Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress
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Title
Klotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress
Authors
Keywords
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Journal
Cell Death & Disease
Volume 8, Issue 8, Pages e2972
Publisher
Springer Nature
Online
2017-08-03
DOI
10.1038/cddis.2017.365
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Note: Only part of the references are listed.- Klotho Deficiency Aggravates Tacrolimus-Induced Renal Injury via the Phosphatidylinositol 3-Kinase-Akt-Forkhead Box Protein O Pathway
- (2016) Jian Jin et al. AMERICAN JOURNAL OF NEPHROLOGY
- Inhibition of dipeptidyl peptidase IV protects tacrolimus-induced kidney injury
- (2015) Sun W Lim et al. LABORATORY INVESTIGATION
- The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System
- (2014) Ella Zeldich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The renin-angiotensin system and aging in the kidney
- (2014) Hye Eun Yoon et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- Modulation of mitochondrial bioenergetics in a skeletal muscle cell line model of mitochondrial toxicity
- (2014) William Dott et al. Redox Biology
- Influence of N-Acetylcysteine on Klotho Expression and Its Signaling Pathway in Experimental Model of Chronic Cyclosporine Nephropathy in Mice
- (2013) Shang Guo Piao et al. TRANSPLANTATION
- Small-molecule Klotho enhancers as novel treatment of neurodegeneration
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- Statin Upregulates the Expression of Klotho, an Anti-Aging Gene, in Experimental Cyclosporine Nephropathy
- (2012) Hye Eun Yoon et al. NEPHRON EXPERIMENTAL NEPHROLOGY
- Identification of novel small molecules that elevate Klotho expression
- (2011) Gwendalyn D. King et al. BIOCHEMICAL JOURNAL
- FoxO transcription factors; Regulation by AKT and 14-3-3 proteins
- (2011) Guri Tzivion et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
- (2011) Xin Zhang et al. NATURE CELL BIOLOGY
- Amelioration of aminoglycoside nephrotoxicity requires protection of renal mitochondria
- (2010) Dmitry B. Zorov KIDNEY INTERNATIONAL
- Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy
- (2010) H. E. Yoon et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Established and Newly Proposed Mechanisms of Chronic Cyclosporine Nephropathy
- (2009) Hye Eun Yoon et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a)
- (2008) B. M. Emerling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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