Trauma alarmins as activators of damage-induced inflammation

HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

(2011) Ulf Andersson et al.   Annual Review of Immunology

Surviving the first hours in sepsis: getting the basics right (an intensivist's perspective)

(2011) R. Daniels   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Heat shock proteins and high mobility group box 1 protein lack cytokine function

(2011) Min-Fu Tsan   JOURNAL OF LEUKOCYTE BIOLOGY

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

(2011) Dmitri V. Krysko et al.   TRENDS IN IMMUNOLOGY

The alarmin functions of high-mobility group proteins

(2010) De Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin

(2010) P. Tewary et al.   BLOOD

Complications of Massive Transfusion

(2010) Kristen C. Sihler et al.   CHEST

Uric acid promotes an acute inflammatory response to sterile cell death in mice

(2010) Hajime Kono et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunonutrition in High-Risk Surgical Patients

(2010) Paul E. Marik et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Diagnosis-Dependent Relationships between Cytokine Levels and Survival in Patients Admitted for Surgical Critical Care

(2010) Tjasa Hranjec et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

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(2010) Meng Xiang et al.   MOLECULAR MEDICINE

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

GFAP and S100B are biomarkers of traumatic brain injury: An observational cohort study

(2010) P. E. Vos et al.   NEUROLOGY

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

(2010) B. McDonald et al.   SCIENCE

MITOCHONDRIAL DNA IS RELEASED BY SHOCK AND ACTIVATES NEUTROPHILS VIA P38 MAP KINASE

(2010) Qin Zhang et al.   SHOCK

Early Release of Soluble Receptor for Advanced Glycation Endproducts After Severe Trauma in Humans

(2010) Mitchell J. Cohen et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008

(2009) R Phillip Dellinger et al.   CRITICAL CARE MEDICINE

Monocyte activation by necrotic cells is promoted by mitochondrial proteins and formyl peptide receptors

(2009) Elliott D. Crouser et al.   CRITICAL CARE MEDICINE

Role of systemic inflammatory response in predicting survival in patients with primary operable cancer

(2009) Campbell SD Roxburgh et al.   Future Oncology

Current theories on the pathophysiology of multiple organ failure after trauma

(2009) Takeshi Tsukamoto et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Nucleophosmin may act as an alarmin: implications for severe sepsis

(2009) Yuko Nawa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HMGB1 loves company

(2009) Marco E. Bianchi   JOURNAL OF LEUKOCYTE BIOLOGY

Early Cytokine Production Risk Stratifies Trauma Patients for Multiple Organ Failure

(2009) Kenneth M. Jastrow et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Extracellular histones are major mediators of death in sepsis

(2009) Jun Xu et al.   NATURE MEDICINE

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Calcium-regulated intramembrane proteolysis of the RAGE receptor

(2008) Arnaud Galichet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Binding of S100 proteins to RAGE: An update

(2008) Estelle Leclerc et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

(2008) Martin Andrassy et al.   CIRCULATION

The danger within: endogenous danger signals, atopy and asthma

(2008) M. A. M. Willart et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY