Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis

Cardiac Fibrosis Revisited by MicroRNA Therapeutics

(2012) Thomas Thum et al.   CIRCULATION

TGF-β upregulates miR-181a expression to promote breast cancer metastasis

(2012) Molly A. Taylor et al.   JOURNAL OF CLINICAL INVESTIGATION

Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin αVβ3 engagement and PI3K/pAkt/NFκB signaling

(2011) Raquel Urtasun et al.   HEPATOLOGY

MicroRNAs as mediators and therapeutic targets in chronic kidney disease

(2011) Johan M. Lorenzen et al.   Nature Reviews Nephrology

Circulating levels of osteopontin are closely related to glomerular filtration rate and cardiovascular risk markers in patients with chronic kidney disease

(2010) Johan Lorenzen et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Angiotensin II receptor blocker and statins lower elevated levels of osteopontin in essential hypertension—Results from the EUTOPIA trial

(2009) Johan M. Lorenzen et al.   ATHEROSCLEROSIS

Downregulating osteopontin reduces angiotensin II-induced inflammatory activation in vascular smooth muscle cells

(2009) B. L. Yin et al.   INFLAMMATION RESEARCH

Osteopontin modulates angiotensin II–induced inflammation, oxidative stress, and fibrosis of the kidney

(2009) Talya Wolak et al.   KIDNEY INTERNATIONAL

Osteopontin, a New Prognostic Biomarker in Patients With Chronic Heart Failure

(2008) Mark Rosenberg et al.   Circulation-Heart Failure

Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring

(2008) Ryoichi Mori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

miR-21 Gene Expression Triggered by AP-1 Is Sustained through a Double-Negative Feedback Mechanism

(2008) Shuji Fujita et al.   JOURNAL OF MOLECULAR BIOLOGY

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

(2008) Thomas Thum et al.   NATURE

Osteopontin Expression Is Required for Myofibroblast Differentiation

(2007) Yair Lenga et al.   CIRCULATION RESEARCH