A deterministic model for the occurrence and dynamics of multiple mutations in hierarchically organized tissues

Developmental timing of mutations revealed by whole-genome sequencing of twins with acute lymphoblastic leukemia

(2013) Y. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

(2012) John S. Welch et al.   CELL

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

The telomere syndromes

(2012) Mary Armanios et al.   NATURE REVIEWS GENETICS

Clonal Architecture of Secondary Acute Myeloid Leukemia

(2012) Matthew J. Walter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular aging leads to functional heterogeneity of hematopoietic stem cells: a modeling perspective

(2011) Ingmar Glauche et al.   AGING CELL

Explaining the in vitro and in vivo differences in leukemia therapy

(2011) Tom Lenaerts et al.   CELL CYCLE

Evolutionary dynamics of feedback escape and the development of stem-cell-driven cancers

(2011) I. A. Rodriguez-Brenes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolving homeostatic tissue using genetic algorithms

(2011) Philip Gerlee et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Dynamics of Mutant Cells in Hierarchical Organized Tissues

(2011) Benjamin Werner et al.   PLoS Computational Biology

Cellular barcoding tool for clonal analysis in the hematopoietic system

(2010) A. Gerrits et al.   BLOOD

Waiting Time Models of Cancer Progression

(2010) MORITZ GERSTUNG et al.   Mathematical Population Studies

Nilotinib versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia

(2010) Giuseppe Saglio et al.   NEW ENGLAND JOURNAL OF MEDICINE

Accumulation of driver and passenger mutations during tumor progression

(2010) I. Bozic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia

(2009) F. C. Guibal et al.   BLOOD

The stem cells of small intestinal crypts: where are they?

(2009) C. S. Potten et al.   CELL PROLIFERATION

Tyrosine kinase inhibitor therapy can cure chronic myeloid leukemia without hitting leukemic stem cells

(2009) T. Lenaerts et al.   HAEMATOLOGICA

A comprehensive catalogue of somatic mutations from a human cancer genome

(2009) Erin D. Pleasance et al.   NATURE

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Skin stem cells: rising to the surface

(2008) Elaine Fuchs   JOURNAL OF CELL BIOLOGY

Comparative lesion sequencing provides insights into tumor evolution

(2008) S. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Initiating and Cancer-Propagating Cells in TEL-AML1-Associated Childhood Leukemia

(2008) D. Hong et al.   SCIENCE

Modeling of Asymmetric Cell Division in Hematopoietic Stem Cells—Regulation of Self-Renewal Is Essential for Efficient Repopulation

(2008) Anna Marciniak-Czochra et al.   STEM CELLS AND DEVELOPMENT