Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Generation and Characterization of an Immortalized Human Mesenchymal Stromal Cell Line

(2014) Magne Skårn et al.   STEM CELLS AND DEVELOPMENT

Selective inhibition of cell death in malignant vs normal B-cell precursors: implications for cAMP in development and treatment of BCP-ALL

(2013) E. H. Naderi et al.   BLOOD

Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment

(2013) V. L. Battula et al.   BLOOD

An expert opinion on pharmacologic approaches to reducing the cardiotoxicity of childhood acute lymphoblastic leukemia therapies

(2013) Patricia Zerra et al.   EXPERT OPINION ON PHARMACOTHERAPY

Neurocognitive and Neuroradiologic Central Nervous System Late Effects in Children Treated on Pediatric Oncology Group (POG) P9605 (Standard Risk) and P9201 (Lesser Risk) Acute Lymphoblastic Leukemia Protocols (ACCL0131)

(2013) Patricia K. Duffner et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Acute lymphoblastic leukaemia

(2013) Hiroto Inaba et al.   LANCET

Blocking ETV6/RUNX1-induced MDM2 overexpression by Nutlin-3 reactivates p53 signaling in childhood leukemia

(2013) U Kaindl et al.   LEUKEMIA

Pinch-1 was up-regulated in leukemia BMSC and its possible effect

(2012) Dongfeng Zeng et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group

(2012) Stephen P. Hunger et al.   JOURNAL OF CLINICAL ONCOLOGY

Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2

(2012) Sonia Alcolea et al.   JOURNAL OF LIPID RESEARCH

Cancer-Stimulated Mesenchymal Stem Cells Create a Carcinoma Stem Cell Niche via Prostaglandin E 2 Signaling

(2012) Hua-Jung Li et al.   Cancer Discovery

Notch-3 and Notch-4 signaling rescue from apoptosis human B-ALL cells in contact with human bone marrow-derived mesenchymal stromal cells

(2011) A. H. Nwabo Kamdje et al.   BLOOD

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Glucocorticoid receptor-mediated apoptosis: mechanisms of resistance in cancer cells

(2011) George Schlossmacher et al.   JOURNAL OF ENDOCRINOLOGY

Glucocorticoid resistance in paediatric acute lymphoblastic leukaemia

(2011) Vivek A Bhadri et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in ApcMin/+ mice

(2011) Kristoffer W Brudvik et al.   Molecular Cancer

Late Effects of Acute Lymphoblastic Leukemia Therapy in Patients Diagnosed at 0-20 Years of Age

(2011) L. L. Robison   Hematology-American Society of Hematology Education Program

Activation of cAMP signaling inhibits DNA damage-induced apoptosis in BCP-ALL cells through abrogation of p53 accumulation

(2009) E. H. Naderi et al.   BLOOD

The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment

(2009) A. Greenhough et al.   CARCINOGENESIS

Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation

(2009) Ching-Hon Pui et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bone marrow stroma cells regulate TIEG1 expression in acute lymphoblastic leukemia cells: Role of TGFβ/BMP-6 and TIEG1 in chemotherapy escape

(2008) Guri Døsen-Dahl et al.   INTERNATIONAL JOURNAL OF CANCER

Immunosuppressive properties of mesenchymal stem cells derived from bone marrow of patient with hematological malignant diseases

(2008) Zhao Zhi-Gang et al.   LEUKEMIA & LYMPHOMA