Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults

Accelerometry and physical activity questionnaires - a systematic review

(2016) Stephanie Skender et al.   BMC PUBLIC HEALTH

Functional Analysis of a Carotid Intima-Media Thickness Locus ImplicatesBCAR1and Suggests a Causal VariantCLINICAL PERSPECTIVE

(2015) Freya Boardman-Pretty et al.   Circulation-Cardiovascular Genetics

Pappa2 deletion alters IGFBPs but has little effect on glucose disposal or adiposity

(2015) Julian K. Christians et al.   GROWTH HORMONE & IGF RESEARCH

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

(2015) Melina Claussnitzer et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

(2015) Thomas W. Winkler et al.   PLoS Genetics

Functional Analysis of a Carotid Intima-Media Thickness Locus ImplicatesBCAR1and Suggests a Causal VariantCLINICAL PERSPECTIVE

(2015) Freya Boardman-Pretty et al.   Circulation-Cardiovascular Genetics

EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data

(2014) Thomas W. Winkler et al.   BIOINFORMATICS

Synthesis of 53 tissue and cell line expression QTL datasets reveals master eQTLs

(2014) Xiaoling Zhang et al.   BMC GENOMICS

Epigenetic adaptation to regular exercise in humans

(2014) Charlotte Ling et al.   DRUG DISCOVERY TODAY

FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

(2014) Qibin Qi et al.   HUMAN MOLECULAR GENETICS

Quality control and conduct of genome-wide association meta-analyses

(2014) Thomas W Winkler et al.   Nature Protocols

Gene Expression Signatures of Coronary Heart Disease

(2013) Roby Joehanes et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Pregnancy Associated Plasma Protein A2 (PAPP-A2) Affects Bone Size and Shape and Contributes to Natural Variation in Postnatal Growth in Mice

(2013) Julian Kenneth Christians et al.   PLoS One

Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity

(2013) J. Y. Cha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene × Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry

(2013) Shafqat Ahmad et al.   PLoS Genetics

Detection of a novel frameshift mutation and regions with homozygosis within ARHGEF28 gene in familial amyotrophic lateral sclerosis

(2013) Cristian A. Droppelmann et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Co-aggregation of RNA binding proteins in ALS spinal motor neurons: evidence of a common pathogenic mechanism

(2012) Brian A. Keller et al.   ACTA NEUROPATHOLOGICA

Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

(2012) Romain Barrès et al.   Cell Metabolism

Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution But No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits

(2012) Kati Kristiansson et al.   Circulation-Cardiovascular Genetics

No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels

(2012) Robert A. Scott et al.   DIABETES

Genome wide analysis reveals association of a FTO gene variant with epigenetic changes

(2012) Markus Sällman Almén et al.   GENOMICS

A systematic review of reliability and objective criterion-related validity of physical activity questionnaires

(2012) Hendrik JF Helmerhorst et al.   International Journal of Behavioral Nutrition and Physical Activity

FTO genotype is associated with phenotypic variability of body mass index

(2012) Jian Yang et al.   NATURE

Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations

(2012) Yukinori Okada et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits

(2012) Benjamin F. Voight et al.   PLoS Genetics

Lifestyle Interaction With Fat Mass and Obesity-Associated (FTO) Genotype and Risk of Obesity in Apparently Healthy U.S. Women

(2011) T. Ahmad et al.   DIABETES CARE

Pregnancy-Associated Plasma Protein-A2 (PAPP-A2): Tissue Expression and Biological Consequences of Gene Knockout in Mice

(2011) Cheryl A. Conover et al.   ENDOCRINOLOGY

Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability

(2011) Zoltán Kutalik et al.   GENETIC EPIDEMIOLOGY

To stratify or not to stratify: power considerations for population-based genome-wide association studies of quantitative traits

(2011) Gundula Behrens et al.   GENETIC EPIDEMIOLOGY

Genome-Wide Meta-Analysis of Joint Tests for Genetic and Gene-Environment Interaction Effects

(2011) Hugues Aschard et al.   HUMAN HEREDITY

Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

(2011) Gidon Toperoff et al.   HUMAN MOLECULAR GENETICS

CEP70 Protein Interacts with γ-Tubulin to Localize at the Centrosome and Is Critical for Mitotic Spindle Assembly

(2011) Xingjuan Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A High Intake of Saturated Fatty Acids Strengthens the Association between the Fat Mass and Obesity-Associated Gene and BMI

(2011) Dolores Corella et al.   JOURNAL OF NUTRITION

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-Wide Association of BMI in African Americans

(2011) Maggie C.Y. Ng et al.   Obesity

Genome-Wide Association Study Identifies Novel Restless Legs Syndrome Susceptibility Loci on 2p14 and 16q12.1

(2011) Juliane Winkelmann et al.   PLoS Genetics

MAPK/ERK Signaling Regulates Insulin Sensitivity to Control Glucose Metabolism in Drosophila

(2011) Wei Zhang et al.   PLoS Genetics

Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children

(2011) Tuomas O. Kilpeläinen et al.   PLOS MEDICINE

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

The rs1800629 Polymorphism in the TNF Gene Interacts with Physical Activity on the Changes in C-reactive Protein Levels in the Finnish Diabetes Prevention Study

(2010) T. O. Kilpeläinen et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

(2010) Iris M Heid et al.   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Integrated Genetic and Epigenetic Analysis Identifies Haplotype-Specific Methylation in the FTO Type 2 Diabetes and Obesity Susceptibility Locus

(2010) Christopher G. Bell et al.   PLoS One

Physical activity attenuates the body mass index–increasing influence of genetic variation in the FTO gene

(2009) Karani S Vimaleswaran et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Fat and carbohydrate intake modify the association between genetic variation in the FTO genotype and obesity

(2009) Emily Sonestedt et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium

(2009) Nancy L. Heard-Costa et al.   PLoS Genetics

Practical Issues in Imputation-Based Association Mapping

(2008) Yongtao Guan et al.   PLoS Genetics