Breast cancer metastasis: Putative therapeutic role of vascular cell adhesion molecule-1

High-density lipoprotein of patients with breast cancer complicated with type 2 diabetes mellitus promotes cancer cells adhesion to vascular endothelium via ICAM-1 and VCAM-1 upregulation

(2016) Xiaoqin Huang et al.   BREAST CANCER RESEARCH AND TREATMENT

Hydrophobic interaction mediating self-assembled nanoparticles of succinobucol suppress lung metastasis of breast cancer by inhibition of VCAM-1 expression

(2015) Haiqiang Cao et al.   JOURNAL OF CONTROLLED RELEASE

Leukocyte integrins: Role in leukocyte recruitment and as therapeutic targets in inflammatory disease

(2015) Ioannis Mitroulis et al.   PHARMACOLOGY & THERAPEUTICS

Allicin inhibits invasion and migration of breast cancer cells through the suppression of VCAM-1: Regulation of association between p65 and ER-α

(2015) Chung Gi Lee et al.   Journal of Functional Foods

Dynamic interplay between breast cancer cells and normal endothelium mediates the expression of matrix macromolecules, proteasome activity and functional properties of endothelial cells

(2014) Ch. Gialeli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

370 AJM300, an oral a4 integrin antagonist, for active ulcerative colitis: a multicenter, randomized, double-blind, placebo-controlled phase 2a study

(2014) Mamoru Watanabe et al.   GASTROINTESTINAL ENDOSCOPY

Activation of VCAM-1 and Its Associated Molecule CD44 Leads to Increased Malignant Potential of Breast Cancer Cells

(2014) Pei-Chen Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The diagnostic, predictive, and prognostic role of serum epithelial cell adhesion molecule (EpCAM) and vascular cell adhesion molecule-1 (VCAM-1) levels in breast cancer

(2014) S. Karabulut et al.   TUMOR BIOLOGY

Lipopolysaccharide induces the interactions of breast cancer and endothelial cells via activated monocytes

(2013) Chong Chen et al.   CANCER LETTERS

Epidermal Growth Factor (EGF)-enhanced Vascular Cell Adhesion Molecule-1 (VCAM-1) Expression Promotes Macrophage and Glioblastoma Cell Interaction and Tumor Cell Invasion

(2013) Yanhua Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways

(2013) Caiyu Lin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Oral treatment with a novel small molecule alpha 4 integrin antagonist, AJM300, prevents the development of experimental colitis in mice

(2013) Toshihiko Sugiura et al.   Journal of Crohns & Colitis

Functional role of endothelial adhesion molecules in the early stages of brain metastasis

(2013) Manuel Sarmiento Soto et al.   NEURO-ONCOLOGY

PI3K  activates integrin  4 1 to establish a metastatic niche in lymph nodes

(2013) B. Garmy-Susini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Pathways: VCAM-1 as a Potential Therapeutic Target in Metastasis

(2012) Q. Chen et al.   CLINICAL CANCER RESEARCH

Molecular MRI enables early and sensitive detection of brain metastases

(2012) S. Serres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment: therapeutic implications

(2011) Klaus Podar et al.   BRITISH JOURNAL OF HAEMATOLOGY

VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors

(2011) Xin Lu et al.   CANCER CELL

Macrophage Binding to Receptor VCAM-1 Transmits Survival Signals in Breast Cancer Cells that Invade the Lungs

(2011) Qing Chen et al.   CANCER CELL

Current management and treatment strategies for breast cancer

(2011) John H. Howard et al.   CURRENT OPINION IN OBSTETRICS & GYNECOLOGY

The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs

(2011) Robert R. Langley et al.   INTERNATIONAL JOURNAL OF CANCER

Preparation andin vitroevaluation of anti-VCAM-1-Fab′-conjugated liposomes for the targeted delivery of the poorly water-soluble drug celecoxib

(2011) Dong Il Kang et al.   JOURNAL OF MICROENCAPSULATION

Organizing the cell cortex: the role of ERM proteins

(2010) Richard G. Fehon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tumor Self-Seeding by Circulating Cancer Cells

(2009) Mi-Young Kim et al.   CELL

S1066 Oral Alpha-4 Integrin Inhibitor (AJM300) in Patients with Active Crohn's Disease — A Randomized, Double-Blind, Placebo-Controlled Trial

(2009) Masakazu Takazoe et al.   GASTROENTEROLOGY

VCAM-1 directed immunoliposomes selectively target tumor vasculature in vivo

(2008) Sara Gosk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Tanshinone I suppresses growth and invasion of human breast cancer cells, MDA-MB-231, through regulation of adhesion molecules

(2008) I. T. Nizamutdinova et al.   CARCINOGENESIS

Anticancer effects of tanshinone I in human non-small cell lung cancer

(2008) C.-Y. Lee et al.   MOLECULAR CANCER THERAPEUTICS

VCAM-1 and VLA-4 Modulate Dendritic Cell IL-12p40 Production in Experimental Visceral Leishmaniasis

(2008) Amanda C. Stanley et al.   PLoS Pathogens

PLGA Nanoparticle−Peptide Conjugate Effectively Targets Intercellular Cell-Adhesion Molecule-1

(2007) Na Zhang et al.   BIOCONJUGATE CHEMISTRY