Mycolactone displays anti-inflammatory effects on the nervous system

Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer

(2017) Junichiro En et al.   PLoS Neglected Tropical Diseases

Mechanistic insights into the inhibition of Sec61-dependent co- and post-translational translocation by mycolactone

(2016) Michael McKenna et al.   JOURNAL OF CELL SCIENCE

Mycolactone subverts immunity by selectively blocking the Sec61 translocon

(2016) Ludivine Baron et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mycolactone-mediated neurite degeneration and functional effects in cultured human and rat DRG neurons

(2016) U Anand et al.   Molecular Pain

Early alterations of Hedgehog signaling pathway in vascular endothelial cells after peripheral nerve injury elicit blood-nerve barrier disruption, nerve inflammation, and neuropathic pain development

(2016) Nathan Moreau et al.   PAIN

Pain regulation by non-neuronal cells and inflammation

(2016) R.-R. Ji et al.   SCIENCE

Crosstalk between the nociceptive and immune systems in host defence and disease

(2015) Stephen B. McMahon et al.   NATURE REVIEWS NEUROSCIENCE

Shaping mycolactone for therapeutic use against inflammatory disorders

(2015) Laure Guenin-Macé et al.   Science Translational Medicine

Microglia in the spinal cord and neuropathic pain

(2015) Makoto Tsuda   Journal of Diabetes Investigation

Pleiotropic molecular effects of theMycobacterium ulceransvirulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer

(2014) Belinda Hall et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mycobacterial Toxin Induces Analgesia in Buruli Ulcer by Targeting the Angiotensin Pathways

(2014) Estelle Marion et al.   CELL

The Angiotensin II Type 2 Receptor for Pain Control

(2014) A.H. Jan Danser et al.   CELL

Primary sensory neurons regulate Toll-like receptor-4-dependent activity of glial cells in dorsal root ganglia

(2014) K.-H. Tse et al.   NEUROSCIENCE

The Pathogenic Mechanism of the Mycobacterium ulcerans Virulence Factor, Mycolactone, Depends on Blockade of Protein Translocation into the ER

(2014) Belinda S. Hall et al.   PLoS Pathogens

Neuroinflammation and the generation of neuropathic pain

(2013) A Ellis et al.   BRITISH JOURNAL OF ANAESTHESIA

An update on Schwann cell biology — Immunomodulation, neural regulation and other surprises

(2013) Patricia J. Armati et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The neuroinflammatory role of Schwann cells in disease

(2013) Elke Ydens et al.   NEUROBIOLOGY OF DISEASE

Apoptosis in Buruli ulcer: a clinicopathological study of 45 cases

(2012) Elisa Zavattaro et al.   HISTOPATHOLOGY

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Immune responses of microglia in the spinal cord: Contribution to pain states

(2011) Dominic Schomberg et al.   EXPERIMENTAL NEUROLOGY

CCL2 Released from Neuronal Synaptic Vesicles in the Spinal Cord Is a Major Mediator of Local Inflammation and Pain after Peripheral Nerve Injury

(2011) J. Van Steenwinckel et al.   JOURNAL OF NEUROSCIENCE

Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression

(2011) L. Guenin-Mace et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly sensitive, operationally simple, cost/time effective detection of the mycolactones from the human pathogen Mycobacterium ulcerans

(2010) Thomas Spangenberg et al.   CHEMICAL COMMUNICATIONS

Mycolactone Suppresses T Cell Responsiveness by Altering Both Early Signaling and Posttranslational Events

(2009) S. Boulkroun et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide-induced inflammatory cytokine production by Schwann's cells dependent upon TLR4 expression

(2009) Hsiao-Nan Hao et al.   JOURNAL OF NEUROIMMUNOLOGY

Peroxisome proliferator-activated receptor-γ agonists suppress iNOS expression induced by LPS in rat primary Schwann cells

(2009) Fupeng Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Central Sensitization: A Generator of Pain Hypersensitivity by Central Neural Plasticity

(2009) Alban Latremoliere et al.   JOURNAL OF PAIN

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

(2009) Caroline Demangel et al.   NATURE REVIEWS MICROBIOLOGY

Mycolactone Is Responsible for the Painlessness of Mycobacterium ulcerans Infection (Buruli Ulcer) in a Murine Study

(2008) J. En et al.   INFECTION AND IMMUNITY