Epithelial Tyrosine Phosphatase SHP-2 Protects against Intestinal Inflammation in Mice

Tight junctions on the move: molecular mechanisms for epithelial barrier regulation

(2012) Le Shen   Annals of the New York Academy of Sciences

Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway

(2012) Loredana Petecchia et al.   LABORATORY INVESTIGATION

PTPN2 Gene Variants Are Associated with Susceptibility to Both Crohn's Disease and Ulcerative Colitis Supporting a Common Genetic Disease Background

(2012) Jürgen Glas et al.   PLoS One

Expression profiling of claudins in the human gastrointestinal tract in health and during inflammatory bowel disease

(2012) Anke L. Lameris et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Constitutive activation of the MEK/ERK pathway inhibits intestinal epithelial cell differentiation

(2011) Etienne Lemieux et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Ptpn11/Shp2 Acts as a Tumor Suppressor in Hepatocellular Carcinogenesis

(2011) Emilie A. Bard-Chapeau et al.   CANCER CELL

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

NF-κB in the regulation of epithelial homeostasis and inflammation

(2010) Andy Wullaert et al.   CELL RESEARCH

Cdx2 regulates endo-lysosomal function and epithelial cell polarity

(2010) N. Gao et al.   GENES & DEVELOPMENT

The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models

(2010) Sandra Nell et al.   NATURE REVIEWS MICROBIOLOGY

Increased Susceptibility to Dextran Sulfate Sodium Induced Colitis in the T Cell Protein Tyrosine Phosphatase Heterozygous Mouse

(2010) Syed-Wajahat Hassan et al.   PLoS One

Expression of interleukin 6 in brain and colon of rats with TNBS-induced colitis

(2010) Kai Wang   WORLD JOURNAL OF GASTROENTEROLOGY

IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer

(2009) Sergei Grivennikov et al.   CANCER CELL

Epithelial phosphatase and tensin homolog regulates intestinal architecture and secretory cell commitment and acts as a modifier gene in neoplasia

(2009) Marie-Josée Langlois et al.   FASEB JOURNAL

Constitutively active MEK1 is sufficient to induce epithelial-to-mesenchymal transition in intestinal epithelial cells and to promote tumor invasion and metastasis

(2009) Étienne Lemieux et al.   INTERNATIONAL JOURNAL OF CANCER

E2F4 expression is required for cell cycle progression of normal intestinal crypt cells and colorectal cancer cells

(2009) Hugo Garneau et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Polymorphisms of PTPN11 Coding SHP-2 as Biomarkers for Ulcerative Colitis Susceptibility in the Japanese Population

(2009) Yukiko Narumi et al.   JOURNAL OF CLINICAL IMMUNOLOGY

STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

(2009) Geethanjali Pickert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microbial Influences in Inflammatory Bowel Diseases

(2008) R. Balfour Sartor   GASTROENTEROLOGY

Commensal DNA Limits Regulatory T Cell Conversion and Is a Natural Adjuvant of Intestinal Immune Responses

(2008) Jason A. Hall et al.   IMMUNITY

Intestinal barrier dysfunction in inflammatory bowel diseases

(2008) Michael A. McGuckin et al.   INFLAMMATORY BOWEL DISEASES

Crosstalk of tight junction components with signaling pathways

(2007) Lorenza González-Mariscal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway

(2007) Marie Dance et al.   CELLULAR SIGNALLING