Sex Differences in the Cognitive and Hippocampal Effects of Streptozotocin in an Animal Model of Sporadic AD

Streptozotocin-Induced Sporadic Alzheimer's Disease: Selection of Appropriate Dose

(2018) Jogender Mehla et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-β and Tau Pathology of Alzheimer's Disease Induced by Diabetes in a Rabbit Animal Model

(2018) Claudine L. Bitel et al.   JOURNAL OF ALZHEIMERS DISEASE

Animal Models of the Sporadic Form of Alzheimer's Disease: Focus on the Disease and Not Just the Lesions1

(2018) Khalid Iqbal et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidative stress and pro-inflammatory cytokines may act as one of the signals for regulating microRNAs expression in Alzheimer’s disease

(2017) Kedar N. Prasad   MECHANISMS OF AGEING AND DEVELOPMENT

Potential benefits of phytochemicals against Alzheimer's disease

(2017) Emma L. Wightman   PROCEEDINGS OF THE NUTRITION SOCIETY

Cytosolic Abnormally Hyperphosphorylated Tau But Not Paired Helical Filaments Sequester Normal MAPs and Inhibit Microtubule Assembly

(2017) Khalid Iqbal et al.   JOURNAL OF ALZHEIMERS DISEASE

Why Women Have More Alzheimer's Disease Than Men: Gender and Mitochondrial Toxicity of Amyloid-β Peptide

(2017) Jose Viña et al.   JOURNAL OF ALZHEIMERS DISEASE

Cellular and molecular mechanisms of sexual differentiation in the mammalian nervous system

(2016) Nancy G. Forger et al.   FRONTIERS IN NEUROENDOCRINOLOGY

NSAIDs protect neurons and preserve memory in a mouse model of AD

(2016) Hemi Malkki   Nature Reviews Neurology

Asperterpenes A and B, two unprecedented meroterpenoids from Aspergillus terreus with BACE1 inhibitory activities

(2016) Changxing Qi et al.   Chemical Science

Quantitative Expression Analysis of APP Pathway and Tau Phosphorylation-Related Genes in the ICV STZ-Induced Non-Human Primate Model of Sporadic Alzheimer’s Disease

(2015) Sang-Je Park et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Streptozotocin Intracerebroventricular-Induced Neurotoxicity and Brain Insulin Resistance: a Therapeutic Intervention for Treatment of Sporadic Alzheimer’s Disease (sAD)-Like Pathology

(2015) Pradip K. Kamat et al.   MOLECULAR NEUROBIOLOGY

Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease

(2015) Zhentao Zhang et al.   Nature Communications

Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease

(2014) Maurice W. Dysken et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Oestradiol-Induced Synapse Formation in the Female Hippocampus: Roles of Oestrogen Receptor Subtypes

(2014) L. Zhou et al.   JOURNAL OF NEUROENDOCRINOLOGY

A meta-analysis of sex differences in human brain structure

(2014) Amber N.V. Ruigrok et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Magnesium Protects Cognitive Functions and Synaptic Plasticity in Streptozotocin-Induced Sporadic Alzheimer’s Model

(2014) Zhi-Peng Xu et al.   PLoS One

SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination

(2014) Hong-Bin Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracerebroventricular Streptozotocin Exacerbates Alzheimer-Like Changes of 3xTg-AD Mice

(2013) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Xanthoceraside attenuates learning and memory deficits via improving insulin signaling in STZ-induced AD rats

(2013) Peng Liu et al.   NEUROSCIENCE LETTERS

Neuroprotective effects of edaravone on cognitive deficit, oxidative stress and tau hyperphosphorylation induced by intracerebroventricular streptozotocin in rats

(2013) Shanshan Zhou et al.   NEUROTOXICOLOGY

Endocrine regulation of estrogen synthesis in the hippocampus?

(2013) Janine Prange-Kiel et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Estrogen synthesis and signaling pathways during aging: from periphery to brain

(2013) Jie Cui et al.   TRENDS IN MOLECULAR MEDICINE

What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer’s disease, about the therapeutic strategies in Alzheimer’s research

(2012) Melita Salkovic-Petrisic et al.   JOURNAL OF NEURAL TRANSMISSION

Aromatase Inhibition Abolishes LTP Generation in Female But Not in Male Mice

(2012) R. Vierk et al.   JOURNAL OF NEUROSCIENCE

A Non-transgenic Mouse Model (icv-STZ Mouse) of Alzheimer’s Disease: Similarities to and Differences from the Transgenic Model (3xTg-AD Mouse)

(2012) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Mouse models of Alzheimer's disease

(2011) Alicia M. Hall et al.   BRAIN RESEARCH BULLETIN

Insulin receptor signaling in rat hippocampus: A study in STZ (ICV) induced memory deficit model

(2011) Rahul Agrawal et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Role of estrogen receptor alpha and beta expression and signaling on cognitive function during aging

(2011) Thomas C. Foster   HIPPOCAMPUS

Estrogen-regulated synaptogenesis in the hippocampus: Sexual dimorphism in vivo but not in vitro

(2011) Lars Fester et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies

(2011) Diana W Shineman et al.   Alzheimers Research & Therapy

Alzheimer's disease, a multifactorial disorder seeking multitherapies

(2010) Khalid Iqbal et al.   Alzheimers & Dementia

Aromatase Inhibitors Induce Spine Synapse Loss in the Hippocampus of Ovariectomized Mice

(2010) Lepu Zhou et al.   ENDOCRINOLOGY

The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment

(2010) Xiaochuan Wang et al.   FASEB JOURNAL

Treadmill training restores spatial cognitive deficits and neurochemical alterations in the hippocampus of rats submitted to an intracerebroventricular administration of streptozotocin

(2010) Letícia Rodrigues et al.   JOURNAL OF NEURAL TRANSMISSION

Alzheimer's disease: clinical trials and drug development

(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence

(2010) A. Raznahan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

‘Too much good news’ – are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease?

(2010) Kathleen R. Zahs et al.   TRENDS IN NEUROSCIENCES

Structural dynamics of dendritic spines in memory and cognition

(2010) Haruo Kasai et al.   TRENDS IN NEUROSCIENCES

Dysregulation of Insulin Signaling, Glucose Transporters, O -GlcNAcylation, and Phosphorylation of Tau and Neurofilaments in the Brain

(2009) Yanqiu Deng et al.   AMERICAN JOURNAL OF PATHOLOGY

The  -Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

(2009) R. Vassar et al.   JOURNAL OF NEUROSCIENCE

Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus

(2009) Tony Valente et al.   NEUROBIOLOGY OF DISEASE

The Two Faces of Estradiol: Effects on the Developing Brain

(2009) Margaret M. McCarthy   NEUROSCIENTIST

Estrogen-induced plasticity from cells to circuits: predictions for cognitive function

(2009) Roberta Diaz Brinton   TRENDS IN PHARMACOLOGICAL SCIENCES

Diabetes and other vascular risk factors for dementia: Which factor matters most? A systematic review

(2008) Raoul P. Kloppenborg et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis

(2008) Janine Prange-Kiel et al.   JOURNAL OF CELL BIOLOGY

Failure of Neuronal Maturation in Alzheimer Disease Dentate Gyrus

(2008) Bin Li et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Role of Dickkopf-1, an Antagonist of the Wnt/ -Catenin Signaling Pathway, in Estrogen-Induced Neuroprotection and Attenuation of Tau Phosphorylation

(2008) Q.-G. Zhang et al.   JOURNAL OF NEUROSCIENCE

Effects of treadmill exercise on memory and c-Fos expression in the hippocampus of the rats with intracerebroventricular injection of streptozotocin

(2008) Yong-Seok Jee et al.   NEUROSCIENCE LETTERS

Microtubule-associated protein tau in development, degeneration and protection of neurons

(2008) Jian-Zhi Wang et al.   PROGRESS IN NEUROBIOLOGY