Activation of PKA in cell requires higher concentration of cAMP than in vitro: implications for compartmentalization of cAMP signalling

FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility

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Fourth-Generation Epac-Based FRET Sensors for cAMP Feature Exceptional Brightness, Photostability and Dynamic Range: Characterization of Dedicated Sensors for FLIM, for Ratiometry and with High Affinity

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Characterization of contracting cardiomyocyte colonies in the primary culture of neonatal rat myocardial cells: A model of in vitro cardiomyogenesis

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Advances in targeting cyclic nucleotide phosphodiesterases

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Cardiac Myocyte Z-Line Calmodulin Is Mainly RyR2-Bound, and Reduction Is Arrhythmogenic and Occurs in Heart Failure

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Cyclic AMP compartments and signaling specificity: Role of cyclic nucleotide phosphodiesterases

(2013) Marco Conti et al.   JOURNAL OF GENERAL PHYSIOLOGY

PKA and PDE4D3 anchoring to AKAP9 provides distinct regulation of cAMP signals at the centrosome

(2012) Anna Terrin et al.   JOURNAL OF CELL BIOLOGY

cGMP Signals Modulate cAMP Levels in a Compartment-Specific Manner to Regulate Catecholamine-Dependent Signaling in Cardiac Myocytes

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Spatial control of cAMP signalling in health and disease

(2011) Manuela Zaccolo   CURRENT OPINION IN PHARMACOLOGY

PDEs create local domains of cAMP signaling

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FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

(2011) Sebastian Börner et al.   Nature Protocols

A-Kinase Anchoring Proteins

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Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown

(2009) Miles D. Houslay   TRENDS IN BIOCHEMICAL SCIENCES

Cytoplasmic cAMP concentrations in intact cardiac myocytes

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Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog

(2008) Daniela Moll et al.   BMC BIOCHEMISTRY

Protein Kinase A Type I and Type II Define Distinct Intracellular Signaling Compartments

(2008) Giulietta Di Benedetto et al.   CIRCULATION RESEARCH