Dietary Metabolites and Chronic Kidney Disease

Glycative Stress and Its Defense Machinery Glyoxalase 1 in Renal Pathogenesis

(2017) Yosuke Hirakawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Very Low-Protein Diet (VLPD) Reduces Metabolic Acidosis in Subjects with Chronic Kidney Disease: The “Nutritional Light Signal” of the Renal Acid Load

(2017) Biagio Di Iorio et al.   Nutrients

Approach to the Treatment of Chronic Metabolic Acidosis in CKD

(2016) Kalani L. Raphael   AMERICAN JOURNAL OF KIDNEY DISEASES

Metabolic Acidosis of CKD: An Update

(2016) Jeffrey A. Kraut et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Bicarbonate Concentration, Acid-Base Status, and Mortality in the Health, Aging, and Body Composition Study

(2016) K. L. Raphael et al.   Clinical Journal of the American Society of Nephrology

RAGE and glyoxalase in kidney disease

(2016) Reiko Inagi   GLYCOCONJUGATE JOURNAL

Correction of metabolic acidosis improves insulin resistance in chronic kidney disease

(2016) Antonio Bellasi et al.   BMC Nephrology

Diets for patients with chronic kidney disease, should we reconsider?

(2016) William E. Mitch et al.   BMC Nephrology

The effects of AST-120 on chronic kidney disease progression in the United States of America: a post hoc subgroup analysis of randomized controlled trials

(2016) Gerald Schulman et al.   BMC Nephrology

Chiral amino acid metabolomics for novel biomarker screening in the prognosis of chronic kidney disease

(2016) Tomonori Kimura et al.   Scientific Reports

Dietary Acid Load and Incident Chronic Kidney Disease: Results from the ARIC Study

(2015) Casey M. Rebholz et al.   AMERICAN JOURNAL OF NEPHROLOGY

Role of Uremic Toxins in Erythropoiesis-Stimulating Agent Resistance in Chronic Kidney Disease and Dialysis Patients

(2015) Masaomi Nangaku et al.   JOURNAL OF RENAL NUTRITION

Uremic Toxicity of Advanced Glycation End Products in CKD

(2015) A. E. M. Stinghen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Probiotics and chronic kidney disease

(2015) Laetitia Koppe et al.   KIDNEY INTERNATIONAL

D-Amino-Acid Oxidase Inhibition Increases D-Serine Plasma Levels in Mouse But not in Monkey or Dog

(2015) Camilo Rojas et al.   NEUROPSYCHOPHARMACOLOGY

Glyoxalase I reduces glycative and oxidative stress and prevents age-related endothelial dysfunction through modulation of endothelial nitric oxide synthase phosphorylation

(2014) Airi Jo-Watanabe et al.   AGING CELL

Glycative stress and glyoxalase in kidney disease and aging: Figure 1

(2014) Reiko Inagi   BIOCHEMICAL SOCIETY TRANSACTIONS

The Association between a Mediterranean-Style Diet and Kidney Function in the Northern Manhattan Study Cohort

(2014) M. Khatri et al.   Clinical Journal of the American Society of Nephrology

Irbesartan inhibits advanced glycation end product-induced increase in asymmetric dimethylarginine level in mesangial cells through its anti-oxidative properties

(2014) Yuji Ishibashi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Effects of Italian Mediterranean organic diet vs. low-protein diet in nephropathic patients according to MTHFR genotypes

(2014) Nicola Di Daniele et al.   JOURNAL OF NEPHROLOGY

Alteration of the Intestinal Environment by Lubiprostone Is Associated with Amelioration of Adenine-Induced CKD

(2014) E. Mishima et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Randomized Placebo-Controlled EPPIC Trials of AST-120 in CKD

(2014) G. Schulman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

What Would You Like to Eat, Mr CKD Microbiota? A Mediterranean Diet, please!

(2014) Eustacchio Montemurno et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Proteostasis in endoplasmic reticulum—new mechanisms in kidney disease

(2014) Reiko Inagi et al.   Nature Reviews Nephrology

Ischemic Acute Kidney Injury Perturbs Homeostasis of Serine Enantiomers in the Body Fluid in Mice: Early Detection of Renal Dysfunction Using the Ratio of Serine Enantiomers

(2014) Jumpei Sasabe et al.   PLoS One

A Receptor-Based Bioadsorbent to Target Advanced Glycation End Products in Chronic Kidney Disease

(2013) Yangrong Zhang et al.   ARTIFICIAL ORGANS

Benzoate, a D-Amino Acid Oxidase Inhibitor, for the Treatment of Early-Phase Alzheimer Disease: A Randomized, Double-Blind, Placebo-Controlled Trial

(2013) Chieh-Hsin Lin et al.   BIOLOGICAL PSYCHIATRY

Very Low Protein Diet Reduces Indoxyl Sulfate Levels in Chronic Kidney Disease

(2013) Stefania Marzocco et al.   BLOOD PURIFICATION

Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling

(2013) Jun Liu et al.   CELLULAR SIGNALLING

Mediterranean Diet, Kidney Function, and Mortality in Men with CKD

(2013) X. Huang et al.   Clinical Journal of the American Society of Nephrology

Glyoxalase-1 overexpression reduces endothelial dysfunction and attenuates early renal impairment in a rat model of diabetes

(2013) Olaf Brouwers et al.   DIABETOLOGIA

Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity

(2013) Md. Abdul Hye Khan et al.   FASEB JOURNAL

Advanced glycation endproducts in food and their effects on health

(2013) Malene W. Poulsen et al.   FOOD AND CHEMICAL TOXICOLOGY

Targeting the transcription factor Nrf2 to ameliorate oxidative stress and inflammation in chronic kidney disease

(2013) Stacey Ruiz et al.   KIDNEY INTERNATIONAL

Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease

(2013) Dick de Zeeuw et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial DNA Damage via Augmented Oxidative Stress Regulates Endoplasmic Reticulum Stress and Autophagy: Crosstalk, Links and Signaling

(2013) Larysa V. Yuzefovych et al.   PLoS One

Indoxyl sulfate, a uremic toxin, downregulates renal expression of Nrf2 through activation of NF-κB

(2013) Dilinaer Bolati et al.   BMC Nephrology

Stat3 Contributes to Indoxyl Sulfate-Induced Inflammatory and Fibrotic Gene Expression and Cellular Senescence

(2012) Hidehisa Shimizu et al.   AMERICAN JOURNAL OF NEPHROLOGY

Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress

(2012) Gulinuer Muteliefu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications

(2012) R. Nagai et al.   DIABETES

Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation

(2012) Chiao-Yin Sun et al.   KIDNEY INTERNATIONAL

Serum and adipose tissue fatty acid composition as biomarkers of habitual dietary fat intake in elderly men with chronic kidney disease

(2012) Xiaoyan Huang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Uremic Toxins Induce Kidney Fibrosis by Activating Intrarenal Renin–Angiotensin–Aldosterone System Associated Epithelial-to-Mesenchymal Transition

(2012) Chiao-Yin Sun et al.   PLoS One

Dietary Omega-3 Fatty Acid, Ratio of Omega-6 to Omega-3 Intake, Inflammation, and Survival in Long-term Hemodialysis Patients

(2011) Nazanin Noori et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Glyoxalase I Retards Renal Senescence

(2011) Yoichiro Ikeda et al.   AMERICAN JOURNAL OF PATHOLOGY

Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation

(2011) Mingzhan Xue et al.   BIOCHEMICAL JOURNAL

Serum Levels of Phosphorus, Parathyroid Hormone, and Calcium and Risks of Death and Cardiovascular Disease in Individuals With Chronic Kidney Disease

(2011) Suetonia C. Palmer   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Dysregulated Oxygen Metabolism of the Kidney by Uremic Toxins: Review

(2011) Chih-Kang Chiang et al.   JOURNAL OF RENAL NUTRITION

Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner

(2011) Chih-Kang Chiang et al.   LABORATORY INVESTIGATION

Bardoxolone Methyl and Kidney Function in CKD with Type 2 Diabetes

(2011) Pablo E. Pergola et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oleate and eicosapentaenoic acid attenuate palmitate-induced inflammation and apoptosis in renal proximal tubular cell

(2010) Mariko Soumura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deletion of the Receptor for Advanced Glycation End Products Reduces Glomerulosclerosis and Preserves Renal Function in the Diabetic OVE26 Mouse

(2010) Nina Reiniger et al.   DIABETES

Advanced Glycation End Products in Foods and a Practical Guide to Their Reduction in the Diet

(2010) Jaime Uribarri et al.   JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION

Nutrition and Growth in Kidney Disease

(2010) CAROL POLLOCK et al.   NEPHROLOGY

p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease

(2010) I.-W. Wu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effect of a Carbonaceous Oral Adsorbent on the Progression of CKD: A Multicenter, Randomized, Controlled Trial

(2009) Tadao Akizawa et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Protection against Loss of Innate Defenses in Adulthood by Low Advanced Glycation End Products (AGE) Intake: Role of the Antiinflammatory AGE Receptor-1

(2009) Helen Vlassara et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes

(2009) M. T. Coughlan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Effect of a Very Low-Protein Diet on Outcomes: Long-term Follow-up of the Modification of Diet in Renal Disease (MDRD) Study

(2008) Vandana Menon et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

The Role of Advanced Glycation End Products in Progression and Complications of Diabetes

(2008) Su-Yen Goh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake

(2008) Leanne Hodson et al.   PROGRESS IN LIPID RESEARCH