mRNA Editing–Induced Down-Regulation of 5-HT2CR Function in Xenopus Oocytes: the Significance of Site C Editing

(2010) Michihisa Tohda et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

High-Throughput Multiplexed Transcript Analysis Yields Enhanced Resolution of 5-Hydroxytryptamine2C Receptor mRNA Editing Profiles

(2010) M. V. Morabito et al.   MOLECULAR PHARMACOLOGY

Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader–Willi syndrome

(2010) Michael V. Morabito et al.   NEUROBIOLOGY OF DISEASE

Neonatal Maternal Deprivation Response and Developmental Changes in Gene Expression Revealed by Hypothalamic Gene Expression Profiling in Mice

(2010) Feng Ding et al.   PLoS One

Digital Genome-Wide ncRNA Expression, Including SnoRNAs, across 11 Human Tissues Using PolyA-Neutral Amplification

(2010) John C. Castle et al.   PLoS One

Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes

(2010) Stormy J. Chamberlain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spliceosomal snRNA modifications and their function

(2010) John Karijolich et al.   RNA Biology

Identification of novel ribonucleo-protein complexes from the brain-specific snoRNA MBII-52

(2010) Y. Soeno et al.   RNA

Regionally reduced brain volume, altered serotonin neurochemistry, and abnormal behavior in mice null for the circadian rhythm output geneMagel2

(2009) Rebecca E. Mercer et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism

(2009) Jin Nakatani et al.   CELL

Expression of SNURF–SNRPN upstream transcripts and epigenetic regulatory genes during human spermatogenesis

(2009) Michaela Wawrzik et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour

(2009) Christine M. Doe et al.   HUMAN MOLECULAR GENETICS

Imprinting regulates mammalian snoRNA-encoding chromatin decondensation and neuronal nucleolar size

(2009) Karen N. Leung et al.   HUMAN MOLECULAR GENETICS

A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism

(2009) A. J. de Smith et al.   HUMAN MOLECULAR GENETICS

Long nuclear-retained non-coding RNAs and allele-specific higher-order chromatin organization at imprinted snoRNA gene arrays

(2009) P. Vitali et al.   JOURNAL OF CELL SCIENCE

Prader–Willi syndrome, Snord115, and Htr2c editing

(2009) Heather Glatt-Deeley et al.   NEUROGENETICS

Non-coding RNAs in imprinted gene clusters

(2008) Hélène Royo et al.   BIOLOGY OF THE CELL

A paternal deletion of MKRN3, MAGEL2 and NDN does not result in Prader–Willi syndrome

(2008) Deniz Kanber et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Gender influences monoallelic expression of ATP10A in human brain

(2008) Amber Hogart et al.   HUMAN GENETICS

Molecular Evolution of the HBII-52 snoRNA Cluster

(2008) Satu Nahkuri et al.   JOURNAL OF MOLECULAR BIOLOGY

Dysregulated Editing of Serotonin 2C Receptor mRNAs Results in Energy Dissipation and Loss of Fat Mass

(2008) Y. Kawahara et al.   JOURNAL OF NEUROSCIENCE

Necdin Plays a Role in the Serotonergic Modulation of the Mouse Respiratory Network: Implication for Prader-Willi Syndrome

(2008) S. Zanella et al.   JOURNAL OF NEUROSCIENCE

Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster

(2008) Trilochan Sahoo et al.   NATURE GENETICS

SnoRNA Snord116 (Pwcr1/MBII-85) Deletion Causes Growth Deficiency and Hyperphagia in Mice

(2008) Feng Ding et al.   PLoS One

snoTARGET shows that human orphan snoRNA targets locate close to alternative splice junctions

(2007) Peter S. Bazeley et al.   GENE