Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions

Identification and Structure-Activity Relationship Studies of Small-Molecule Inhibitors of the Methyllysine Reader Protein Spindlin1

(2016) Dina Robaa et al.   ChemMedChem

Reshaping the Chromatin and Epigenetic Landscapes with Quantitative Mass Spectrometry

(2016) Michael P. Washburn et al.   MOLECULAR & CELLULAR PROTEOMICS

Chromatin condensation and recruitment of PHD finger proteins to histone H3K4me3 are mutually exclusive

(2016) Jovylyn Gatchalian et al.   NUCLEIC ACIDS RESEARCH

Identification of a small-molecule ligand of the epigenetic reader protein Spindlin1 via a versatile screening platform

(2016) Tobias Wagner et al.   NUCLEIC ACIDS RESEARCH

A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks

(2016) Dinshaw J. Patel   Cold Spring Harbor Perspectives in Biology

Reader domain specificity and lysine demethylase-4 family function

(2016) Zhangli Su et al.   Nature Communications

Histone H4 Lysine 20 (H4K20) Methylation, Expanding the Signaling Potential of the Proteome One Methyl Moiety at a Time

(2015) Rick van Nuland et al.   MOLECULAR & CELLULAR PROTEOMICS

The histone code reader SPIN1 controls RET signaling in liposarcoma

(2015) Henriette Franz et al.   Oncotarget

Interpreting the language of histone and DNA modifications

(2014) Scott B. Rothbart et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1

(2014) X. Su et al.   GENES & DEVELOPMENT

ChIP-less analysis of chromatin states

(2014) Zhangli Su et al.   Epigenetics & Chromatin

Concerted Activities of Distinct H4K20 Methyltransferases at DNA Double-Strand Breaks Regulate 53BP1 Nucleation and NHEJ-Directed Repair

(2014) Creighton T. Tuzon et al.   Cell Reports

Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis

(2014) Romeo Papazyan et al.   eLife

Tudor domains of the PRC2 components PHF1 and PHF19 selectively bind to histone H3K36me3

(2012) Su Qin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins

(2012) Melanie A. Adams-Cioaba et al.   FEBS LETTERS

SPINDLIN1 Promotes Cancer Cell Proliferation through Activation of WNT/TCF-4 Signaling

(2012) J.-X. Wang et al.   MOLECULAR CANCER RESEARCH

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

(2012) Joshua C. Black et al.   MOLECULAR CELL

An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting

(2012) Ling Cai et al.   MOLECULAR CELL

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

(2012) Alex J. Kuo et al.   NATURE

Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance

(2012) Valentina Migliori et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity

(2012) Cecilia Ballaré et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

(2012) Scott B Rothbart et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1

(2012) Catherine A Musselman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Perceiving the epigenetic landscape through histone readers

(2012) Catherine A Musselman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1

(2012) N. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alterations of global histone H4K20 methylation during prostate carcinogenesis

(2012) Turang E Behbahani et al.   BMC Urology

Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails

(2011) Ina Bock et al.   BMC BIOCHEMISTRY

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Chromatin higher-order structures and gene regulation

(2011) Guohong Li et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation

(2011) Chuanbing Bian et al.   EMBO JOURNAL

Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes

(2011) Weixiang Wang et al.   EMBO REPORTS

Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein

(2011) Nataliya Nady et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights for MPP8 Chromodomain Interaction with Histone H3 Lysine 9: Potential Effect of Phosphorylation on Methyl-Lysine Binding

(2011) Yanqi Chang et al.   JOURNAL OF MOLECULAR BIOLOGY

OPERating ON Chromatin, a Colorful Language where Context Matters

(2011) Kathryn E. Gardner et al.   JOURNAL OF MOLECULAR BIOLOGY

Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation

(2011) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Keeping it in the family: diverse histone recognition by conserved structural folds

(2010) Kyoko L. Yap et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Influence of Combinatorial Histone Modifications on Antibody and Effector Protein Recognition

(2010) Stephen M. Fuchs et al.   CURRENT BIOLOGY

Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion

(2010) Kenji Kokura et al.   EMBO JOURNAL

Recognition and Specificity Determinants of the Human Cbx Chromodomains

(2010) Lilia Kaustov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic Identification of Methyllysine-Driven Interactions for Histone and Nonhistone Targets

(2010) Huadong Liu et al.   JOURNAL OF PROTEOME RESEARCH

TDRD3 Is an Effector Molecule for Arginine-Methylated Histone Marks

(2010) Yanzhong Yang et al.   MOLECULAR CELL

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members

(2009) V. V. Vagin et al.   GENES & DEVELOPMENT

Genomic distribution of CHD7 on chromatin tracks H3K4 methylation patterns

(2009) M. P. Schnetz et al.   GENOME RESEARCH

Multimerization and H3K9me3 Binding Are Required for CDYL1b Heterochromatin Association

(2009) Henriette Franz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenome Microarray Platform for Proteome-Wide Dissection of Chromatin-Signaling Networks

(2009) Dennis J. Bua et al.   PLoS One

Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi

(2009) C. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crosstalk among Histone Modifications

(2008) Tamaki Suganuma et al.   CELL

Loss of Histone H4K20 Trimethylation Occurs in Preneoplasia and Influences Prognosis of Non-Small Cell Lung Cancer

(2008) A. Van Den Broeck et al.   CLINICAL CANCER RESEARCH

Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis

(2008) Hongfeng Yuan et al.   GENE

Specificity of the Chromodomain Y Chromosome Family of Chromodomains for Lysine-methylated ARK(S/T) Motifs

(2008) Wolfgang Fischle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Overexpression of spindlin1 induces metaphase arrest and chromosomal instability

(2008) Peng Zhang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

(2008) Robert E Collins et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY