Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study

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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

(2016) Johannes Kettunen et al.   Nature Communications

Metabolite Profiling and Cardiovascular Event Risk: A Prospective Study of 3 Population-Based Cohorts

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Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Cardiovascular Epidemiology and Genetics

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Albumin-deficient mouse models for studying metabolism of human albumin and pharmacokinetics of albumin-based drugs

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AMP-activated protein kinase suppresses the expression of LXR/SREBP-1 signaling-induced ANGPTL8 in HepG2 cells

(2015) Jinmi Lee et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

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(2015) Dmitry Shungin et al.   NATURE

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(2015) Yan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIF3A association with adiposity: the story begins before birth

(2015) Hong Pan et al.   Epigenomics

Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

(2015) Elisabeth M. van Leeuwen et al.   Nature Communications

Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

(2015) Anubha Mahajan et al.   PLoS Genetics

Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Cardiovascular Epidemiology and Genetics

(2015) Pasi Soininen et al.   Circulation-Cardiovascular Genetics

HIF3A DNA Methylation Is Associated with Childhood Obesity and ALT

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Rare-Variant Association Analysis: Study Designs and Statistical Tests

(2014) Seunggeung Lee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks

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Regulation of lipoprotein lipase by Angptl4

(2014) Wieneke Dijk et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Re-sequencing Expands Our Understanding of the Phenotypic Impact of Variants at GWAS Loci

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Biomarker Profiling by Nuclear Magnetic Resonance Spectroscopy for the Prediction of All-Cause Mortality: An Observational Study of 17,345 Persons

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High-Density Lipoprotein Particle Subclass Heterogeneity and Incident Coronary Heart Disease

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Lipoprotein subclass profiles in individuals with varying degrees of glucose tolerance: a population-based study of 9399 Finnish men

(2013) J. Wang et al.   JOURNAL OF INTERNAL MEDICINE

Serum albumin acts as a shuttle to enhance cholesterol efflux from cells

(2013) Sandhya Sankaranarayanan et al.   JOURNAL OF LIPID RESEARCH

Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease

(2013) Peter Würtz et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained

(2013) Ying Wu et al.   PLoS Genetics

The Impact of Partial and Complete Loss-of-Function Mutations in Endothelial Lipase on High-Density Lipoprotein Levels and Functionality in Humans

(2012) Roshni R. Singaraja et al.   Circulation-Cardiovascular Genetics

Finding genes and variants for lipid levels after genome-wide association analysis

(2012) Cristen J. Willer et al.   CURRENT OPINION IN LIPIDOLOGY

Liver phospholipid transfer protein (PLTP) expression with a PLTP-null background promotes very low-density lipoprotein production in mice

(2012) Amirfarbod Yazdanyar et al.   HEPATOLOGY

An integrated encyclopedia of DNA elements in the human genome

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Genome-wide association study identifies multiple loci influencing human serum metabolite levels

(2012) Johannes Kettunen et al.   NATURE GENETICS

Improved whole-chromosome phasing for disease and population genetic studies

(2012) Olivier Delaneau et al.   NATURE METHODS

Epistatic Selection between Coding and Regulatory Variation in Human Evolution and Disease

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Apolipoprotein A-V; a potent triglyceride reducer

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Hypoxia-inducible factor-1 (HIF-1) promotes LDL and VLDL uptake through inducing VLDLR under hypoxia

(2011) Guo-Min Shen et al.   BIOCHEMICAL JOURNAL

Genetic associations with lipoprotein subfractions provide information on their biological nature

(2011) Ann-Kristin Petersen et al.   HUMAN MOLECULAR GENETICS

Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability

(2011) Serena Sanna et al.   PLoS Genetics

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

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The NIH Roadmap Epigenomics Mapping Consortium

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Variance component model to account for sample structure in genome-wide association studies

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High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

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Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men

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The ARF-Like GTPase ARFRP1 Is Essential for Lipid Droplet Growth and Is Involved in the Regulation of Lipolysis

(2009) A. Hommel et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

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Glycerol-3-phosphate acyltransferases: Rate limiting enzymes of triacylglycerol biosynthesis

(2008) Angela A. Wendel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS