Curcumin represses mouse 3T3-L1 cell adipogenic differentiation via inhibiting miR-17-5p and stimulating the Wnt signalling pathway effector Tcf7l2

MicroRNA-17~92 inhibits colorectal cancer progression by targeting angiogenesis

(2016) Huabin Ma et al.   CANCER LETTERS

Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?

(2016) Q Chen et al.   CELL DEATH AND DIFFERENTIATION

Current Understanding on Role of the Wnt Signaling Pathway Effector TCF7L2 in Glucose Homeostasis

(2016) Tianru Jin   ENDOCRINE REVIEWS

MicroRNA-23a regulates 3T3-L1 adipocyte differentiation

(2016) Linyuan Shen et al.   GENE

Curcumin attenuates osteogenic differentiation and calcification of rat vascular smooth muscle cells

(2016) Menglin Hou et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Targeting adipose tissue in the treatment of obesity-associated diabetes

(2016) Christine M. Kusminski et al.   NATURE REVIEWS DRUG DISCOVERY

Acute Wnt pathway activation positively regulates leptin gene expression in mature adipocytes

(2015) Zong-Lan Chen et al.   CELLULAR SIGNALLING

Liver-Specific Expression of Dominant-Negative Transcription Factor 7-Like 2 Causes Progressive Impairment in Glucose Homeostasis

(2015) Wilfred Ip et al.   DIABETES

miR-184Regulates Pancreatic β-Cell Function According to Glucose Metabolism

(2015) Sudhir G. Tattikota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Short-Term Curcumin Gavage Sensitizes Insulin Signaling in Dexamethasone-Treated C57BL/6 Mice

(2015) Lili Tian et al.   JOURNAL OF NUTRITION

Inhibition of Dexamethasone-induced Fatty Liver Development by Reducing miR-17-5p Levels

(2015) William W Du et al.   MOLECULAR THERAPY

Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning

(2015) Cécile Jacovetti et al.   Nature Communications

The expression of dominant negative TCF7L2 in pancreatic beta cells during the embryonic stage causes impaired glucose homeostasis

(2015) Weijuan Shao et al.   Molecular Metabolism

MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression

(2015) Lekun Fang et al.   Oncotarget

Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes

(2014) E. Nilsson et al.   DIABETES

Roles of lncRNAs in pancreatic beta cell identity and diabetes susceptibility

(2014) Timothy J. Pullen et al.   Frontiers in Genetics

The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease

(2013) E Mogilyansky et al.   CELL DEATH AND DIFFERENTIATION

Banting Lecture 2012: Regulation of Adipogenesis: Toward New Therapeutics for Metabolic Disease

(2013) B. M. Spiegelman   DIABETES

MicroRNA-344 inhibits 3T3-L1 cell differentiation via targeting GSK3β of Wnt/β-catenin signaling pathway

(2013) Hu Chen et al.   FEBS LETTERS

Characterization of miR-210 in 3T3-L1 adipogenesis

(2013) Wei-Cheng Liang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

TCF3, a novel positive regulator of osteogenesis, plays a crucial role in miR-17 modulating the diverse effect of canonical Wnt signaling in different microenvironments

(2013) W Liu et al.   Cell Death & Disease

A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue

(2013) Tina Rönn et al.   PLoS Genetics

The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis

(2012) Wilfred Ip et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Adipose Tissue TCF7L2 Splicing Is Regulated by Weight Loss and Associates With Glucose and Fatty Acid Metabolism

(2012) D. Kaminska et al.   DIABETES

Curcumin Extract for Prevention of Type 2 Diabetes

(2012) S. Chuengsamarn et al.   DIABETES CARE

P21-Activated Protein Kinase 1 (Pak1) Mediates the Cross Talk between Insulin and β-Catenin on Proglucagon Gene Expression and Its Ablation Affects Glucose Homeostasis in Male C57BL/6 Mice

(2012) Yuting Alex Chiang et al.   ENDOCRINOLOGY

Curcumin Prevents High Fat Diet Induced Insulin Resistance and Obesity via Attenuating Lipogenesis in Liver and Inflammatory Pathway in Adipocytes

(2012) Weijuan Shao et al.   PLoS One

miR-17-5p and miR-106a are involved in the balance between osteogenic and adipogenic differentiation of adipose-derived mesenchymal stem cells

(2012) Hongling Li et al.   Stem Cell Research

A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells

(2011) G Zhu et al.   ONCOGENE

Curcumin-induced suppression of adipogenic differentiation is accompanied by activation of Wnt/β-catenin signaling

(2010) Jiyun Ahn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Oltipraz upregulates the nuclear respiratory factor 2 alpha subunit (NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice

(2010) Z. Yu et al.   DIABETOLOGIA

Genotype and Tissue-Specific Effects on Alternative Splicing of the Transcription Factor 7-Like 2 Gene in Humans

(2010) Ashis K. Mondal et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets

(2010) Andreas Weise et al.   NUCLEIC ACIDS RESEARCH

Tissue-specific alternative splicing of TCF7L2

(2009) Ludmila Prokunina-Olsson et al.   HUMAN MOLECULAR GENETICS

MicroRNA MiR-17 retards tissue growth and represses fibronectin expression

(2009) Sze Wan Shan et al.   NATURE CELL BIOLOGY

P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine

(2009) J Sun et al.   ONCOGENE

Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters

(2008) Andrea Ventura et al.   CELL

Dietary Curcumin Significantly Improves Obesity-Associated Inflammation and Diabetes in Mouse Models of Diabesity

(2008) Stuart P. Weisberg et al.   ENDOCRINOLOGY

Glucagon-like Peptide-1 Activation of TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell Proliferation

(2008) Zhengyu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130

(2008) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adipogenesis and WNT signalling

(2008) Constantinos Christodoulides et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM