Betulin exhibits anti-inflammatory activity in LPS-stimulated macrophages and endotoxin-shocked mice through an AMPK/AKT/Nrf2-dependent mechanism

PHLPP2 down regulation influences nuclear Nrf2 stability via Akt-1/Gsk3β/Fyn kinase axis in acetaminophen induced oxidative renal toxicity: Protection accorded by morin

(2016) Alpana Mathur et al.   FOOD AND CHEMICAL TOXICOLOGY

Betulin attenuates lung and liver injuries in sepsis

(2016) Hongyu Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Role of reactive oxygen species-mediated MAPK and NF-κB activation inpolygonatum cyrtonemalectin-induced apoptosis and autophagy in human lung adenocarcinoma A549 cells

(2016) Tao Liu et al.   JOURNAL OF BIOCHEMISTRY

Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats

(2016) Chunhua Ma et al.   NEUROTOXICOLOGY

Betulin alleviated ethanol-induced alcoholic liver injury via SIRT1/AMPK signaling pathway

(2016) Ting Bai et al.   PHARMACOLOGICAL RESEARCH

TrxR1 as a Potent Regulator of the Nrf2-Keap1 Response System

(2015) Marcus Cebula et al.   ANTIOXIDANTS & REDOX SIGNALING

Salidroside ameliorates insulin resistance through activation of a mitochondria-associated AMPK/PI3K/Akt/GSK3β pathway

(2015) Tao Zheng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Betulin suppresses S. aureus -induced mammary gland inflammatory injury by regulating PPAR-γ in mice

(2015) Meng-yao Guo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inflammation-induced oxidative stress in breast cancer patients

(2015) Aline Tengan Roque et al.   MEDICAL ONCOLOGY

The Cytoprotective Effect of Hyperoside against Oxidative Stress Is Mediated by the Nrf2-ARE Signaling Pathway through GSK-3β Inactivation

(2015) Hai-Yan Xing et al.   PLoS One

AMPK: A cellular metabolic and redox sensor. A minireview

(2014) Najeeb Shirwany   Frontiers in Bioscience-Landmark

Upregulation of heme oxygenase-1 expression by dehydrodiconiferyl alcohol (DHCA) through the AMPK–Nrf2 dependent pathway

(2014) Junghun Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nuclear Factor Erythroid 2 - Related Factor 2 Signaling in Parkinson Disease: A Promising Multi Therapeutic Target Against Oxidative Stress, Neuroinflammation and Cell Death

(2013) Hemant Kumar et al.   CNS & Neurological Disorders-Drug Targets

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

(2013) Hemant Kumar et al.   NATURAL PRODUCT REPORTS

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

AMP-activated protein kinase: new regulation, new roles?

(2012) David Carling et al.   BIOCHEMICAL JOURNAL

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Nrf2 in Suppressing LPS-Induced Inflammation in Mouse Peritoneal Macrophages by Polyunsaturated Fatty Acids Docosahexaenoic Acid and Eicosapentaenoic Acid

(2010) Hu Wang et al.   MOLECULAR PHARMACEUTICS

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

AMPK-mediated GSK3β inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress

(2009) Song Hwa Choi et al.   BIOCHEMICAL PHARMACOLOGY

Nrf2 signaling and cell survival

(2009) Suryakant K. Niture et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

AMP-activated Protein Kinase Activation Increases Phosphorylation of Glycogen Synthase Kinase 3β and Thereby Reduces cAMP-responsive Element Transcriptional Activity and Phosphoenolpyruvate Carboxykinase C Gene Expression in the Liver

(2008) Nanao Horike et al.   JOURNAL OF BIOLOGICAL CHEMISTRY