Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death

Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer

(2016) Weimin Wang et al.   CELL

Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism

(2015) Helena Joyce et al.   Expert Opinion on Drug Metabolism & Toxicology

Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death

(2015) Elin Naderi et al.   Molecular Cancer

Anthracyclines induce double-strand DNA breaks at active gene promoters

(2015) Fan Yang et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer

(2015) Matthew K.H. Hong et al.   Nature Communications

Differential expression of the multidrug resistance 1 (MDR1) protein in prostate cancer cells is independent from anticancer drug treatment and Y box binding protein 1 (YB-1) activity

(2014) Madeleine Saupe et al.   WORLD JOURNAL OF UROLOGY

Mechanisms and insights into drug resistance in cancer

(2013) Hiba Zahreddine et al.   Frontiers in Pharmacology

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

(2012) Wan Zhang et al.   NATURE CELL BIOLOGY

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

(2012) Zheng Sun et al.   NATURE MEDICINE

Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells

(2012) P Kharaziha et al.   Cell Death & Disease

Gamma-glutamyl compounds: Substrate specificity of gamma-glutamyl transpeptidase enzymes

(2011) Stephanie Wickham et al.   ANALYTICAL BIOCHEMISTRY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

(2011) Stephanos Pavlides et al.   CELL CYCLE

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect

(2011) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

The autophagic tumor stroma model of cancer

(2010) Stephanos Pavlides et al.   CELL CYCLE

Hallmarks of cancer: Interactions with the tumor stroma

(2010) Kristian Pietras et al.   EXPERIMENTAL CELL RESEARCH

Stromal PDGFRβ Expression in Prostate Tumors and Non-Malignant Prostate Tissue Predicts Prostate Cancer Survival

(2010) Christina Hägglöf et al.   PLoS One

Activation of cAMP signaling inhibits DNA damage-induced apoptosis in BCP-ALL cells through abrogation of p53 accumulation

(2009) E. H. Naderi et al.   BLOOD

Human Prostate Fibroblasts Induce Growth and Confer Castration Resistance and Metastatic Potential in LNCaP Cells

(2009) George N. Thalmann et al.   EUROPEAN UROLOGY

30 years and a long way into p53 research

(2009) Pierre Hainaut et al.   LANCET ONCOLOGY

KLF6 and TP53 mutations are a rare event in prostate cancer: distinguishing between Taq polymerase artifacts and true mutations

(2008) Laia Agell et al.   MODERN PATHOLOGY

Fluorescence intensity and lifetime imaging of free and micellar-encapsulated doxorubicin in living cells

(2008) Xiaowen Dai et al.   Nanomedicine-Nanotechnology Biology and Medicine

No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas

(2008) Wen Qiu et al.   NATURE GENETICS