Small regulatory RNAs controlled by genomic imprinting and their contribution to human disease

Microprocessor dynamics and interactions at endogenous imprinted C19MC microRNA genes

(2012) C. Bellemer et al.   JOURNAL OF CELL SCIENCE

The dark side of a success story: microRNAs of the C19MC cluster in human tumours

(2012) Inga Flor et al.   JOURNAL OF PATHOLOGY

Specific small nucleolar RNA expression profiles in acute leukemia

(2012) W Valleron et al.   LEUKEMIA

The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r

(2012) Andrew Keniry et al.   NATURE CELL BIOLOGY

Induction of hepatocellular carcinoma by in vivo gene targeting

(2012) P.-R. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Imprinting: A Mammalian Epigenetic Discovery Model

(2011) Denise P. Barlow   Annual Review of Genetics

Do repeated arrays of regulatory small-RNA genes elicit genomic imprinting?

(2011) Stéphane Labialle et al.   BIOESSAYS

Recent acquisition of imprinting at the rodent Sfmbt2 locus correlates with insertion of a large block of miRNAs

(2011) Qianwei Wang et al.   BMC GENOMICS

Retrotransposition and genomic imprinting

(2011) M. Cowley et al.   Briefings in Functional Genomics

Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci

(2011) Sima J. Zacharek et al.   Cell Stem Cell

Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs

(2011) Norikatsu Miyoshi et al.   Cell Stem Cell

Deletion of the paternal allele of the imprinted MEST/PEG1 region in a patient with Silver-Russell syndrome features

(2011) T Eggermann et al.   CLINICAL GENETICS

MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer

(2011) K. J. Png et al.   GENES & DEVELOPMENT

MicroRNA miR-335 is crucial for the BRCA1 regulatory cascade in breast cancer development

(2011) Holger Heyn et al.   INTERNATIONAL JOURNAL OF CANCER

DLK1-DIO3 Genomic Imprinted MicroRNA Cluster at 14q32.2 Defines a Stemlike Subtype of Hepatocellular Carcinoma Associated with Poor Survival

(2011) John M. Luk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Placental-specific microRNA in maternal circulation – identification of appropriate pregnancy-associated microRNAs with diagnostic potential

(2011) Katerina Kotlabova et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Micro-RNA expression in cisplatin resistant germ cell tumor cell lines

(2011) Matthias Port et al.   Molecular Cancer

MicroRNA function and neurotrophin BDNF

(2011) Tadahiro Numakawa et al.   NEUROCHEMISTRY INTERNATIONAL

MicroRNA-296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3' untranslated region

(2011) A.-r. Yoon et al.   NUCLEIC ACIDS RESEARCH

MicroRNA regulation of homeostatic synaptic plasticity

(2011) J. E. Cohen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs 296 and 298 are imprinted and part of the GNAS/Gnas cluster and miR-296 targets IKBKE and Tmed9

(2011) J. E. Robson et al.   RNA

Role for piRNAs and Noncoding RNA in de Novo DNA Methylation of the Imprinted Mouse Rasgrf1 Locus

(2011) T. Watanabe et al.   SCIENCE

Imprinting on chromosome 20: Tissue-specific imprinting and imprinting mutations in the GNAS locus

(2010) Gavin Kelsey   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

MicroRNA profiling of adrenocortical tumors reveals miR-483 as a marker of malignancy

(2010) Erin E. Patterson et al.   CANCER

Oncogenic Role of miR-483-3p at the IGF2/483 Locus

(2010) A. Veronese et al.   CANCER RESEARCH

Epigenetic control of the expression of a primate-specific microRNA cluster in human cancer cells

(2010) Kuo-Wang Tsai et al.   Epigenetics

Paternally inherited microdeletion at 15q11.2 confirms a significant role for the SNORD116 C/D box snoRNA cluster in Prader–Willi syndrome

(2010) Angela L Duker et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The primate-specific microRNA gene cluster (C19MC) is imprinted in the placenta

(2010) M. Noguer-Dance et al.   HUMAN MOLECULAR GENETICS

Activation of the ImprintedDlk1-Dio3Region Correlates with Pluripotency Levels of Mouse Stem Cells

(2010) Lei Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type II Collagen Expression Is Regulated by Tissue-specific miR-675 in Human Articular Chondrocytes

(2010) Katarzyna A. Dudek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors

(2010) Xi Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

(2010) Matthias Stadtfeld et al.   NATURE

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

(2010) Alexander Swarbrick et al.   NATURE MEDICINE

Regulation of Hypoxia Inducible Factors (HIF) in Hypoxia and Normoxia During Placental Development

(2010) J. Patel et al.   PLACENTA

The Two Stem Cell MicroRNA Gene Clusters C19MC and miR-371-3 Are Activated by Specific Chromosomal Rearrangements in a Subgroup of Thyroid Adenomas

(2010) Volkhard Rippe et al.   PLoS One

Genetic and epigenetic dysregulation of imprinted genes in the brain

(2010) Kristin D Kernohan et al.   Epigenomics

Frequent Amplification of a chr19q13.41 MicroRNA Polycistron in Aggressive Primitive Neuroectodermal Brain Tumors

(2009) Meihua Li et al.   CANCER CELL

Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer

(2009) Wing Pui Tsang et al.   CARCINOGENESIS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Mef2-mediated transcription of the miR379–410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels

(2009) Roberto Fiore et al.   EMBO JOURNAL

A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism

(2009) A. J. de Smith et al.   HUMAN MOLECULAR GENETICS

C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts

(2009) M.-L. Bortolin-Cavaille et al.   NUCLEIC ACIDS RESEARCH

Human imprinting syndromes

(2009) Derek HK Lim et al.   Epigenomics

miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells

(2008) Thomas Würdinger et al.   CANCER CELL

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

MicroRNA-298 and MicroRNA-328 Regulate Expression of Mouse β-Amyloid Precursor Protein-converting Enzyme 1

(2008) Vincent Boissonneault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

(2008) Yvonne Tay et al.   NATURE

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

(2008) Qihong Huang et al.   NATURE CELL BIOLOGY

Prader-Willi phenotype caused by paternal deficiency for the HBII-85 C/D box small nucleolar RNA cluster

(2008) Trilochan Sahoo et al.   NATURE GENETICS

Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta

(2008) Yoichi Sekita et al.   NATURE GENETICS

Deletions and epimutations affecting the human 14q32.2 imprinted region in individuals with paternal and maternal upd(14)-like phenotypes

(2008) Masayo Kagami et al.   NATURE GENETICS

Conservation of the H19 noncoding RNA and H19-IGF2 imprinting mechanism in therians

(2008) Guillaume Smits et al.   NATURE GENETICS

Distinctive Patterns of MicroRNA Expression Associated with Karyotype in Acute Myeloid Leukaemia

(2008) Amanda Dixon-McIver et al.   PLoS One

Genomic imprinting at the mammalian Dlk1-Dio3 domain

(2008) Simao Teixeira da Rocha et al.   TRENDS IN GENETICS