A2B adenosine receptor agonist induces cell cycle arrest and apoptosis in breast cancer stem cells via ERK1/2 phosphorylation

A3 adenosine receptor agonist induce G1 cell cycle arrest via Cyclin D and cyclin-dependent kinase 4 pathways in OVCAR-3 and Caov-4 cell lines

(2017) Mahmoud Aghaei et al.   Journal of Cancer Research and Therapeutics

A3 Adenosine Receptor Agonist Inhibited Survival of Breast Cancer Stem Cells via GLI-1 and ERK1/2 Pathway

(2017) Seyyed Mehdi Jafari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Breast cancer metastasis: Putative therapeutic role of vascular cell adhesion molecule-1

(2017) Rohit Sharma et al.   CELLULAR ONCOLOGY

Targeting Cellular Signaling Pathways in Breast Cancer Stem Cells and its Implication for Cancer Treatment

(2016) BRUNO RICARDO BARRETO PIRES et al.   ANTICANCER RESEARCH

Adenosine 2B Receptor Expression on Cancer Cells Promotes Metastasis

(2016) D. Mittal et al.   CANCER RESEARCH

Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population

(2016) Carmela Ciccarelli et al.   Molecular Cancer

Adenosine as a Multi-Signalling Guardian Angel in Human Diseases: When, Where and How Does it Exert its Protective Effects?

(2016) Pier Andrea Borea et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Activation of A2b adenosine receptor regulates ovarian cancer cell growth: involvement of Bax/Bcl-2 and caspase-3

(2015) Sima Hajiahmadi et al.   Biochemistry and Cell Biology

Adenosine signaling promotes hematopoietic stem and progenitor cell emergence

(2015) Lili Jing et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis

(2015) C M Aherne et al.   Mucosal Immunology

The Rab2A GTPase Promotes Breast Cancer Stem Cells and Tumorigenesis via Erk Signaling Activation

(2015) Man-Li Luo et al.   Cell Reports

Blockade of A2b Adenosine Receptor Reduces Tumor Growth and Immune Suppression Mediated by Myeloid-Derived Suppressor Cells in a Mouse Model of Melanoma

(2015) Raffaella Iannone et al.   NEOPLASIA

Reduced tumorigenicity and drug resistance through the downregulation of octamer-binding protein 4 and Nanog transcriptional factor expression in human breast stem cells

(2014) ZHENG-JIE HUANG et al.   Molecular Medicine Reports

Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells

(2014) Maryam Hamzeloo-Moghadam et al.   TUMOR BIOLOGY

Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy

(2014) S Daniele et al.   Cell Death & Disease

DNMT3A mutations and clinical features in Chinese patients with acute myeloid leukemia

(2013) Quanyi Lu et al.   Cancer Cell International

Cell cycle regulators cyclin D1 and CDK4/6 have estrogen receptor-dependent divergent functions in breast cancer migration and stem cell-like activity

(2013) Rebecca Lamb et al.   CELL CYCLE

Extracellular Adenosine Sensing—A Metabolic Cell Death Priming Mechanism Downstream of p53

(2013) Jaclyn S. Long et al.   MOLECULAR CELL

Propagation of Human Prostate Cancer Stem-Like Cells Occurs through EGFR-Mediated ERK Activation

(2013) Adrian P. Rybak et al.   PLoS One

A2B adenosine receptor blockade inhibits growth of prostate cancer cells

(2013) Qiang Wei et al.   Purinergic Signalling

A possible usage of a CDK4 inhibitor for breast cancer stem cell-targeted therapy

(2012) Yu Kyeong Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Significance of CD44 and CD24 as Cancer Stem Cell Markers: An Enduring Ambiguity

(2012) Appalaraju Jaggupilli et al.   Clinical & Developmental Immunology

Breast cancer stem cells

(2012) Marco A. Velasco-Velázquez et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Antagonism of miR-21 Reverses Epithelial-Mesenchymal Transition and Cancer Stem Cell Phenotype through AKT/ERK1/2 Inactivation by Targeting PTEN

(2012) Mingli Han et al.   PLoS One

The Role of Breast Cancer Stem Cells in Metastasis and Therapeutic Implications

(2011) Marco A. Velasco-Velázquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Caspases and cancer

(2011) M Olsson et al.   CELL DEATH AND DIFFERENTIATION

Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway

(2011) Mahmoud Aghaei et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Adenosine A2B Receptor Blockade Slows Growth of Bladder and Breast Tumors

(2011) C. Cekic et al.   JOURNAL OF IMMUNOLOGY

Downregulation of CD44 reduces doxorubicin resistance of CD44+CD24- breast cancer cells

(2011) Pham Van Phuc et al.   OncoTargets and Therapy

Activation of Akt and MAPK pathways enhances the tumorigenicity of CD133+ primary colon cancer cells

(2010) Y. K. Wang et al.   CARCINOGENESIS

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

(2010) Yohannes Mebratu et al.   CELL CYCLE

Cancer Stem Cells and Self-renewal

(2010) C. A. O'Brien et al.   CLINICAL CANCER RESEARCH

CD133+ liver cancer stem cells from methionine adenosyl transferase 1A-deficient mice demonstrate resistance to transforming growth factor (TGF)-β-induced apoptosis

(2008) Wei Ding et al.   HEPATOLOGY

Bcl-2 family proteins and cancer

(2008) K W Yip et al.   ONCOGENE