A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH

Use of ChAd3-EBO-Z Ebola virus vaccine in Malian and US adults, and boosting of Malian adults with MVA-BN-Filo: a phase 1, single-blind, randomised trial, a phase 1b, open-label and double-blind, dose-escalation trial, and a nested, randomised, double-blind, placebo-controlled trial

(2016) Milagritos D Tapia et al.   LANCET INFECTIOUS DISEASES

Safety and immunogenicity of a chimpanzee adenovirus-vectored Ebola vaccine in healthy adults: a randomised, double-blind, placebo-controlled, dose-finding, phase 1/2a study

(2016) Olga De Santis et al.   LANCET INFECTIOUS DISEASES

Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys

(2016) Erica N. Borducchi et al.   NATURE

Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events

(2016) Olga Sobolev et al.   NATURE IMMUNOLOGY

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

(2016) Katie Ewer et al.   NEW ENGLAND JOURNAL OF MEDICINE

The immunology of post-kala-azar dermal leishmaniasis (PKDL)

(2016) Eduard E. Zijlstra   Parasites & Vectors

TB vaccine development and the End TB Strategy: importance and current status

(2016) Helen A. Fletcher et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Combined Immune Therapy for the Treatment of Visceral Leishmaniasis

(2016) Rebecca J. Faleiro et al.   PLoS Neglected Tropical Diseases

Chimpanzee Adenovirus Vaccine Provides Multispecies Protection against Rift Valley Fever

(2016) George M. Warimwe et al.   Scientific Reports

Decreased Frequency and Secretion of CD26 Promotes Disease Progression in Indian Post Kala-azar Dermal Leishmaniasis

(2015) Shibabrata Mukherjee et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling

(2015) Kylie M. Quinn et al.   JOURNAL OF CLINICAL INVESTIGATION

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Pathogen-Specific T Cell Polyfunctionality Is a Correlate of T Cell Efficacy and Immune Protection

(2015) Anders Boyd et al.   PLoS One

CD8+ T cells in cutaneous leishmaniasis: the good, the bad, and the ugly

(2015) Fernanda O. Novais et al.   Seminars in Immunopathology

Development of Leishmania vaccines in the era of visceral leishmaniasis elimination

(2015) C. R. Engwerda et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Safety and immunogenicity of novel respiratory syncytial virus (RSV) vaccines based on the RSV viral proteins F, N and M2-1 encoded by simian adenovirus (PanAd3-RSV) and MVA (MVA-RSV); protocol for an open-label, dose-escalation, single-centre, phase 1 clinical trial in healthy adults

(2015) C A Green et al.   BMJ Open

Protective and Pathological Functions of CD8+T Cells in Leishmania braziliensis Infection

(2014) Thiago Marconi Cardoso et al.   INFECTION AND IMMUNITY

Modular Multiantigen T Cell Epitope-Enriched DNA Vaccine Against Human Leishmaniasis

(2014) S. Das et al.   Science Translational Medicine

Clinical and Parasitological Protection in a Leishmania infantum-Macaque Model Vaccinated with Adenovirus and the Recombinant A2 Antigen

(2014) Gabriel Grimaldi et al.   PLoS Neglected Tropical Diseases

CD8 T Cell Exhaustion in Human Visceral Leishmaniasis

(2013) Shalini Gautam et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

(2013) Richard D Antrobus et al.   MOLECULAR THERAPY

Molecular signatures of antibody responses derived from a systems biology study of five human vaccines

(2013) Shuzhao Li et al.   NATURE IMMUNOLOGY

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Report of the Post Kala-Azar Dermal Leishmaniasis (PKDL) consortium meeting, New Delhi, India, 27–29 June 2012

(2013) Philippe Desjeux et al.   Parasites & Vectors

Case study for a vaccine against leishmaniasis

(2013) Jorge Alvar et al.   VACCINE

The Economic Value of a Visceral Leishmaniasis Vaccine in Bihar State, India

(2012) Bruce Y. Lee et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Identifying gnostic predictors of the vaccine response

(2012) W Nicholas Haining et al.   CURRENT OPINION IN IMMUNOLOGY

Therapeutic Vaccination With Recombinant Adenovirus Reduces Splenic Parasite Burden in Experimental Visceral Leishmaniasis

(2012) A. Maroof et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Assessment of a Recombinant Simian Adenovirus ChAd63: A Potent New Vaccine Vector

(2012) Geraldine A. O’Hara et al.   JOURNAL OF INFECTIOUS DISEASES

Phase Ia Clinical Evaluation of the Safety and Immunogenicity of the Plasmodium falciparum Blood-Stage Antigen AMA1 in ChAd63 and MVA Vaccine Vectors

(2012) Susanne H. Sheehy et al.   PLoS One

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Merck Ad5/HIV induces broad innate immune activation that predicts CD8+ T-cell responses but is attenuated by preexisting Ad5 immunity

(2012) D. E. Zak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Adenovirus-Based Vaccines Induce Broad and Sustained T Cell Responses to HCV in Man

(2012) E. Barnes et al.   Science Translational Medicine

Comparing the safety and immunogenicity of a candidate TB vaccine MVA85A administered by intramuscular and intradermal delivery

(2012) Joel Meyer et al.   VACCINE

CD8+ T Cells in Leishmania Infections: Friends or Foes?

(2012) Simona Stäger et al.   Frontiers in Immunology

Visceral leishmaniasis: immunology and prospects for a vaccine

(2011) P.M. Kaye et al.   CLINICAL MICROBIOLOGY AND INFECTION

Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1

(2011) Paul F. Robbins et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors

(2011) Susanne H Sheehy et al.   MOLECULAR THERAPY

Leishmaniasis: complexity at the host–pathogen interface

(2011) Paul Kaye et al.   NATURE REVIEWS MICROBIOLOGY

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine for use in the prevention of visceral leishmaniasis

(2011) Jaya Chakravarty et al.   VACCINE

The development and clinical evaluation of second-generation leishmaniasis vaccines

(2011) Malcolm S. Duthie et al.   VACCINE

Systems vaccinology

(2011) Helder I. Nakaya et al.   Current Opinion in HIV and AIDS

Vaccines for the Leishmaniases: Proposals for a Research Agenda

(2011) et al.   PLoS Neglected Tropical Diseases

Immunomodulators: use in combined therapy against leishmaniasis

(2010) Jane E Dalton et al.   Expert Review of Anti-Infective Therapy

Immune evasive mechanisms contributing to persistent Leishmania donovani infection

(2010) Simona Stäger et al.   IMMUNOLOGIC RESEARCH

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with meglumine antimoniate for the treatment of cutaneous leishmaniasis

(2010) Evaldo Nascimento et al.   VACCINE

A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine when used in combination with sodium stibogluconate for the treatment of mucosal leishmaniasis

(2010) Alejandro Llanos-Cuentas et al.   VACCINE

Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques

(2010) Viraj Kulkarni et al.   VACCINE

A Multicistronic DNA Vaccine Induces Significant Protection against Tuberculosis in Mice and Offers Flexibility in the Expressed Antigen Repertoire

(2009) F.-A. Mir et al.   Clinical and Vaccine Immunology

Enhanced Lesional Foxp3 Expression and Peripheral Anergic Lymphocytes Indicate a Role for Regulatory T Cells in Indian Post-Kala-Azar Dermal Leishmaniasis

(2009) Sudipto Ganguly et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Immunological stimulation for the treatment of leishmaniasis: a modality worthy of serious consideration

(2009) Ahmed Mudawi Musa et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Efficacy of killed whole-parasite vaccines in the prevention of leishmaniasis—A meta-analysis

(2009) Sassan Noazin et al.   VACCINE

B7-H1 Blockade Increases Survival of Dysfunctional CD8+ T Cells and Confers Protection against Leishmania donovani Infections

(2009) Trupti Joshi et al.   PLoS Pathogens

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans

(2008) Troy D Querec et al.   NATURE IMMUNOLOGY

Immunochemotherapy of persistent post-kala-azar dermal leishmaniasis: a novel approach to treatment

(2007) Ahmed Mudawi Musa et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE