Role of reactive oxygen species-mediated MAPK and NF-κB activation inpolygonatum cyrtonemalectin-induced apoptosis and autophagy in human lung adenocarcinoma A549 cells

Polygonatum odoratum lectin induces apoptosis and autophagy by regulation of microRNA-1290 and microRNA-15a-3p in human lung adenocarcinoma A549 cells

(2016) Lei Wu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells

(2015) Lei Gao et al.   APOPTOSIS

Molecular Switch Role of Akt in Polygonatum odoratum Lectin-Induced Apoptosis and Autophagy in Human Non-Small Cell Lung Cancer A549 Cells

(2014) Chunyang Li et al.   PLoS One

Autophagy modulation as a target for anticancer drug discovery

(2013) Xin Li et al.   ACTA PHARMACOLOGICA SINICA

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion

(2013) Neel Sengupta et al.   Molecular Cancer

Anti-tumor and anti-viral activities of Galanthus nivalis agglutinin (GNA)-related lectins

(2012) Lei Wu et al.   GLYCOCONJUGATE JOURNAL

Hirsutanol A Induces Apoptosis and Autophagy via Reactive Oxygen Species Accumulation in Breast Cancer MCF-7 Cells

(2012) Fen Yang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Apoptosis-inducing effect and structural basis of Polygonatum cyrtonema lectin and chemical modification properties on its mannose-binding sites

(2011) Bo Liu et al.   BMB Reports

Autophagic pathways as new targets for cancer drug development

(2010) Bo Liu et al.   ACTA PHARMACOLOGICA SINICA

Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis and autophagy via blocking Ras–Raf and PI3K–Akt signaling pathways

(2010) Bo Liu et al.   BIOCHIMIE

Evolutionary history and stress regulation of the lectin superfamily in higher plants

(2010) Shu-Ye Jiang et al.   BMC EVOLUTIONARY BIOLOGY

Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis via a caspase-dependent pathway as compared to Ophiopogon japonicus lectin

(2010) Zi-ting Zhang et al.   PHYTOMEDICINE

Induction of apoptosis by Polygonatum odoratum lectin and its molecular mechanisms in murine fibrosarcoma L929 cells

(2009) Bo Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Plant lectins: Potential antineoplastic drugs from bench to clinic

(2009) Bo Liu et al.   CANCER LETTERS

Bioinformatics analyses of the mannose-binding lectins from Polygonatum cyrtonema, Ophiopogon japonicus and Liparis noversa with antiproliferative and apoptosis-inducing activities

(2009) Bo Liu et al.   PHYTOMEDICINE

ERK and JNK mediate TNFα-induced p53 activation in apoptotic and autophagic L929 cell death

(2008) Yan Cheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS–p38–p53 pathway

(2008) Bo Liu et al.   CANCER LETTERS

Mistletoe Lectins: Carbohydrate-Specific Apoptosis Inducers and Immunomodulators

(2008) Daniel Hoessli et al.   CURRENT ORGANIC CHEMISTRY