Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria

Pancreatic Protein Tyrosine Phosphatase 1B Deficiency Exacerbates Acute Pancreatitis in Mice

(2016) Ahmed Bettaieb et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus

(2016) Jianxun Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture

(2016) L. A. New et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases

(2016) Ying-Nan P. Chen et al.   NATURE

Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2

(2016) Khalil El Karoui et al.   Nature Communications

Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury

(2015) Rakesh Verma et al.   MOLECULAR AND CELLULAR BIOLOGY

Protein Tyrosine Phosphatase 1B Inhibition Protects against Podocyte Injury and Proteinuria

(2014) Takanori Kumagai et al.   AMERICAN JOURNAL OF PATHOLOGY

Increased SHP-1 Protein Expression by High Glucose Levels Reduces Nephrin Phosphorylation in Podocytes

(2014) Benoit Denhez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine phosphatase SHP2 increases cell motility in triple-negative breast cancer through the activation of SRC-family kinases

(2014) N Sausgruber et al.   ONCOGENE

Effects of Soluble Epoxide Hydrolase Deficiency on Acute Pancreatitis in Mice

(2014) Ahmed Bettaieb et al.   PLoS One

Epithelial Tyrosine Phosphatase SHP-2 Protects against Intestinal Inflammation in Mice

(2013) G. Coulombe et al.   MOLECULAR AND CELLULAR BIOLOGY

The Tyrosine Phosphatase SHP2 Regulates Focal Adhesion Kinase to Promote EGF-Induced Lamellipodia Persistence and Cell Migration

(2013) Zachary R. Hartman et al.   MOLECULAR CANCER RESEARCH

The podocyte slit diaphragm—from a thin grey line to a complex signalling hub

(2013) Florian Grahammer et al.   Nature Reviews Nephrology

Hepatic Src Homology Phosphatase 2 Regulates Energy Balance in Mice

(2012) Naoto Nagata et al.   ENDOCRINOLOGY

Small molecule tools for functional interrogation of protein tyrosine phosphatases

(2012) Rongjun He et al.   FEBS Journal

Shp2 Plays an Important Role in Acute Cigarette Smoke-Mediated Lung Inflammation

(2012) F.-f. Li et al.   JOURNAL OF IMMUNOLOGY

The intersecting roles of endoplasmic reticulum stress, ubiquitin–proteasome system, and autophagy in the pathogenesis of proteinuric kidney disease

(2012) Andrey V. Cybulsky   KIDNEY INTERNATIONAL

Amelioration of Acute Kidney Injury in Lipopolysaccharide-Induced Systemic Inflammatory Response Syndrome by an Aldose Reductase Inhibitor, Fidarestat

(2012) Kazunori Takahashi et al.   PLoS One

LPS-Induced Murine Systemic Inflammation Is Driven by Parenchymal Cell Activation and Exclusively Predicted by Early MCP-1 Plasma Levels

(2011) Justin E. Juskewitch et al.   AMERICAN JOURNAL OF PATHOLOGY

Cell Biology and Pathology of Podocytes

(2011) Anna Greka et al.   Annual Review of Physiology

Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis

(2011) Emilie A. Bard-Chapeau et al.   CANCER CELL

TLR-signaling Networks

(2010) J. Brown et al.   JOURNAL OF DENTAL RESEARCH

Inhibition of Podocyte FAK Protects against Proteinuria and Foot Process Effacement

(2010) H. Ma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NF- B in Renal Inflammation

(2010) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

SHP2 Mediates the Localized Activation of Fyn Downstream of the  6 4 Integrin To Promote Carcinoma Invasion

(2010) X. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Endoplasmic reticulum stress in proteinuric kidney disease

(2009) Andrey V. Cybulsky   KIDNEY INTERNATIONAL

The role of stress-activated protein kinase signaling in renal pathophysiology

(2008) F.Y. Ma et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

The tyrosine phosphatase Shp2 (PTPN11) in cancer

(2008) Gordon Chan et al.   CANCER AND METASTASIS REVIEWS

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

(2008) Christian Faul et al.   NATURE MEDICINE