A3 Adenosine Receptor Agonist Inhibited Survival of Breast Cancer Stem Cells via GLI-1 and ERK1/2 Pathway

Targeting Cellular Signaling Pathways in Breast Cancer Stem Cells and its Implication for Cancer Treatment

(2016) BRUNO RICARDO BARRETO PIRES et al.   ANTICANCER RESEARCH

Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication

(2016) Samantha Kaufhold et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cancer stem cells

(2016) Jeremy N. Rich   MEDICINE

Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population

(2016) Carmela Ciccarelli et al.   Molecular Cancer

Nanoquinacrine induced apoptosis in cervical cancer stem cells through the inhibition of hedgehog-GLI1 cascade: Role of GLI-1

(2016) Anmada Nayak et al.   Scientific Reports

Overexpression of sonic hedgehog in the triple negative breast cancer: clinicopathological characteristics of high burden breast cancer patients from Bangladesh

(2016) A. S. Noman et al.   Scientific Reports

Targeting Notch, Hedgehog and Wnt pathways in cancer stem cells: clinical update

(2015) Naoko Takebe et al.   Nature Reviews Clinical Oncology

Tumor Twitter: Cellular Communication in the Breast Cancer Stem Cell Niche

(2015) M. D. Brooks et al.   Cancer Discovery

Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy

(2015) A Borah et al.   Oncogenesis

Hedgehog Signaling in the Maintenance of Cancer Stem Cells

(2015) Catherine Cochrane et al.   Cancers

Adenosine A3 Receptor Suppresses Prostate Cancer Metastasis by Inhibiting NADPH Oxidase Activity

(2015) Sarvesh Jajoo et al.   NEOPLASIA

Mitochondrial and caspase pathways are involved in the induction of apoptosis by IB-MECA in ovarian cancer cell lines

(2014) Hamideh Abedi et al.   TUMOR BIOLOGY

Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells

(2014) Maryam Hamzeloo-Moghadam et al.   TUMOR BIOLOGY

Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy

(2014) S Daniele et al.   Cell Death & Disease

Imiquimod directly inhibits Hedgehog signalling by stimulating adenosine receptor/protein kinase A-mediated GLI phosphorylation

(2013) F Wolff et al.   ONCOGENE

The Role of Breast Cancer Stem Cells in Metastasis and Therapeutic Implications

(2011) Marco A. Velasco-Velázquez et al.   AMERICAN JOURNAL OF PATHOLOGY

Induction of apoptosis by type Iβ protein kinase G in the human breast cancer cell lines MCF-7 and MDA-MB-468

(2011) Faranak Fallahian et al.   CELL BIOCHEMISTRY AND FUNCTION

Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway

(2011) Mahmoud Aghaei et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3

(2011) Mahmoud Aghaei et al.   PROSTATE

Activation of Akt and MAPK pathways enhances the tumorigenicity of CD133+ primary colon cancer cells

(2010) Y. K. Wang et al.   CARCINOGENESIS

Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells

(2010) Y. Li et al.   CLINICAL CANCER RESEARCH

Review: Targeting the Hedgehog pathway in cancer

(2010) Sachin Gupta et al.   Therapeutic Advances in Medical Oncology

Development of Cell Cycle Inhibitors for Cancer Therapy

(2009) Gary K. Schwartz et al.   Current Oncology

Radiation responses of cancer stem cells

(2009) Erina Vlashi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cancer stem cells: Cell culture, markers, and targets for new therapies

(2009) Candace A. Gilbert et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Gli1 inhibition induces cell-cycle arrest and enhanced apoptosis in brain glioma cell lines

(2009) Ke Wang et al.   JOURNAL OF NEURO-ONCOLOGY

Inhibition of cell proliferation through cell cycle arrest and apoptosis by thio-Cl-IB-MECA, a novel A3 adenosine receptor agonist, in human lung cancer cells

(2008) Sun-Jack Kim et al.   CANCER LETTERS

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT