The autophagic tumor stroma model of cancer

Autophagy and amyotrophic lateral sclerosis: The multiple roles of lithium

(2014) Francesco Fornai et al.   Autophagy

Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer

(2014) Allen S. Ho et al.   Translational Oncology

Clinicopathological Significance of microRNA-31, -143 and -145 Expression in Colorectal Cancer

(2013) Chao-Jie Wang et al.   DISEASE MARKERS

Towards a new “stromal-based” classification system for human breast cancer prognosis and therapy

(2011) Agnieszka K. Witkiewicz et al.   CELL CYCLE

An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease spread and epithelial Akt activation

(2011) Dolores Di Vizio et al.   CELL CYCLE

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

(2011) Stephanos Pavlides et al.   CELL CYCLE

Epidemiological aspects of neoplasms in diabetes

(2010) Antonio Nicolucci   ACTA DIABETOLOGICA

A genomic screen for yeast mutants defective in mitophagy

(2010) Tomotake Kanki et al.   Autophagy

The Anti-apoptotic Action of 5-Hydroxyindole: Protection of Mitochondrial Integrity

(2010) Sung Jin Bae et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 down-regulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy

(2010) Isabelle Mercier et al.   CANCER BIOLOGY & THERAPY

Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer

(2010) Agnieszka K. Witkiewicz et al.   CANCER BIOLOGY & THERAPY

Stromal CD10 and SPARC expression in ductal carcinoma in situ (DCIS) patients predicts disease recurrence

(2010) Agnieszka K. Witkiewicz et al.   CANCER BIOLOGY & THERAPY

miR-31 Ablates Expression of the HIF Regulatory Factor FIH to Activate the HIF Pathway in Head and Neck Carcinoma

(2010) C.-J. Liu et al.   CANCER RESEARCH

Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: Evidence for stromal-epithelial metabolic coupling

(2010) Gemma Migneco et al.   CELL CYCLE

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution

(2010) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the “reverse Warburg effect”: A transcriptional informatics analysis with validation

(2010) Stephanos Pavlides et al.   CELL CYCLE

Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: Implications for breast cancer and DCIS therapy with autophagy inhibitors

(2010) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

MicroRNA-210: A unique and pleiotropic hypoxamir

(2010) Stephen Y. Chan et al.   CELL CYCLE

Metabolomic analysis of serum by (1) H NMR spectroscopy in amyotrophic lateral sclerosis

(2010) Alok Kumar et al.   CLINICA CHIMICA ACTA

Review article: Asymmetric dimethylarginine as a mediator of vascular dysfunction and a marker of cardiovascular disease and mortality: an intriguing interaction with diabetes mellitus

(2010) Maike Anderssohn et al.   Diabetes & Vascular Disease Research

Unknown

(2010) Anita Ost et al.   MOLECULAR MEDICINE

Increase of microRNAmiR-31level in plasma could be a potential marker of oral cancer

(2010) C-J Liu et al.   ORAL DISEASES

p38 MAPK/MK2-mediated induction of miR-34c following DNA damage prevents Myc-dependent DNA replication

(2010) I. G. Cannell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caveolin-1−/− Null Mammary Stromal Fibroblasts Share Characteristics with Human Breast Cancer-Associated Fibroblasts

(2009) Federica Sotgia et al.   AMERICAN JOURNAL OF PATHOLOGY

Quis Custodiet Ipsos Custodies

(2009) Cyrus M. Ghajar et al.   AMERICAN JOURNAL OF PATHOLOGY

Stromal Cell Expression of Caveolin-1 Predicts Outcome in Breast Cancer

(2009) Erica K. Sloan et al.   AMERICAN JOURNAL OF PATHOLOGY

An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers

(2009) Agnieszka K. Witkiewicz et al.   AMERICAN JOURNAL OF PATHOLOGY

The paradox of autophagy and its implication in cancer etiology and therapy

(2009) Avital Eisenberg-Lerner et al.   APOPTOSIS

Pathway analysis of senescence-associated miRNA targets reveals common processes to different senescence induction mechanisms

(2009) Kyle Lafferty-Whyte et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hypoxia-induced autophagy: cell death or cell survival?

(2009) Nathalie M Mazure et al.   CURRENT OPINION IN CELL BIOLOGY

Role of asymmetric-dimethyl-l-arginine (ADMA) and nitrite/nitrate (NOx) in the pathogenesis of oxidative stress in female subjects with uncomplicated type 1 diabetes mellitus

(2009) Dario Pitocco et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Glutathione Participates in the Regulation of Mitophagy in Yeast

(2009) Maika Deffieu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

A Genomic Screen for Yeast Mutants Defective in Selective Mitochondria Autophagy

(2009) Tomotake Kanki et al.   MOLECULAR BIOLOGY OF THE CELL

Cellular ADMA: Regulation and action

(2009) Tom Teerlink et al.   PHARMACOLOGICAL RESEARCH

Asymmetric dimethylarginine inhibits HSP90 activity in pulmonary arterial endothelial cells: role of mitochondrial dysfunction

(2008) Neetu Sud et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine

(2008) Changkun Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells

(2008) P. J. Mishra et al.   CANCER RESEARCH

Overexpression and altered subcellular localization of autophagy-related 16-like 1 in human oral squamous-cell carcinoma: correlation with lymphovascular invasion and lymph-node metastasis

(2008) Hitomi Nomura et al.   HUMAN PATHOLOGY

Mitochondrial membrane cholesterol, the voltage dependent anion channel (VDAC), and the Warburg effect

(2008) Andrew M. Campbell et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Neuroprotection in Diet-Induced Ketotic Rat Brain after Focal Ischemia

(2008) Michelle A Puchowicz et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Asymmetric dimethylarginine in hematological malignancies: a preliminary study

(2008) Andrzej Szuba et al.   LEUKEMIA & LYMPHOMA

Stromal gene expression predicts clinical outcome in breast cancer

(2008) Greg Finak et al.   NATURE MEDICINE

Analysis of the adult human plasma metabolome

(2008) Kay A Lawton et al.   PHARMACOGENOMICS

Asymmetrical dimethylarginine in systemic sclerosis-related pulmonary arterial hypertension

(2008) T. Dimitroulas et al.   RHEUMATOLOGY

Breast cancer by proxy: can the microenvironment be both the cause and consequence?

(2008) Lone Rønnov-Jessen et al.   TRENDS IN MOLECULAR MEDICINE