Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis

Heme oxygenase 1 improves glucoses metabolism and kidney histological alterations in diabetic rats

(2013) Ellen ON Ptilovanciv et al.   Diabetology & Metabolic Syndrome

Thrombomodulin Links Coagulation to Inflammation and Immunity

(2012) John Morser   CURRENT DRUG TARGETS

The lectin-like domain of thrombomodulin ameliorates diabetic glomerulopathy via complement inhibition

(2012) Ilya Vinnikov et al.   THROMBOSIS AND HAEMOSTASIS

Antroquinonol differentially modulates T cell activity and reduces interleukin-18 production, but enhances Nrf2 activation, in murine accelerated severe lupus nephritis

(2011) Pei-Yi Tsai et al.   ARTHRITIS AND RHEUMATISM

The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis Y antigen

(2011) C.-H. Kuo et al.   BLOOD

Kidney-targeting Smad7 gene transfer inhibits renal TGF-β/MAD homologue (SMAD) and nuclear factor κB (NF-κB) signalling pathways, and improves diabetic nephropathy in mice

(2011) S. M. Ka et al.   DIABETOLOGIA

Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation

(2011) Pei-Yi Tsai et al.   FREE RADICAL BIOLOGY AND MEDICINE

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

(2011) Bolormaa Vandanmagsar et al.   NATURE MEDICINE

Thrombomodulin and its role in inflammation

(2011) Edward M. Conway   Seminars in Immunopathology

Glycemic Control and Complications in Type 2 Diabetes Mellitus

(2010) Mark Stolar   AMERICAN JOURNAL OF MEDICINE

Relationship between Oxidative Stress and Inflammatory Cytokines in Diabetic Nephropathy

(2010) Ahmed A. Elmarakby et al.   Cardiovascular Therapeutics

Oxidative Stress in Diabetic Nephropathy

(2010) N. Kashihara et al.   CURRENT MEDICINAL CHEMISTRY

Thrombomodulin is Upregulated in Cardiomyocytes During Cardiac Hypertrophy and Prevents the Progression of Contractile Dysfunction

(2010) Yi-Heng Li et al.   JOURNAL OF CARDIAC FAILURE

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

(2010) Seth L Masters et al.   NATURE IMMUNOLOGY

Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response

(2008) C.-S. Shi et al.   BLOOD

Establishment of Conditionally Immortalized Mouse Glomerular Parietal Epithelial Cells in Culture

(2008) T. Ohse et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Overexpression of Heme Oxygenase-1 Protects Dopaminergic Neurons against 1-Methyl-4-Phenylpyridinium-Induced Neurotoxicity

(2008) S.-Y. Hung et al.   MOLECULAR PHARMACOLOGY

Activated Protein C and Diabetic Nephropathy

(2008) Richard E. Gilbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG

(2007) Hye-Kyung Na et al.   FOOD AND CHEMICAL TOXICOLOGY