Pharmacological and pathophysiological roles of carnitine/organic cation transporters (OCTNs: SLC22A4, SLC22A5 and Slc22a21)

Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro

(2012) Manali Mukherjee et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Substrate Pharmacophore for the Human Organic Cation/Carnitine Transporter Identifies Compounds Associated with Rhabdomyolysis

(2012) Sean Ekins et al.   MOLECULAR PHARMACEUTICS

Carnitine Precursor γ-Butyrobetaine is a Novel Substrate of the Na+- and Cl−-dependent GABA Transporter Gat2

(2011) Takeo Nakanishi et al.   Drug Metabolism and Pharmacokinetics

Role of organic cation transporters in drug-induced toxicity

(2011) Giuliano Ciarimboli   Expert Opinion on Drug Metabolism & Toxicology

Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis

(2011) Chao Xuan et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Oxaliplatin Transport Mediated by Organic Cation/Carnitine Transporters OCTN1 and OCTN2 in Overexpressing Human Embryonic Kidney 293 Cells and Rat Dorsal Root Ganglion Neurons

(2011) N. N. Jong et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Functional Characterization of Apical Transporters Expressed in Rat Proximal Tubular Cells (PTCs) in Primary Culture

(2011) Takeo Nakanishi et al.   MOLECULAR PHARMACEUTICS

Synthesis, Transport and Mechanism of a Type I Prodrug:l-Carnitine Ester of Prednisolone

(2011) Jing-xin Mo et al.   MOLECULAR PHARMACEUTICS

Upregulation of mammary gland OCTNs maintains carnitine homeostasis in suckling infants

(2010) Anne-Marie Lamhonwah et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Organic Cation Transporter-Mediated Renal Secretion of Ipratropium and Tiotropium in Rats and Humans

(2010) T. Nakanishi et al.   DRUG METABOLISM AND DISPOSITION

Functional Expression of Carnitine/Organic Cation Transporter OCTN1/SLC22A4 in Mouse Small Intestine and Liver

(2010) T. Sugiura et al.   DRUG METABOLISM AND DISPOSITION

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gene Knockout and Metabolome Analysis of Carnitine/Organic Cation Transporter OCTN1

(2010) Yukio Kato et al.   PHARMACEUTICAL RESEARCH

Hepatic uptake of γ-butyrobetaine, a precursor of carnitine biosynthesis, in rats

(2009) Masaharu Fujita et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Interaction between pivaloylcarnitine and l-carnitine transport into L6 cells overexpressing hOCTN2

(2009) Liliane Todesco et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Carnitine/Organic Cation Transporter OCTN2 (Slc22a5) Is Responsible for Renal Secretion of Cephaloridine in Mice

(2009) T. Kano et al.   DRUG METABOLISM AND DISPOSITION

Transport of Ipratropium, an Anti-Chronic Obstructive Pulmonary Disease Drug, Is Mediated by Organic Cation/Carnitine Transporters in Human Bronchial Epithelial Cells: Implications for Carrier-Mediated Pulmonary Absorption

(2009) Toshimichi Nakamura et al.   MOLECULAR PHARMACEUTICS

Functional Characterization of Ergothioneine Transport by Rat Organic Cation/Carnitine Transporter Octn1 (slc22a4)

(2008) Toshimichi Nakamura et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Interaction of Imatinib with Human Organic Ion Carriers

(2008) S. Hu et al.   CLINICAL CANCER RESEARCH

The Carnitine Transporter SLC22A5 Is Not a General Drug Transporter, but It Efficiently Translocates Mildronate

(2008) S. Grigat et al.   DRUG METABOLISM AND DISPOSITION

PDZK1 Regulates Two Intestinal Solute Carriers (Slc15a1 and Slc22a5) in Mice

(2008) T. Sugiura et al.   DRUG METABOLISM AND DISPOSITION

Role of Na+/L-carnitine Transporter (OCTN2) in Renal Handling of Pivaloylcarnitine and Valproylcarnitine Formed during Pivalic Acid-containing Prodrugs and Valproic Acid Treatment

(2008) Shuichi Ohnishi et al.   Drug Metabolism and Pharmacokinetics

Functional relevance of carnitine transporter OCTN2 to brain distribution of l-carnitine and acetyl-l-carnitine across the blood-brain barrier

(2003) Yasuto Kido et al.   JOURNAL OF NEUROCHEMISTRY