Hierarchical tissue organization as a general mechanism to limit the accumulation of somatic mutations
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Title
Hierarchical tissue organization as a general mechanism to limit the accumulation of somatic mutations
Authors
Keywords
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Journal
Nature Communications
Volume 8, Issue -, Pages 14545
Publisher
Springer Nature
Online
2017-02-23
DOI
10.1038/ncomms14545
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- (2015) C. Tomasetti et al. SCIENCE
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