Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained

Genotype Imputation of MetabochipSNPs Using a Study-Specific Reference Panel of ∼4,000 Haplotypes in African Americans From the Women's Health Initiative

(2012) Eric Yi Liu et al.   GENETIC EPIDEMIOLOGY

Evaluation of the Metabochip Genotyping Array in African Americans and Implications for Fine Mapping of GWAS-Identified Loci: The PAGE Study

(2012) Steven Buyske et al.   PLoS One

Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project

(2012) Kiran Musunuru et al.   PLoS One

The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits

(2012) Benjamin F. Voight et al.   PLoS Genetics

The Next PAGE in Understanding Complex Traits: Design for the Analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study

(2011) Tara C. Matise et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Evidence of How rs7575840 Influences Apolipoprotein B–Containing Lipid Particles

(2011) Blake E. Haas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Functional importance of apolipoprotein A5 185G in the activation of lipoprotein lipase

(2011) Yi-Jan Huang et al.   CLINICA CHIMICA ACTA

Cellular characterisation of the GCKR P446L variant associated with type 2 diabetes risk

(2011) M. G. Rees et al.   DIABETOLOGIA

Haplotype variation and genotype imputation in African populations

(2011) Lucy Huang et al.   GENETIC EPIDEMIOLOGY

Variants in ZNF365 isoform D are associated with Crohn's disease

(2011) T. Haritunians et al.   GUT

Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association

(2011) Andrew R. Wood et al.   HUMAN MOLECULAR GENETICS

Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour

(2011) J. F. Peden et al.   HUMAN MOLECULAR GENETICS

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

(2011) Gosia Trynka et al.   NATURE GENETICS

Quantifying the Underestimation of Relative Risks from Genome-Wide Association Studies

(2011) Chris Spencer et al.   PLoS Genetics

Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol

(2011) Sumeet A. Khetarpal et al.   PLoS Genetics

Genetic Determinants of Lipid Traits in Diverse Populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study

(2011) Logan Dumitrescu et al.   PLoS Genetics

Fine Mapping of Five Loci Associated with Low-Density Lipoprotein Cholesterol Detects Variants That Double the Explained Heritability

(2011) Serena Sanna et al.   PLoS Genetics

Transferability of Type 2 Diabetes Implicated Loci in Multi-Ethnic Cohorts from Southeast Asia

(2011) Xueling Sim et al.   PLoS Genetics

LocusZoom: regional visualization of genome-wide association scan results

(2010) R. J. Pruim et al.   BIOINFORMATICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

A functional polymorphism in the HMGCR promoter affects transcriptional activity but not the risk for Alzheimer disease in Swedish populations

(2010) Lina Keller et al.   BRAIN RESEARCH

Patterns of linkage disequilibrium in different populations: implications and opportunities for lipid-associated loci identified from genome-wide association studies

(2010) Yik-Ying Teo et al.   CURRENT OPINION IN LIPIDOLOGY

Identifying candidate causal variants via trans-population fine-mapping

(2010) Yik-Ying Teo et al.   GENETIC EPIDEMIOLOGY

A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans

(2010) Víctor Acuña-Alonzo et al.   HUMAN MOLECULAR GENETICS

Cohort Profile: The Cebu Longitudinal Health and Nutrition Survey

(2010) L. S. Adair et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

(2010) Benjamin F Voight et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Genome-wide association studies in diverse populations

(2010) Noah A. Rosenberg et al.   NATURE REVIEWS GENETICS

Methodological challenges of genome-wide association analysis in Africa

(2010) Yik-Ying Teo et al.   NATURE REVIEWS GENETICS

Incidence of and risk factors for type-2 diabetes in a general population: The Tromsø Study

(2010) Josepha Joseph et al.   SCANDINAVIAN JOURNAL OF PUBLIC HEALTH

APOE Genotype, Lipids, and Coronary Heart Disease Risk

(2009) Heather Ward et al.   ARCHIVES OF INTERNAL MEDICINE

GWAF: an R package for genome-wide association analyses with family data

(2009) Ming-Huei Chen et al.   BIOINFORMATICS

Changes in Insulin Sensitivity and Insulin Release in Relation to Glycemia and Glucose Tolerance in 6,414 Finnish Men

(2009) A. Stancakova et al.   DIABETES

Degradation of LDLR protein mediated by ‘gain of function’ PCSK9 mutants in normal and ARH cells

(2008) Tommaso Fasano et al.   ATHEROSCLEROSIS

The functional interaction on in vitro gene expression of APOA5 SNPs, defining haplotype APOA5⁎2, and their paradoxical association with plasma triglyceride but not plasma apoAV levels

(2008) Jutta Palmen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Casting a wider net for diabetes susceptibility genes

(2008) Mark I McCarthy   NATURE GENETICS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

(2008) Yurii S Aulchenko et al.   NATURE GENETICS

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

(2008) Mark I. McCarthy et al.   NATURE REVIEWS GENETICS