Phase Ia Clinical Evaluation of the Safety and Immunogenicity of the Plasmodium falciparum Blood-Stage Antigen AMA1 in ChAd63 and MVA Vaccine Vectors

Vaccination with Live Plasmodium yoelii Blood Stage Parasites under Chloroquine Cover Induces Cross-Stage Immunity against Malaria Liver Stage

(2014) E. Belnoue et al.   JOURNAL OF IMMUNOLOGY

SPICE: Exploration and analysis of post-cytometric complex multivariate datasets

(2011) Mario Roederer et al.   CYTOMETRY PART A

Blood stage vaccines forPlasmodium falciparum

(2011) Ruth D. Ellis et al.   Human vaccines & immunotherapeutics

The Requirement for Potent Adjuvants To Enhance the Immunogenicity and Protective Efficacy of Protein Vaccines Can Be Overcome by Prior Immunization with a Recombinant Adenovirus

(2011) S. C. de Cassan et al.   JOURNAL OF IMMUNOLOGY

Defying malaria: Arming T cells to halt malaria

(2011) Michael F Good et al.   NATURE MEDICINE

Protection against Malaria by MSP3 Candidate Vaccine

(2011) Sodiomon B. Sirima et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Field Trial to Assess a Blood-Stage Malaria Vaccine

(2011) Mahamadou A. Thera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transgene Optimization, Immunogenicity and In Vitro Efficacy of Viral Vectored Vaccines Expressing Two Alleles of Plasmodium falciparum AMA1

(2011) Sumi Biswas et al.   PLoS One

Virosome-Formulated Plasmodium falciparum AMA-1 & CSP Derived Peptides as Malaria Vaccine: Randomized Phase 1b Trial in Semi-Immune Adults & Children

(2011) Patrick Georges Cech et al.   PLoS One

Impact on Malaria Parasite Multiplication Rates in Infected Volunteers of the Protein-in-Adjuvant Vaccine AMA1-C1/Alhydrogel+CPG 7909

(2011) Christopher J. A. Duncan et al.   PLoS One

Adenovirus 5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part A: Safety and Immunogenicity in Seronegative Adults

(2011) Martha Sedegah et al.   PLoS One

Adenovirus-5-Vectored P. falciparum Vaccine Expressing CSP and AMA1. Part B: Safety, Immunogenicity and Protective Efficacy of the CSP Component

(2011) Cindy Tamminga et al.   PLoS One

A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects☆☆☆

(2011) Michael C. Keefer et al.   VACCINE

Blood-stage malaria vaccines — recent progress and future challenges

(2010) A. L. Goodman et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

Prime-boost vectored malaria vaccines: Progress and prospects

(2010) Adrian V. S. Hill et al.   Human vaccines & immunotherapeutics

New Candidate Vaccines against Blood-Stage Plasmodium falciparum Malaria: Prime-Boost Immunization Regimens Incorporating Human and Simian Adenoviral Vectors and Poxviral Vectors Expressing an Optimized Antigen Based on Merozoite Surface Protein 1

(2010) A. L. Goodman et al.   INFECTION AND IMMUNITY

Enhancing Blood-Stage Malaria Subunit Vaccine Immunogenicity in Rhesus Macaques by Combining Adenovirus, Poxvirus, and Protein-in-Adjuvant Vaccines

(2010) S. J. Draper et al.   JOURNAL OF IMMUNOLOGY

Malaria elimination: worthy, challenging, and just possible

(2010) Pam Das et al.   LANCET

Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein

(2010) Martha Sedegah et al.   MALARIA JOURNAL

Clinical Protection from Falciparum Malaria Correlates with Neutrophil Respiratory Bursts Induced by Merozoites Opsonized with Human Serum Antibodies

(2010) Charlotte Joos et al.   PLoS One

Comparison of T cell immune responses induced by vectored HIV vaccines in non-human primates and humans

(2010) Andrew J. Bett et al.   VACCINE

Adenovectors induce functional antibodies capable of potent inhibition of blood stage malaria parasite growth

(2010) Joseph T. Bruder et al.   VACCINE

Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults

(2010) Mark A. Pierce et al.   VACCINE

Tailoring subunit vaccine immunogenicity: Maximizing antibody and T cell responses by using combinations of adenovirus, poxvirus and protein-adjuvant vaccines against Plasmodium falciparum MSP1

(2010) Alexander D. Douglas et al.   VACCINE

Novel adenovirus vector-based vaccines for HIV-1

(2010) Dan H Barouch   Current Opinion in HIV and AIDS

Recombinant Viral Vaccines Expressing Merozoite Surface Protein-1 Induce Antibody- and T Cell-Mediated Multistage Protection against Malaria

(2009) Simon J. Draper et al.   Cell Host & Microbe

Anti-Apical-Membrane-Antigen-1 Antibody Is More Effective than Anti-42-Kilodalton-Merozoite-Surface-Protein-1 Antibody in Inhibiting Plasmodium falciparum Growth, as Determined by the In Vitro Growth Inhibition Assay

(2009) K. Miura et al.   Clinical and Vaccine Immunology

Viruses as vaccine vectors for infectious diseases and cancer

(2009) Simon J. Draper et al.   NATURE REVIEWS MICROBIOLOGY

Phase 1/2a Study of the Malaria Vaccine Candidate Apical Membrane Antigen-1 (AMA-1) Administered in Adjuvant System AS01B or AS02A

(2009) Michele D. Spring et al.   PLoS One

Humoral Immune Response to Mixed PfAMA1 Alleles; Multivalent PfAMA1 Vaccines Induce Broad Specificity

(2009) Kwadwo A. Kusi et al.   PLoS One

Extreme Polymorphism in a Vaccine Antigen and Risk of Clinical Malaria: Implications for Vaccine Development

(2009) S. L. Takala et al.   Science Translational Medicine

A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel® with CPG 7909, using two different formulations and dosing intervals

(2009) Ruth D. Ellis et al.   VACCINE

Cell-mediated immunity elicited by the blood stage malaria vaccine apical membrane antigen 1 in Malian adults: Results of a Phase I randomized trial

(2009) Kirsten E. Lyke et al.   VACCINE

Prevalence of serum neutralizing antibodies against chimpanzee adenovirus 63 and human adenovirus 5 in Kenyan Children, in the context of vaccine vector efficacy

(2009) M. Dudareva et al.   VACCINE

Immunity to malaria: more questions than answers

(2008) Jean Langhorne et al.   NATURE IMMUNOLOGY

Effective induction of high-titer antibodies by viral vector vaccines

(2008) Simon J Draper et al.   NATURE MEDICINE

Phase 1 Trial of AMA1-C1/Alhydrogel plus CPG 7909: An Asexual Blood-Stage Vaccine for Plasmodium falciparum Malaria

(2008) Gregory E. D. Mullen et al.   PLoS One

Apical membrane antigen 1: a malaria vaccine candidate in review

(2008) Edmond J. Remarque et al.   TRENDS IN PARASITOLOGY

Development and characterization of a standardized ELISA including a reference serum on each plate to detect antibodies induced by experimental malaria vaccines

(2007) Kazutoyo Miura et al.   VACCINE