Synthesis and antimicrobial evaluation of promising 7-arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates and their halogenated amino compounds for treating Gram-negative bacterial infections

Design, synthesis and biological evaluation of 5-fluorouracil-derived benzimidazoles as novel type of potential antimicrobial agents

(2016) Xue-Jie Fang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Antibacterial Meroterpenoids from the South China Sea Sponge Dysidea sp.

(2016) Xia Zhang et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Synthesis and antimalarial activity of quinones and structurally-related oxirane derivatives

(2016) Paula F. Carneiro et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of diaziridinyl quinone isoxazole hybrids

(2016) K. Jones M. Swapnaja et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Anthraquinones As Pharmacological Tools and Drugs

(2016) Enas M. Malik et al.   MEDICINAL RESEARCH REVIEWS

Naphthohydroquinones, naphthoquinones, anthraquinones, and a naphthohydroquinone dimer isolated from the aerial parts of Morinda parvifolia and their cytotoxic effects through up-regulation of p53

(2016) Jie Kang et al.   PHYTOCHEMISTRY

Etiologic Agents of Bacterial Sepsis and Their Antibiotic Susceptibility Patterns among Patients Living with Human Immunodeficiency Virus at Gondar University Teaching Hospital, Northwest Ethiopia

(2016) Gelila Alebachew et al.   Biomed Research International

Role of the Outer Membrane and Porins in Susceptibility of β-Lactamase-Producing Enterobacteriaceae to Ceftazidime-Avibactam

(2015) Jean-Marie Pagès et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial Resistance in Hospital-Acquired Gram-Negative Bacterial Infections

(2015) Borna Mehrad et al.   CHEST

The Challenge of Efflux-Mediated Antibiotic Resistance in Gram-Negative Bacteria

(2015) Xian-Zhi Li et al.   CLINICAL MICROBIOLOGY REVIEWS

New antibiotics and antimicrobial combination therapy for the treatment of gram-negative bacterial infections

(2015) Matteo Bassetti et al.   Current Opinion in Critical Care

Agents that inhibit bacterial biofilm formation

(2015) Nira Rabin et al.   Future Medicinal Chemistry

Antibiotic Discovery: Combatting Bacterial Resistance in Cells and in Biofilm Communities

(2015) Anahit Penesyan et al.   MOLECULES

Infections Caused by Resistant Gram-Negative Bacteria: Epidemiology and Management

(2015) Keith S. Kaye et al.   PHARMACOTHERAPY

Synthesis of a new class of naphthoquinone glycoconjugates and evaluation of their potential as antitumoral agents

(2015) Vinicius R. Campos et al.   RSC Advances

Mechanisms of antimicrobial resistance in Gram-negative bacilli

(2015) Étienne Ruppé et al.   Annals of Intensive Care

Role of small colony variants in persistence of Pseudomonas aeruginosa infections in cystic fibrosis lungs

(2015) Jacob Malone   Infection and Drug Resistance

Synthesis, molecular docking and cytotoxicity evaluation of novel 2-(4-amino-benzosulfonyl)-5H-benzo[b]carbazole-6,11-dione derivatives as histone deacetylase (HDAC8) inhibitors

(2014) P. Ravichandiran et al.   BIOORGANIC CHEMISTRY

Catheter-Associated Urinary Tract Infection by Pseudomonas aeruginosa Is Mediated by Exopolysaccharide-Independent Biofilms

(2014) Stephanie J. Cole et al.   INFECTION AND IMMUNITY

Chemistry: Chemical con artists foil drug discovery

(2014) Jonathan Baell et al.   NATURE

In vitro and in vivo analysis of the antithrombotic and toxicological profile of new antiplatelets N-acylhydrazone derivatives and development of nanosystems

(2014) Plínio Cunha Sathler et al.   THROMBOSIS RESEARCH

Synthesis and antifungal evaluation of 7-arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates

(2013) Chung-Kyu Ryu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis using microwave irradiation and antibacterial evaluation of new N,O-acetals and N,S-acetals derived from 2-amino-1,4-naphthoquinones

(2013) Alessandro K. Jordão et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antifungal activity of terpenyl-1,4-naphthoquinone and 1,4-anthracenedione derivatives

(2013) Ma Ángeles Castro et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

β-Lapachone activity in synergy with conventional antimicrobials against methicillin resistant Staphylococcus aureus strains

(2013) L. Macedo et al.   PHYTOMEDICINE

The Naphthoquinone Diospyrin Is an Inhibitor of DNA Gyrase with a Novel Mechanism of Action

(2012) Shantanu Karkare et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rules for Identifying Potentially Reactive or Promiscuous Compounds

(2012) Robert F. Bruns et al.   JOURNAL OF MEDICINAL CHEMISTRY

Poly(2-ethyl-2-oxazoline) as Alternative for the Stealth Polymer Poly(ethylene glycol): Comparison of in vitro Cytotoxicity and Hemocompatibility

(2012) Marius Bauer et al.   MACROMOLECULAR BIOSCIENCE

Quinoline: A versatile heterocyclic

(2012) Akranth Marella et al.   SAUDI PHARMACEUTICAL JOURNAL

Synthesis of carbohydrate-based naphthoquinones and their substituted phenylhydrazono derivatives as anticancer agents

(2012) Vinicius R. Campos et al.   RSC Advances

Antibacterial activity against β- lactamase producing Methicillin and Ampicillin-resistants Staphylococcus aureus: fractional Inhibitory Concentration Index (FICI) determination

(2012) Kiessoun Konaté et al.   Annals of Clinical Microbiology and Antimicrobials

The Chemical Biology of Naphthoquinones and Its Environmental Implications

(2011) Yoshito Kumagai et al.   Annual Review of Pharmacology and Toxicology

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance

(2011) A.-P. Magiorakos et al.   CLINICAL MICROBIOLOGY AND INFECTION

Synthesis and biological evaluation of novel nitrogen- and sulfur-containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents

(2011) Cemil Ibis et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Abenquines A–D: aminoquinone derivatives produced by Streptomyces sp. strain DB634

(2011) Dirk Schulz et al.   JOURNAL OF ANTIBIOTICS

Bacteriostatic versus bactericidal activity of ciprofloxacin in Escherichia coli assessed by flow cytometry using a novel far-red dye

(2011) Filomena Silva et al.   JOURNAL OF ANTIBIOTICS

The crisis of no new antibiotics—what is the way forward?

(2011) Laura JV Piddock   LANCET INFECTIOUS DISEASES

Antiviral agents 2. Synthesis of trimeric naphthoquinone analogues of conocurvone and their antiviral evaluation against HIV

(2010) Ian T. Crosby et al.   BIOORGANIC & MEDICINAL CHEMISTRY

El problema creciente de la resistencia antibiótica en bacilos gramnegativos: situación actual

(2010) Luis Martínez-Martínez et al.   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

Observations on screening-based research and some concerning trends in the literature

(2010) Jonathan B Baell   Future Medicinal Chemistry

Current state of coenzyme Q10 production and its applications

(2009) Marimuthu Jeya et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Studies on quinones. Part 45: Novel 7-aminoisoquinoline-5,8-quinone derivatives with antitumor properties on cancer cell lines

(2009) Jaime A. Valderrama et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents

(2009) Vishnu K. Tandon et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY