Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection

Dual RNA-seq unveils noncoding RNA functions in host–pathogen interactions

(2016) Alexander J. Westermann et al.   NATURE

Targeting Staphylococcus aureus Toxins: A Potential form of Anti-Virulence Therapy

(2016) Cin Kong et al.   Toxins

The co-transcriptome of uropathogenicEscherichia coli-infected mouse macrophages reveals new insights into host-pathogen interactions

(2015) Charalampos Harris Mavromatis et al.   CELLULAR MICROBIOLOGY

Serum Lipoproteins Are Critical for Pulmonary Innate Defense againstStaphylococcus aureusQuorum Sensing

(2015) Brett C. Manifold-Wheeler et al.   JOURNAL OF IMMUNOLOGY

Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk

(2015) B. Baddal et al.   mBio

Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling

(2015) Jianfeng Wang et al.   Scientific Reports

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Where does a Staphylococcus aureus vaccine stand?

(2014) V.G. Fowler et al.   CLINICAL MICROBIOLOGY AND INFECTION

Multi-drug-resistant Staphylococcus aureus and future chemotherapy

(2014) K. Hiramatsu et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

High-Resolution Transcriptomic Analysis of the Adaptive Response of Staphylococcus aureus during Acute and Chronic Phases of Osteomyelitis

(2014) Anna K. Szafranska et al.   mBio

Identification of Anti-virulence Compounds That Disrupt Quorum-Sensing Regulated Acute and Persistent Pathogenicity

(2014) Melissa Starkey et al.   PLoS Pathogens

Assessment of an Anti-Alpha-Toxin Monoclonal Antibody for Prevention and Treatment of Staphylococcus aureus-Induced Pneumonia

(2013) L. Hua et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Induction kinetics of the Staphylococcus aureus cell wall stress stimulon in response to different cell wall active antibiotics

(2013) Vanina Dengler et al.   BMC MICROBIOLOGY

A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis

(2013) James E. Cassat et al.   Cell Host & Microbe

Staphylococcus aureus toxins

(2013) Michael Otto   CURRENT OPINION IN MICROBIOLOGY

Staphylococcal Proteases Aid in Evasion of the Human Complement System

(2013) Monika Jusko et al.   Journal of Innate Immunity

Simultaneous Transcriptional Profiling of Bacteria and Their Host Cells

(2013) Michael S. Humphrys et al.   PLoS One

Targeting the bacteria–host interface

(2013) Anne Marie Krachler et al.   Virulence

Phagocytosis Escape by a Staphylococcus aureus Protein That Connects Complement and Coagulation Proteins at the Bacterial Surface

(2013) Ya-Ping Ko et al.   PLoS Pathogens

Arginase: The Emerging Therapeutic Target for Vascular Oxidative Stress and Inflammation

(2013) Zhihong Yang et al.   Frontiers in Immunology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Intravital two-photon microscopy of host-pathogen interactions in a mouse model ofStaphylococcus aureusskin abscess formation

(2012) Jan Liese et al.   CELLULAR MICROBIOLOGY

Identification of Anti-Alpha Toxin Monoclonal Antibodies That Reduce the Severity of Staphylococcus aureus Dermonecrosis and Exhibit a Correlation between Affinity and Potency

(2012) C. Tkaczyk et al.   Clinical and Vaccine Immunology

Beyond conventional antibiotics for the future treatment of methicillin-resistantStaphylococcus aureusinfections: two novel alternatives

(2012) Deirdre Fitzgerald-Hughes et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Dual RNA-seq of pathogen and host

(2012) Alexander J. Westermann et al.   NATURE REVIEWS MICROBIOLOGY

Staphylococcus aureus Hemolysins, bi-component Leukocidins, and Cytolytic Peptides: A Redundant Arsenal of Membrane-Damaging Virulence Factors?

(2012) François Vandenesch et al.   Frontiers in Cellular and Infection Microbiology

Extracellular proteases are key mediators ofStaphylococcus aureusvirulence via the global modulation of virulence-determinant stability

(2012) Stacey L. Kolar et al.   MicrobiologyOpen

Coordinated Regulation by AgrA, SarA, and SarR To Control agr Expression in Staphylococcus aureus

(2011) D. Reyes et al.   JOURNAL OF BACTERIOLOGY

Staphylococcus aureus Metalloprotease Aureolysin Cleaves Complement C3 To Mediate Immune Evasion

(2011) A. J. Laarman et al.   JOURNAL OF IMMUNOLOGY

Broad-spectrum antimicrobial peptide resistance by MprF-mediated aminoacylation and flipping of phospholipids

(2011) Christoph M. Ernst et al.   MOLECULAR MICROBIOLOGY

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

(2011) Ichiro Inoshima et al.   NATURE MEDICINE

Antivirulence drugs to target bacterial secretion systems

(2010) Christian Baron   CURRENT OPINION IN MICROBIOLOGY

Staphylococcus aureus SH1000 and 8325-4: comparative genome sequences of key laboratory strains in staphylococcal research

(2010) A.J. O’Neill   LETTERS IN APPLIED MICROBIOLOGY

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

Two Genes on A/J Chromosome 18 Are Associated with Susceptibility to Staphylococcus aureus Infection by Combined Microarray and QTL Analyses

(2010) Sun-Hee Ahn et al.   PLoS Pathogens

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Staphylococcal cysteine protease staphopain B (SspB) induces rapid engulfment of human neutrophils and monocytes by macrophages

(2009) Jan Smagur et al.   BIOLOGICAL CHEMISTRY

Effect of a glucose impulse on the CcpA regulon in Staphylococcus aureus

(2009) Kati Seidl et al.   BMC MICROBIOLOGY

Immunological Mechanisms Underlying the Genetic Predisposition to Severe Staphylococcus aureus Infection in the Mouse Model

(2008) Maren von Köckritz-Blickwede et al.   AMERICAN JOURNAL OF PATHOLOGY

RNAIII-Inhibiting Peptide Enhances Healing of Wounds Infected with Methicillin-Resistant Staphylococcus aureus

(2008) O. Simonetti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biology of HIF-1α

(2008) A Weidemann et al.   CELL DEATH AND DIFFERENTIATION

Apolipoprotein B Is an Innate Barrier against Invasive Staphylococcus aureus Infection

(2008) M. Michal Peterson et al.   Cell Host & Microbe

Maximal transcription ofaur(aureolysin) andsspA(serine protease) inStaphylococcus aureusrequires staphylococcal accessory regulator R (sarR) activity

(2008) Erik Gustafsson et al.   FEMS MICROBIOLOGY LETTERS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Targeting QseC Signaling and Virulence for Antibiotic Development

(2008) D. A. Rasko et al.   SCIENCE

The Epidemic of Antibiotic-Resistant Infections: A Call to Action for the Medical Community from the Infectious Diseases Society of America

(2007) B. Spellberg et al.   CLINICAL INFECTIOUS DISEASES

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY