Bcl-2 family proteins and cancer

Bcl-2 antagonist apogossypol (NSC736630) displays single-agent activity in Bcl-2-transgenic mice and has superior efficacy with less toxicity compared with gossypol (NSC19048)

(2008) S. Kitada et al.   BLOOD

Bcl-2-family proteins and hematologic malignancies: history and future prospects

(2008) J. C. Reed   BLOOD

Critical Role of the Stress Chaperone GRP78/BiP in Tumor Proliferation, Survival, and Tumor Angiogenesis in Transgene-Induced Mammary Tumor Development

(2008) D. Dong et al.   CANCER RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Bcl-B Expression in Human Epithelial and Nonepithelial Malignancies

(2008) M. Krajewska et al.   CLINICAL CANCER RESEARCH

Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas

(2008) Hua-chuan Zheng et al.   HUMAN PATHOLOGY

BI-1 Regulates Endoplasmic Reticulum Ca2+Homeostasis Downstream of Bcl-2 Family Proteins

(2008) Chunyan Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Kinase Cθ Is Required for Autophagy in Response to Stress in the Endoplasmic Reticulum

(2008) Kenjiro Sakaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

(2008) Nika N Danial et al.   NATURE MEDICINE

How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

(2008) Jerry E. Chipuk et al.   TRENDS IN CELL BIOLOGY