Cold-inducible RNA-binding protein through TLR4 signaling induces mitochondrial DNA fragmentation and regulates macrophage cell death after trauma

Tissue damage negatively regulates LPS-induced macrophage necroptosis

(2016) Z Li et al.   CELL DEATH AND DIFFERENTIATION

Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9

(2016) Irma Garcia-Martinez et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

(2016) Q. Zhou et al.   SCIENCE

Plasma Mitochondrial DNA—a Novel DAMP in Pediatric Sepsis

(2016) Valentina Di Caro et al.   SHOCK

Cold-inducible RNA-binding protein causes endothelial dysfunction via activation of Nlrp3 inflammasome

(2016) Weng-Lang Yang et al.   Scientific Reports

Programmed Necrosis in the Cross Talk of Cell Death and Inflammation

(2015) Francis Ka-Ming Chan et al.   Annual Review of Immunology

Circulating mitochondrial DNA and Toll-like receptor 9 are associated with vascular dysfunction in spontaneously hypertensive rats

(2015) Cameron G. McCarthy et al.   CARDIOVASCULAR RESEARCH

Liver-Resident Macrophage Necroptosis Orchestrates Type 1 Microbicidal Inflammation and Type-2-Mediated Tissue Repair during Bacterial Infection

(2015) Camille Blériot et al.   IMMUNITY

The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013

(2015) Juanita A Haagsma et al.   INJURY PREVENTION

Necroptosis and its role in inflammation

(2015) Manolis Pasparakis et al.   NATURE

The diverse role of RIP kinases in necroptosis and inflammation

(2015) John Silke et al.   NATURE IMMUNOLOGY

RIPK1 Regulates RIPK3-MLKL-Driven Systemic Inflammation and Emergency Hematopoiesis

(2014) James A. Rickard et al.   CELL

NADPH oxidases: an overview from structure to innate immunity-associated pathologies

(2014) Arvind Panday et al.   Cellular & Molecular Immunology

The Necroptosis Adaptor RIPK3 Promotes Injury-Induced Cytokine Expression and Tissue Repair

(2014) Kenta Moriwaki et al.   IMMUNITY

Mitochondria-targeted Ogg1 and Aconitase-2 Prevent Oxidant-induced Mitochondrial DNA Damage in Alveolar Epithelial Cells

(2014) Seok-Jo Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The systemic immune response to trauma: an overview of pathophysiology and treatment

(2014) Janet M Lord et al.   LANCET

Post-transcriptional coordination of immunological responses by RNA-binding proteins

(2014) Panagiota Kafasla et al.   NATURE IMMUNOLOGY

Loss of Cytochrome c Oxidase Promotes RAS-Dependent ROS Production from the ER Resident NADPH Oxidase, Yno1p, in Yeast

(2013) Jane E. Leadsham et al.   Cell Metabolism

Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis

(2013) Xiaoling Qiang et al.   NATURE MEDICINE

CHIP has a protective role against oxidative stress-induced cell death through specific regulation of Endonuclease G

(2013) J S Lee et al.   Cell Death & Disease

The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis

(2012) Jixi Li et al.   CELL

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

Mitochondria and Mitophagy

(2012) Dieter A. Kubli et al.   CIRCULATION RESEARCH

Cold-Inducible RNA-Binding Protein Modulates Circadian Gene Expression Posttranscriptionally

(2012) J. Morf et al.   SCIENCE

How tissue injury alarms the immune system and causes a systemic inflammatory response syndrome

(2012) Jérôme Pugin   Annals of Intensive Care

Trauma alarmins as activators of damage-induced inflammation

(2011) J. Manson et al.   BRITISH JOURNAL OF SURGERY

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Mitochondrial fission controls DNA fragmentation by regulating endonuclease G

(2010) Jincheng Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of hemorrhage in the induction of systemic inflammation and remote organ damage: Analysis of combined pseudo-fracture and hemorrhagic shock

(2010) Roman Pfeifer et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Oxidative stress triggers neuronal caspase-independent death: Endonuclease G involvement in programmed cell death-type III

(2009) Gavin C. Higgins et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Oxidative stress induces degradation of mitochondrial DNA

(2009) Inna Shokolenko et al.   NUCLEIC ACIDS RESEARCH

Male Gender is Associated With Excessive IL-6 Expression Following Severe Injury

(2009) Jason L. Sperry et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

No death without life: vital functions of apoptotic effectors

(2008) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Characterization of the gender dimorphism after injury and hemorrhagic shock: Are hormonal differences responsible?*

(2008) Jason L. Sperry et al.   CRITICAL CARE MEDICINE

Generation of ρ 0 cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses

(2008) Alexandra Kukat et al.   NUCLEIC ACIDS RESEARCH