Influence of multidrug resistance and drug transport proteins on chemotherapy drug metabolism

Mechanisms of Drug Resistance in Cancer Chemotherapy: Coordinated Role and Regulation of Efflux Transporters and Metabolizing Enzymes

(2013) Ramya Vadlapatla et al.   CURRENT PHARMACEUTICAL DESIGN

Taxanes: Old drugs, new oral formulations

(2013) Rajni A. Jibodh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of Glutathione in Cancer Progression and Chemoresistance

(2013) Nicola Traverso et al.   Oxidative Medicine and Cellular Longevity

Targeting cellular metabolism to improve cancer therapeutics

(2013) Y Zhao et al.   Cell Death & Disease

New Insight into P-Glycoprotein as a Drug Target

(2012) Albert Breier et al.   Anti-Cancer Agents in Medicinal Chemistry

Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters

(2012) Yakun Chen et al.   BIOCHEMICAL PHARMACOLOGY

Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance

(2012) Karthika Natarajan et al.   BIOCHEMICAL PHARMACOLOGY

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Contribution of tumoral and host solute carriers to clinical drug response

(2012) Jason A. Sprowl et al.   DRUG RESISTANCE UPDATES

Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance

(2012) Nitzan Gonen et al.   DRUG RESISTANCE UPDATES

Amplification and overexpression of the ABCC3 (MRP3) gene in primary breast cancer

(2012) Laura Partanen et al.   GENES CHROMOSOMES & CANCER

P-glycoprotein and cytochrome P450 3A act together in restricting the oral bioavailability of paclitaxel

(2012) Jeroen J.M.A. Hendrikx et al.   INTERNATIONAL JOURNAL OF CANCER

Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma

(2011) M Yamasaki et al.   BRITISH JOURNAL OF CANCER

Contribution of Abcc10 (Mrp7) to In Vivo Paclitaxel Resistance as Assessed in Abcc10-/- Mice

(2011) E. A. Hopper-Borge et al.   CANCER RESEARCH

The Coordinated Role of CYP450 Enzymes and P-gp in Determining Cancer Resistance to Chemotherapy

(2011) Amalia Azzariti et al.   CURRENT DRUG METABOLISM

Computational models for predicting substrates or inhibitors of P-glycoprotein

(2011) Lei Chen et al.   DRUG DISCOVERY TODAY

P-glycoprotein Substrate Models Using Support Vector Machines Based on a Comprehensive Data set

(2011) Zhi Wang et al.   Journal of Chemical Information and Modeling

The Emergence of Drug Transporter-Mediated Multidrug Resistance to Cancer Chemotherapy

(2011) Chung-Pu Wu et al.   MOLECULAR PHARMACEUTICS

A Critical Analysis of the Interplay between Cytochrome P450 3A and P-Glycoprotein: Recent Insights from Knockout and Transgenic Mice

(2011) R. A. B. van Waterschoot et al.   PHARMACOLOGICAL REVIEWS

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR

(2010) Antonia H. Tolson et al.   ADVANCED DRUG DELIVERY REVIEWS

Interaction of Tyrosine Kinase Inhibitors with the MDR-Related ABC Transporter Proteins

(2010) Xiao-Kun Wang et al.   CURRENT DRUG METABOLISM

Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathway

(2010) Xiao Qi Wang et al.   HEPATOLOGY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Therapeutic implications of renal anionic drug transporters

(2010) Rosalinde Masereeuw et al.   PHARMACOLOGY & THERAPEUTICS

Glutathione dysregulation and the etiology and progression of human diseases

(2009) Nazzareno Ballatori et al.   BIOLOGICAL CHEMISTRY

Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors

(2009) Philip Lazarus et al.   DRUG METABOLISM REVIEWS

P-glycoprotein expression in immortalised rat brain endothelial cells: comparisons following exogenously applied hydrogen peroxide and after hypoxia-reoxygenation

(2009) Samantha J. Robertson et al.   JOURNAL OF NEUROCHEMISTRY

The Role of Transporters in the Pharmacokinetics of Orally Administered Drugs

(2009) Sarah Shugarts et al.   PHARMACEUTICAL RESEARCH

How important is intestinal cytochrome P450 3A metabolism?

(2009) Antonius E. van Herwaarden et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Inhibition of multi-drug resistance of ovarian carcinoma by small interfering RNA targeting to MRP2 gene

(2008) Jia-jia Ma et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Combined action and regulation of phase II enzymes and multidrug resistance proteins in multidrug resistance in cancer

(2008) Irma Meijerman et al.   CANCER TREATMENT REVIEWS

Substrates and Inhibitors of Human Multidrug Resistance Associated Proteins and the Implications in Drug Development

(2008) Shu-Feng Zhou et al.   CURRENT MEDICINAL CHEMISTRY

The solute carrier (SLC) complement of the human genome: Phylogenetic classification reveals four major families

(2008) Robert Fredriksson et al.   FEBS LETTERS

Human Equilibrative Nucleoside Transporter 1 Levels Predict Response to Gemcitabine in Patients With Pancreatic Cancer

(2008) James J. Farrell et al.   GASTROENTEROLOGY

Profiling SLCO and SLC22 genes in the NCI-60 cancer cell lines to identify drug uptake transporters

(2008) M. Okabe et al.   MOLECULAR CANCER THERAPEUTICS

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

(2008) Paul D. Dobson et al.   NATURE REVIEWS DRUG DISCOVERY

Functional analysis of nonsynonymous single nucleotide polymorphism type ATP-binding cassette transmembrane transporter subfamily C member 3

(2008) Kazuhiro Kobayashi et al.   Pharmacogenetics and Genomics

ABC multidrug transporters: structure, function and role in chemoresistance

(2007) Frances J Sharom   PHARMACOGENOMICS