Metabolic Reprogramming of Macrophages Exposed to Silk, Poly(lactic-co -glycolic acid), and Silica Nanoparticles

Insights into the impact of silver nanoparticles on human keratinocytes metabolism through NMR metabolomics

(2016) Joana Carrola et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal

(2016) Evanna L. Mills et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Advances in mesoporous silica-based nanocarriers for co-delivery and combination therapy against cancer

(2016) Rafael R. Castillo et al.   Expert Opinion on Drug Delivery

Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage

(2016) Beáta Németh et al.   FASEB JOURNAL

Tumor-Associated Macrophage-Mediated Targeted Therapy of Triple-Negative Breast Cancer

(2016) Mengmeng Niu et al.   MOLECULAR PHARMACEUTICS

Emerging applications of metabolomics in drug discovery and precision medicine

(2016) David S. Wishart   NATURE REVIEWS DRUG DISCOVERY

Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1α-dependent

(2016) Lingling Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PLGA-based nanoparticles: A new paradigm in biomedical applications

(2016) Shweta Sharma et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Direct Formation of Silk Nanoparticles for Drug Delivery

(2016) Liying Xiao et al.   ACS Biomaterials-Science & Engineering

Direct Formation of Silk Nanoparticles for Drug Delivery

(2016) Liying Xiao et al.   ACS Biomaterials Science & Engineering

Carbon Nanotubes Activate Macrophages into a M1/M2 Mixed Status: Recruiting Naïve Macrophages and Supporting Angiogenesis

(2015) Jie Meng et al.   ACS Applied Materials & Interfaces

PEGylated Silk Nanoparticles for Anticancer Drug Delivery

(2015) Thidarat Wongpinyochit et al.   BIOMACROMOLECULES

Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization

(2015) Abhishek K. Jha et al.   IMMUNITY

Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression

(2015) Johannes Meiser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of the Biological Effects of a Multifunctional Nano-Drug-Carrier and Its Encapsulated Drugs

(2015) Yipeng Song et al.   JOURNAL OF PROTEOME RESEARCH

The effects of size and surface modification of amorphous silica particles on biodistribution and liver metabolism in mice

(2015) Xiaoyan Lu et al.   NANOTECHNOLOGY

A resource for cell line authentication, annotation and quality control

(2015) Mamie Yu et al.   NATURE

Contribution of metabolic reprogramming to macrophage plasticity and function

(2015) Karim C. EL Kasmi et al.   SEMINARS IN IMMUNOLOGY

Metabolomics techniques for nanotoxicity investigations

(2015) Mengying Lv et al.   Bioanalysis

Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug

(2015) Miles A. Miller et al.   Nature Communications

Silk-based biomaterials for sustained drug delivery

(2014) Tuna Yucel et al.   JOURNAL OF CONTROLLED RELEASE

Complement activation by carbon nanotubes and its influence on the phagocytosis and cytokine response by macrophages

(2014) Kirsten M. Pondman et al.   Nanomedicine-Nanotechnology Biology and Medicine

Imaging macrophages with nanoparticles

(2014) Ralph Weissleder et al.   NATURE MATERIALS

Effect of Silica Particle Size on Macrophage Inflammatory Responses

(2014) Toshimasa Kusaka et al.   PLoS One

Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

(2014) D. R. Getts et al.   Science Translational Medicine

Poly(lactide-co-glycolide)-rifampicin nanoparticles efficiently clear Mycobacterium bovis BCG infection in macrophages and remain membrane-bound in phago-lysosomes

(2013) R. Kalluru et al.   JOURNAL OF CELL SCIENCE

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production

(2013) A. Michelucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

pH-Dependent Anticancer Drug Release from Silk Nanoparticles

(2013) F. Philipp Seib et al.   Advanced Healthcare Materials

In vitro studies on the effect of particle size on macrophage responses to nanodiamond wear debris

(2012) Vinoy Thomas et al.   Acta Biomaterialia

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

Doxorubicin-loaded silk films: Drug-silk interactions and in vivo performance in human orthotopic breast cancer

(2012) F. Philipp Seib et al.   BIOMATERIALS

Physical and chemical aspects of stabilization of compounds in silk

(2012) Eleanor M. Pritchard et al.   BIOPOLYMERS

Silica-based nanoparticles for biomedical applications

(2012) Ahmad Bitar et al.   DRUG DISCOVERY TODAY

Effect size estimation: Methods and examples

(2012) Lut Berben et al.   INTERNATIONAL JOURNAL OF NURSING STUDIES

Metabolic Characterization of Leishmania major Infection in Activated and Nonactivated Macrophages.

(2012) Sabrina D. Lamour et al.   JOURNAL OF PROTEOME RESEARCH

Proof of concept for next-generation nanoparticle drugs in humans

(2012) Cormac Sheridan   NATURE BIOTECHNOLOGY

HMDB 3.0—The Human Metabolome Database in 2013

(2012) David S. Wishart et al.   NUCLEIC ACIDS RESEARCH

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

Metabolomics Studies Show Dose-Dependent Toxicity Induced by SiO2Nanoparticles in MRC-5 Human Fetal Lung Fibroblasts

(2012) Shao-Min Huang et al.   Advanced Healthcare Materials

Following dynamic biological processes through NMR-based metabonomics: A new tool in nanomedicine?

(2011) Iola F. Duarte   JOURNAL OF CONTROLLED RELEASE

Itaconic Acid Is a Mammalian Metabolite Induced during Macrophage Activation

(2011) Cheryl L. Strelko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanomedicine(s) under the Microscope

(2011) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation

(2010) J.-C. Rodriguez-Prados et al.   JOURNAL OF IMMUNOLOGY

NMR-based metabonomic analyses of the effects of ultrasmall superparamagnetic particles of iron oxide (USPIO) on macrophage metabolism

(2010) Jianghua Feng et al.   JOURNAL OF NANOPARTICLE RESEARCH

Integrated metabonomics analysis of the size-response relationship of silica nanoparticles-induced toxicity in mice

(2010) Xiaoyan Lu et al.   NANOTECHNOLOGY

New Opportunities for an Ancient Material

(2010) F. G. Omenetto et al.   SCIENCE

Biomedical applications of chemically-modified silk fibroin

(2009) Amanda R. Murphy et al.   JOURNAL OF MATERIALS CHEMISTRY

Engineered Extracellular Matrices Modulate the Expression Profile and Feeder Properties of Bone Marrow-Derived Human Multipotent Mesenchymal Stromal Cells

(2009) F. Philipp Seib et al.   TISSUE ENGINEERING PART A

Modulation of the antitumor immune response by complement

(2008) Maciej M Markiewski et al.   NATURE IMMUNOLOGY

Macrophage Responses to Silica Nanoparticles are Highly Conserved Across Particle Sizes

(2008) Katrina M. Waters et al.   TOXICOLOGICAL SCIENCES