Interpreting the Dependence of Mutation Rates on Age and Time

Lagging-strand replication shapes the mutational landscape of the genome

(2015) Martin A. M. Reijns et al.   NATURE

Genome-wide patterns and properties of de novo mutations in humans

(2015) Laurent C Francioli et al.   NATURE GENETICS

Clock-like mutational processes in human somatic cells

(2015) Ludmil B Alexandrov et al.   NATURE GENETICS

Somatic mutation in single human neurons tracks developmental and transcriptional history

(2015) M. A. Lodato et al.   SCIENCE

Variation in cancer risk among tissues can be explained by the number of stem cell divisions

(2015) C. Tomasetti et al.   SCIENCE

Examining Variation in Recombination Levels in the Human Female: A Test of the Production-Line Hypothesis

(2014) Ross Rowsey et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Determinants of Mutation Rate Variation in the Human Germline

(2014) Laure Ségurel et al.   Annual Review of Genomics and Human Genetics

A framework for the interpretation of de novo mutation in human disease

(2014) Kaitlin E Samocha et al.   NATURE GENETICS

Pattern of Mutation Rates in the Germline of Drosophila melanogaster Males from a Large-Scale Mutation Screening Experiment

(2014) Jian-Jun Gao et al.   G3-Genes Genomes Genetics

The Human Mutation Rate Is Increasing, Even As It Slows

(2013) Gregg W.C. Thomas et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Half or more of the somatic mutations in cancers of self-renewing tissues originate prior to tumor initiation

(2013) C. Tomasetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rate of de novo mutations and the importance of father’s age to disease risk

(2012) Augustine Kong et al.   NATURE

16. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010

(2011) D M Parkin et al.   BRITISH JOURNAL OF CANCER

Highly variable recessive lethal or nearly lethal mutation rates during germ-line development of male Drosophila melanogaster

(2011) J.-J. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational Heterogeneity in Human Cancers: Origin and Consequences

(2009) Jesse J. Salk et al.   Annual Review of Pathology-Mechanisms of Disease

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

Spermatogonial stem cells in higher primates: are there differences from those in rodents?

(2009) Brian P Hermann et al.   REPRODUCTION

Hominin life history: reconstruction and evolution

(2008) Shannen L. Robson et al.   JOURNAL OF ANATOMY