Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy

Antagonistic pleiotropy and mutation accumulation influence human senescence and disease

(2017) Juan Antonio Rodríguez et al.   Nature Ecology & Evolution

Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility

(2016) Hamdi Mbarek et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic prediction of coronary heart disease

(2016) Gad Abraham et al.   EUROPEAN HEART JOURNAL

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Ultrastructural study of spermatogenesis in KSR2 deficient mice

(2015) Elena Moretti et al.   TRANSGENIC RESEARCH

Pre-eclampsia has an adverse impact on maternal and fetal health

(2015) Saunders Lin et al.   Translational Research

Polycystic ovarian syndrome is accompanied by repression of gene signatures associated with biosynthesis and metabolism of steroids, cholesterol and lipids

(2015) Dessie Salilew-Wondim et al.   Journal of Ovarian Research

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Genome-Wide Association Study of Parity in Bangladeshi Women

(2015) Briseis Aschebrook-Kilfoy et al.   PLoS One

Fast Principal Component Analysis of Large-Scale Genome-Wide Data

(2014) Gad Abraham et al.   PLoS One

A Twin Study of Breastfeeding With a Preliminary Genome-Wide Association Scan

(2014) Lucia Colodro-Conde et al.   Twin Research and Human Genetics

A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness

(2014) Jared O'Connell et al.   PLoS Genetics

Lipid concentrations and semen quality: the LIFE study

(2014) E. F. Schisterman et al.   Andrology

Gene expression in subcutaneous adipose tissue differs in women with polycystic ovary syndrome and controls matched pair-wise for age, body weight, and body mass index

(2014) Louise Mannerås-Holm et al.   Adipocyte

Common Risk Alleles for Inflammatory Diseases Are Targets of Recent Positive Selection

(2013) Towfique Raj et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Selection and Adaptation in the Human Genome

(2013) Wenqing Fu et al.   Annual Review of Genomics and Human Genetics

Identifying Recent Adaptations in Large-Scale Genomic Data

(2013) Sharon R. Grossman et al.   CELL

Heart Disease and Stroke Statistics—2014 Update

(2013) Alan S. Go et al.   CIRCULATION

Gene expression drives local adaptation in humans

(2013) H. B. Fraser   GENOME RESEARCH

Genome-wide association studies and epistasis analyses of candidate genes related to age at menarche and age at natural menopause in a Korean population

(2013) Jung-A. Pyun et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Recent human adaptation: genomic approaches, interpretation and insights

(2013) Laura B. Scheinfeldt et al.   NATURE REVIEWS GENETICS

Genetic Variation and Reproductive Timing: African American Women from the Population Architecture Using Genomics and Epidemiology (PAGE) Study

(2013) Kylee L. Spencer et al.   PLoS One

Cardiovascular disease risk in women with PCOS

(2013) Anuja Dokras   STEROIDS

Population genomics of rapid adaptation by soft selective sweeps

(2013) Philipp W. Messer et al.   TRENDS IN ECOLOGY & EVOLUTION

Genome-wide Association Study Identifies Candidate Genes for Male Fertility Traits in Humans

(2012) Gülüm Kosova et al.   AMERICAN JOURNAL OF HUMAN GENETICS

rehh: an R package to detect footprints of selection in genome-wide SNP data from haplotype structure

(2012) Mathieu Gautier et al.   BIOINFORMATICS

Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22a21)

(2012) Ikumi Tamai   BIOPHARMACEUTICS & DRUG DISPOSITION

Coronary Heart Disease in Young Adults

(2012) Jessica B. Rubin et al.   Current Atherosclerosis Reports

Investigation of gene expression profiles before and after embryonic genome activation and assessment of functional pathways at the human metaphase II oocyte and blastocyst stage

(2012) Georgia Kakourou et al.   FERTILITY AND STERILITY

Expression of apoptosis-related genes in the endometrium of polycystic ovary syndrome patients during the window of implantation

(2012) Ling Yan et al.   GENE

Limited Evidence for Classic Selective Sweeps in African Populations

(2012) J. M. Granka et al.   GENETICS

COL4A1 and COL4A2 mutations and disease: insights into pathogenic mechanisms and potential therapeutic targets

(2012) D. S. Kuo et al.   HUMAN MOLECULAR GENETICS

MicroRNA expression patterns in the bovine mammary gland are affected by stage of lactation1

(2012) M. Wang et al.   JOURNAL OF DAIRY SCIENCE

Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolin-deficient mice

(2012) Curzio Solca et al.   JOURNAL OF LIPID RESEARCH

Cholesterol and male fertility: What about orphans and adopted?

(2012) Salwan Maqdasy et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Evidence of widespread selection on standing variation in Europe at height-associated SNPs

(2012) Michael C Turchin et al.   NATURE GENETICS

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Patterns of Ancestry, Signatures of Natural Selection, and Genetic Association with Stature in Western African Pygmies

(2012) Joseph P. Jarvis et al.   PLoS Genetics

Patterns of Cis Regulatory Variation in Diverse Human Populations

(2012) Barbara E. Stranger et al.   PLoS Genetics

Antagonistic pleiotropy as a widespread mechanism for the maintenance of polymorphic disease alleles

(2011) Ashley JR Carter et al.   BMC Medical Genetics

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

Ensembl 2012

(2011) P. Flicek et al.   NUCLEIC ACIDS RESEARCH

Classic Selective Sweeps Were Rare in Recent Human Evolution

(2011) R. D. Hernandez et al.   SCIENCE

Atherosclerosis in Ancient Egyptian Mummies

(2011) Adel H. Allam et al.   JACC-Cardiovascular Imaging

Genome-Wide Association Study SNPs in the Human Genome Diversity Project Populations: Does Selection Affect Unlinked SNPs with Shared Trait Associations?

(2011) Amanda M. Casto et al.   PLoS Genetics

The Genetics of Human Adaptation: Hard Sweeps, Soft Sweeps, and Polygenic Adaptation

(2010) Jonathan K. Pritchard et al.   CURRENT BIOLOGY

Polycystic ovary syndrome: an ancient disorder?

(2010) Ricardo Azziz et al.   FERTILITY AND STERILITY

Homeorhetic adaptation to lactation: comparative transcriptome analysis of mammary, liver, and adipose tissue during the transition from pregnancy to lactation in rats

(2010) Osman V. Patel et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging

(2010) I. Surakka et al.   GENOME RESEARCH

Genetic predictors of medically refractory ulcerative colitis

(2010) Talin Haritunians et al.   INFLAMMATORY BOWEL DISEASES

Adaptation – not by sweeps alone

(2010) Jonathan K. Pritchard et al.   NATURE REVIEWS GENETICS

Natural selection on EPAS1 (HIF2 ) associated with low hemoglobin concentration in Tibetan highlanders

(2010) C. M. Beall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constructing genomic maps of positive selection in humans: Where do we go from here?

(2009) J. M. Akey   GENOME RESEARCH

Identification of genetic markers for productive life in commercial sows1

(2009) B. E. Mote et al.   JOURNAL OF ANIMAL SCIENCE

Association analyses of candidate single nucleotide polymorphisms on reproductive traits in swine1,2

(2009) L. A. Rempel et al.   JOURNAL OF ANIMAL SCIENCE

Gene expression microarray profiles of cumulus cells in lean and overweight-obese polycystic ovary syndrome patients

(2009) S. Kenigsberg et al.   MOLECULAR HUMAN REPRODUCTION

Genome-wide scans for footprints of natural selection

(2009) T. K. Oleksyk et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Natural selection in a contemporary human population

(2009) S. G. Byars et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Maternal Low-Protein Diet or Hypercholesterolemia Reduces Circulating Essential Amino Acids and Leads to Intrauterine Growth Restriction

(2008) K. K. S. Bhasin et al.   DIABETES

Selective Sweep at a Quantitative Trait Locus in the Presence of Background Genetic Variation

(2008) Luis-Miguel Chevin et al.   GENETICS

Genome-wide nucleotide-level mammalian ancestor reconstruction

(2008) B. Paten et al.   GENOME RESEARCH

Gene Expression Levels Are a Target of Recent Natural Selection in the Human Genome

(2008) S. Kudaravalli et al.   MOLECULAR BIOLOGY AND EVOLUTION

Local injury to the endometrium in controlled ovarian hyperstimulation cycles improves implantation rates

(2007) Liang Zhou et al.   FERTILITY AND STERILITY