Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-05-26
DOI
10.1038/s41598-017-02953-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions
- (2017) Pascal Kessler et al. JOURNAL OF NEUROCHEMISTRY
- MASSIF-1: a beamline dedicated to the fully automatic characterization and data collection from crystals of biological macromolecules
- (2015) Matthew W. Bowler et al. JOURNAL OF SYNCHROTRON RADIATION
- Polypharmacology profiles and phylogenetic analysis of three-finger toxins from mamba venom: Case of aminergic toxins
- (2014) Guillaume Blanchet et al. BIOCHIMIE
- Ancestral mutations as a tool for solubilizing proteins: The case of a hydrophobic phosphate-binding protein
- (2014) Daniel Gonzalez et al. FEBS Open Bio
- Crystallization of recombinant green mamba ρ-Da1a toxin during a lyophilization procedure and its structure determination
- (2013) Arhamatoulaye Maïga et al. Acta Crystallographica Section F-Structural Biology and Crystallization Communications
- Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor
- (2013) C. Petrel et al. BIOCHEMICAL PHARMACOLOGY
- Directed evolution of three-finger toxin to produce serine protease inhibitors
- (2013) Weiyan Cai et al. JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION
- Evolutionary biochemistry: revealing the historical and physical causes of protein properties
- (2013) Michael J. Harms et al. NATURE REVIEWS GENETICS
- Orthosteric Binding of ρ-Da1a, a Natural Peptide of Snake Venom Interacting Selectively with the α1A-Adrenoceptor
- (2013) Arhamatoulaye Maïga et al. PLoS One
- Conservation of Protein Structure over Four Billion Years
- (2013) Alvaro Ingles-Prieto et al. STRUCTURE
- New α-adrenergic property for synthetic MTβ and CM-3 three-finger fold toxins from black mamba
- (2013) Guillaume Blanchet et al. TOXICON
- Engineering of Three-Finger Fold Toxins Creates Ligands with Original Pharmacological Profiles for Muscarinic and Adrenergic Receptors
- (2012) Carole Fruchart-Gaillard et al. PLoS One
- Non-enzymatic proteins from snake venoms: A gold mine of pharmacological tools and drug leads
- (2012) Ryan J.R. McCleary et al. TOXICON
- Complex cocktails: the evolutionary novelty of venoms
- (2012) Nicholas R. Casewell et al. TRENDS IN ECOLOGY & EVOLUTION
- REFMAC5 for the refinement of macromolecular crystal structures
- (2011) Garib N. Murshudov et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Dissecting Protein−Protein Interactions Using Directed Evolution
- (2011) Daniel A. Bonsor et al. BIOCHEMISTRY
- Venoms as a platform for human drugs: translating toxins into therapeutics
- (2011) Glenn F King EXPERT OPINION ON BIOLOGICAL THERAPY
- MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods
- (2011) K. Tamura et al. MOLECULAR BIOLOGY AND EVOLUTION
- Muscarinic toxins
- (2011) Denis Servent et al. TOXICON
- G protein-coupled receptors, an unexploited animal toxin targets: Exploration of green mamba venom for novel drug candidates active against adrenoceptors
- (2011) Arhamatoulaye Maïga et al. TOXICON
- Directed evolution of a three-finger neurotoxin by using cDNA display yields antagonists as well as agonists of interleukin-6 receptor signaling
- (2011) Mohammed Naimuddin et al. Molecular Brain
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors
- (2010) Céline Rouget et al. BRITISH JOURNAL OF PHARMACOLOGY
- Beyond directed evolution—semi-rational protein engineering and design
- (2010) Stefan Lutz CURRENT OPINION IN BIOTECHNOLOGY
- Analyzing protein structure and function using ancestral gene reconstruction
- (2010) Michael J Harms et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Exploiting Models of Molecular Evolution to Efficiently Direct Protein Engineering
- (2010) Megan F. Cole et al. JOURNAL OF MOLECULAR EVOLUTION
- Reconstructed evolutionary adaptive paths give polymerases accepting reversible terminators for sequencing and SNP detection
- (2010) F. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The three-finger toxin MTα is a selective α2B-adrenoceptor antagonist
- (2010) Katja Koivula et al. TOXICON
- The development of Byetta (exenatide) from the venom of the Gila monster as an anti-diabetic agent
- (2010) Brian L. Furman TOXICON
- The Toxicogenomic Multiverse: Convergent Recruitment of Proteins Into Animal Venoms
- (2009) Bryan G. Fry et al. Annual Review of Genomics and Human Genetics
- Jalview Version 2--a multiple sequence alignment editor and analysis workbench
- (2009) A. M. Waterhouse et al. BIOINFORMATICS
- Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α1A-adrenoceptor
- (2009) L Quinton et al. BRITISH JOURNAL OF PHARMACOLOGY
- Muscarinic toxins: tools for the study of the pharmacological and functional properties of muscarinic receptors
- (2009) Denis Servent et al. JOURNAL OF NEUROCHEMISTRY
- Conopressin-T fromConus tulipaReveals an Antagonist Switch in Vasopressin-like Peptides
- (2008) Sébastien Dutertre et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Different Interactions between MT7 Toxin and the Human Muscarinic M1 Receptor in Its Free and N-Methylscopolamine-Occupied States
- (2008) C. Fruchart-Gaillard et al. MOLECULAR PHARMACOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started