Early Anti-inflammatory and Pro-angiogenic Myocardial Effects of Intravenous Serelaxin Infusion for 72 H in an Experimental Rat Model of Acute Myocardial Infarction
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Title
Early Anti-inflammatory and Pro-angiogenic Myocardial Effects of Intravenous Serelaxin Infusion for 72 H in an Experimental Rat Model of Acute Myocardial Infarction
Authors
Keywords
Myocardial infarction, Left ventricular systolic dysfunction, Serelaxin, Remodeling, Fibrosis
Journal
Journal of Cardiovascular Translational Research
Volume 10, Issue 5-6, Pages 460-469
Publisher
Springer Nature
Online
2017-07-17
DOI
10.1007/s12265-017-9761-1
References
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Note: Only part of the references are listed.- Serelaxin in addition to standard therapy in acute heart failure: rationale and design of the RELAX-AHF-2 study
- (2017) John R. Teerlink et al. EUROPEAN JOURNAL OF HEART FAILURE
- Galectin-3 and post-myocardial infarction cardiac remodeling
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- Relaxin’ the Heart
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- Acute treatment with relaxin protects the kidney against ischaemia/reperfusion injury
- (2013) Massimo Collino et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Relaxin Family Peptides and Their Receptors
- (2013) R. A. D. Bathgate et al. PHYSIOLOGICAL REVIEWS
- Up-Regulating Relaxin Expression by G-Quadruplex Interactive Ligand to Achieve Antifibrotic Action
- (2012) Hui-Ping Gu et al. ENDOCRINOLOGY
- Identification of Key Residues Essential for the Structural Fold and Receptor Selectivity within the A-chain of Human Gene-2 (H2) Relaxin
- (2012) Linda J. Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial
- (2012) John R Teerlink et al. LANCET
- Relaxin remodels fibrotic healing following myocardial infarction
- (2011) Chrishan S Samuel et al. LABORATORY INVESTIGATION
- Interleukin-33 Prevents Apoptosis and Improves Survival After Experimental Myocardial Infarction Through ST2 Signaling
- (2009) Kenjiro Seki et al. Circulation-Heart Failure
- Relaxin is a candidate drug for lung preservation: Relaxin-induced protection of rat lungs from ischemia-reperfusion injury
- (2009) Konstantin Alexiou et al. JOURNAL OF HEART AND LUNG TRANSPLANTATION
- Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study
- (2009) John R Teerlink et al. LANCET
- Functional and histopathological improvement of the post-infarcted rat heart upon myoblast cell grafting and relaxin therapy
- (2008) Massimo Bonacchi et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- The IL-33/ST2 pathway: therapeutic target and novel biomarker
- (2008) Rahul Kakkar et al. NATURE REVIEWS DRUG DISCOVERY
- Adenovirus-mediated delivery of relaxin reverses cardiac fibrosis
- (2007) R.A.D. Bathgate et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Relaxin induces mast cell inhibition and reduces ventricular arrhythmias in a swine model of acute myocardial infarction
- (2007) Silvia Nistri et al. PHARMACOLOGICAL RESEARCH
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