The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis

Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism

(2011) L. Norton et al.   DIABETOLOGIA

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes

(2011) J. M. Locke et al.   DIABETOLOGIA

Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism

(2011) D. Savic et al.   GENOME RESEARCH

Wnt Signaling Regulates Hepatic Metabolism

(2011) H. Liu et al.   Science Signaling

Insulin alters the expression of components of the Wnt signaling pathway including TCF-4 in the intestinal cells

(2010) Jane Sun et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Can the Genetics of Type 1 and Type 2 Diabetes Shed Light on the Genetics of Latent Autoimmune Diabetes in Adults?

(2010) Struan F. A. Grant et al.   ENDOCRINE REVIEWS

C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: Role of mitogen-activated protein kinases

(2010) Liang Xi et al.   HEPATOLOGY

Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas

(2010) Joshua Columbus et al.   JOURNAL OF ENDOCRINOLOGY

TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet  -Cells

(2009) G. da Silva Xavier et al.   DIABETES

Regulation of wingless-type MMTV integration site family (WNT) signalling in pancreatic islets from wild-type and obese mice

(2009) J. Krützfeldt et al.   DIABETOLOGIA

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

(2009) K. Pilgaard et al.   DIABETOLOGIA

Wnt-signalling and the Metabolic Syndrome

(2009) S. Schinner   HORMONE AND METABOLIC RESEARCH

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

(2009) Luan Shu et al.   HUMAN MOLECULAR GENETICS

P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine

(2009) J Sun et al.   ONCOGENE

Expression of the transcription factor 7-like 2 gene (TCF7L2) in human adipocytes is down regulated by insulin

(2008) Maja Ahlzén et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis

(2008) P H Sugden et al.   BRITISH JOURNAL OF PHARMACOLOGY

Wnt and beyond Wnt: Multiple mechanisms control the transcriptional property of β-catenin

(2008) Tianru Jin et al.   CELLULAR SIGNALLING

Cross Talk between the Insulin and Wnt Signaling Pathways: Evidence from Intestinal Endocrine L Cells

(2008) Fenghua Yi et al.   ENDOCRINOLOGY

Impact ofTCF7L2rs7903146 on Insulin Secretion and Action in Young and Elderly Danish Twins

(2008) Lise Wegner et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Minireview: The Wnt Signaling Pathway Effector TCF7L2 and Type 2 Diabetes Mellitus

(2008) Tianru Jin et al.   MOLECULAR ENDOCRINOLOGY

Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling

(2008) D. C. Hay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA